The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly
Open accessAbstract
A flow process for the multi-step synthesis of the alkaloid natural product (+/-)-oxomaritidine is described, mediated through the use of microfluidic pumping systems that progress material through various packed columns containing immobilized reagents, catalysts, scavengers or catch and release agents; our route involves the combination of seven separate synthetic steps linked into one continuous sequence utilizing flow chemistry.
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Cites
Ley, S. V., Baxendale, I. R., Bream, R. N., Jackson, P. S., Leach, A. G., Longbottom, D. A., Nesi, M., Scott, J. S., Storer, R. I., & Taylor, S. J. (2000) · Journal of the Chemical Society, Perkin Transactions 1 · doi:10.1039/b006588i · Cited by 693
Self-citationMicro reactors: principles and applications in organic synthesis
Fletcher, P. D. I., Haswell, S. J., Pombo-Villar, E., Warrington, B. H., Watts, P., Wong, S. Y. F., & Zhang, X. (2002) · Tetrahedron · doi:10.1016/s0040-4020(02)00432-5 · Cited by 468
Continuous Flow Techniques in Organic Synthesis
Jas, G., & Kirschning, A. (2003) · Chemistry – A European Journal · doi:10.1002/chem.200305212 · Cited by 466
New tools and concepts for modern organic synthesis
Ley, S. V., & Baxendale, I. R. (2002) · Nature Reviews Drug Discovery · doi:10.1038/nrd871 · Cited by 239
Self-citationMicroreactor-based reaction optimization in organic chemistry—glycosylation as a challenge
Ratner, D. M., Murphy, E. R., Jhunjhunwala, M., Snyder, D. A., Jensen, K. F., & Seeberger, P. H. (2004) · Chemical Communications · doi:10.1039/b414503h · Cited by 181
Saaby, S., Knudsen, K. R., Ladlow, M., & Ley, S. V. (2005) · Chemical Communications · doi:10.1039/b504854k · Cited by 123
Self-citationLey, S. V., Schucht, O., Thomas, A. W., et al. (1999) · Journal of the Chemical Society Perkin Transactions 1 · doi:10.1039/a901798d · Cited by 102
Self-citationMuscarine, imidazole, oxazole, thiazole, Amaryllidaceae and Sceletium alkaloids
Jin, Z., Li, Z., & Huang, R. (2002) · Natural Product Reports · doi:10.1039/b108923b · Cited by 85
Michael reactions carried out using a bench-top flow system
Bonfils, F., Cazaux, I., Hodge, P., & Caze, C. (2005) · Organic & Biomolecular Chemistry · doi:10.1039/b515241k · Cited by 69
Automated Flow-Through Synthesis of Heterocyclic Thioethers
Jönsson, D., Warrington, B. H., & Ladlow, M. (2004) · Journal of Combinatorial Chemistry · doi:10.1021/cc0499486 · Cited by 29
Cited by
Taming hazardous chemistry by continuous flow technology
Movsisyan, M., Delbeke, E. I. P., Berton, J. K. E. T., Battilocchio, C., Ley, S. V., & Stevens, C. V. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00902b · Cited by 692
Self-citationMicrochemical systems for continuous-flow synthesis
Hartman, R. L., & Jensen, K. F. (2009) · Lab on a Chip · doi:10.1039/b906343a · Cited by 508
A field guide to flow chemistry for synthetic organic chemists
Capaldo, L., Wen, Z., & Noël, T. (2023) · Chemical Science · doi:10.1039/d3sc00992k · Cited by 402
Continuous Flow Reactors, a Tool for the Modern Synthetic Chemist
Wiles, C., & Watts, P. (2008) · European Journal of Organic Chemistry · doi:10.1002/ejoc.200701041 · Cited by 310
Microreactor Synthesis of β‐Peptides
Flögel, O., Codée, J. D. C., Seebach, D., & Seeberger, P. H. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200602167 · Cited by 108
Metadata
- Authors
- Baxendale, I. R., Deeley, J., Griffiths-Jones, C. M., Ley, S. V., Saaby, S., & Tranmer, G. K.
- Venue
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2006
- Issue
- 24
- Pages
- 2566
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W2149135858
- Cited by
- 331
- References
- 10
- FWCI
- 22.91
- Type
- journal article
- Language
- en
- Open access
- green
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- Baxendale, I. R., Deeley, J., Griffiths-Jones, C. M., Ley, S. V., Saaby, S., & Tranmer, G. K. (2006). A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly. Chemical Communications. https://doi.org/10.1039/b600382f
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
