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Combining supramolecular chemistry with biology

Uhlenheuer, Dana A., Petkau, Katja, Brunsveld, Luc·2010·Chemical Society Reviews

Abstract

Supramolecular chemistry has primarily found its inspiration in biological molecules, such as proteins and lipids, and their interactions. Currently the supramolecular assembly of designed compounds can be controlled to great extent. This provides the opportunity to combine these synthetic supramolecular elements with biomolecules for the study of biological phenomena. This tutorial review focuses on the possibilities of the marriage of synthetic supramolecular architectures and biological systems. It highlights that synthetic supramolecular elements are for example ideal platforms for the recognition and modulation of proteins and cells. The unique features of synthetic supramolecular systems with control over size, shape, valency, and interaction strength allow the generation of structures fitting the demands to approach the biological problems at hand. Supramolecular chemistry has come full circle, studying the biology and its molecules which initially inspired its conception.

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Cites

Show all 38 references

Research works printed but not linked: 10

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Metadata

Authors
Uhlenheuer, D. A., Petkau, K., & Brunsveld, L.
Venue
Chemical Society Reviews
Published
2010
Volume
39
Issue
8
Pages
2817
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
OpenAlex
W2019857653
Cited by
377
References
38
FWCI
1.05
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Combining supramolecular chemistry with biology. https://app.cochat.ai/papers/10.1039/b820283b
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Uhlenheuer, D. A., Petkau, K., & Brunsveld, L. (2010). Combining supramolecular chemistry with biology. Chemical Society Reviews. https://doi.org/10.1039/b820283b

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