The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
An update on bioactive plant lignans
Abstract
Lignans are a class of secondary plant metabolites produced by oxidative dimerization of two phenylpropanoid units. Although their molecular backbone consists only of two phenylpropane (C6-C3) units, lignans show an enormous structural diversity. There is a growing interest in lignans and their synthetic derivatives due to applications in cancer chemotherapy and various other pharmacological effects. This review deals with lignans possessing anticancer, antioxidant, antimicrobial, anti-inflammatory and immunosuppressive activities, and comprises the data reported in more than 100 peer-reviewed articles, so as to highlight the recently reported bioactive lignans that could be a first step towards the development of potential new therapeutic agents.
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Vanharanta, M., Voutilainen, S., Lakka, T. A., van der Lee, M., Adlercreutz, H., & Salonen, J. T. (1999) · The Lancet · doi:10.1016/s0140-6736(99)05031-x · Cited by 246
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Yadav, V., Krishnan, A., & Vohora, D. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2019.112255 · Cited by 196
Small molecules as inhibitors of PCSK9: Current status and future challenges
Xu, S., Luo, S., Zhu, Z., & Xu, J. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.11.011 · Cited by 85
Pinto, O., Sardinha, J., Vaz, P. D., Piedade, F., Calhorda, M. J., Abramovitch, R., Nazareth, N., Pinto, M., Nascimento, M. S. J., & Rauter, A. P. (2011) · Journal of Medicinal Chemistry · doi:10.1021/jm101182s · Cited by 27
Metadata
- Authors
- Saleem, M., Kim, H. J., Ali, M. S., & Lee, Y. S.
- Venue
- Natural Product Reports
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2005
- Volume
- 22
- Issue
- 6
- Pages
- 696
- ISSN
- 0265-0568 (ISSN-L)
- 1460-4752
- OpenAlex
- W2151972443
- Cited by
- 510
- References
- 1
- FWCI
- 3.23
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
