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Cited by 195

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Antibody conjugated magnetic PLGA nanoparticles for diagnosis and treatment of breast cancer

Open access
Yang, Jaemoon, Lee, Choong-Hwan, Park, Joseph, Seo, Sungbaek, Lim, Eun-Kyung, Song, Yong Jin, Suh, Jin-Suck, Yoon, Ho-Geun, Huh, Yong-Min, Haam, Seungjoo·2007·Journal of Materials Chemistry
DOI 10.1039/b702538f
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Abstract

DOX–magnetic PLGA nanoparticles conjugated with well-tailored antibodies were synthesized for the detection and therapy of breast cancer. Magnetic nanocrystals embedded in polymeric nanoparticles did not inhibit the nanoparticle formulation or drug release kinetics. The multimodal nanoparticles demonstrated remarkable cancer cell affinity and ultrasensitivity via magnetic resonance imaging. Furthermore, the loaded anticancer drugs were released and sustained for three weeks.

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Metadata

Authors
Yang, J., Lee, C.-H., Park, J., Seo, S., Lim, E.-K., Song, Y. J., Suh, J.-S., Yoon, H.-G., Huh, Y.-M., & Haam, S.
Venue
Journal of Materials Chemistry
Publisher
Royal Society of Chemistry (RSC)
Published
2007
Volume
17
Issue
26
Pages
2695
ISSN
  • 0959-9428 (ISSN-L)
  • 1364-5501
DOI
10.1039/b702538f
OpenAlex
W2015921952
Cited by
195
References
0
FWCI
5.46
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Antibody conjugated magnetic PLGA nanoparticles for diagnosis and treatment of breast cancer. https://app.cochat.ai/papers/10.1039/b702538f
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Yang, J., Lee, C.-H., Park, J., Seo, S., Lim, E.-K., Song, Y. J., Suh, J.-S., Yoon, H.-G., Huh, Y.-M., & Haam, S. (2007). Antibody conjugated magnetic PLGA nanoparticles for diagnosis and treatment of breast cancer. Journal of Materials Chemistry. https://doi.org/10.1039/b702538f

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