CoChat
Sign Up
Cited by 278Photochromic and Fluorescence ChemistryNitric Oxide and Endothelin EffectsPhotopolymerization techniques and applications

The DOI matches its Crossref record; 62 of the 64 references it cites were found in a registry or an index.

Light-controlled nitric oxide delivering molecular assemblies

Sortino, Salvatore·2010·Chemical Society Reviews
DOI 10.1039/b908663n
Open this paper in CoChat — free account

Abstract

The multiple roles nitric oxide (NO) plays as a bioregulatory, anticancer, antimicrobial and antioxidant agent has triggered an explosive interest in recent years in compounds able to deliver this diatomic radical for therapeutic purposes. A major issue associated with NO donors is the precise control of the NO release, which effect is highly concentration and flux dependent. Light represents a convenient non-invasive on/off trigger to deliver NO on demand since it allows the accurate control of site, timing and dosage. The assembling of NO photodonors through different approaches may lead to intriguing light-responsive molecular constructs including nanostructured films, polymers, gels, nanoparticles and molecular conjugates which exhibit promising potential in view of practical applications. This tutorial review illustrates the recent research from our and other laboratories towards the fabrication of these molecular assemblies, highlighting the logical design and the relevance in the biomedical field. Therefore, this review is aimed to be a source of inspiration for a wide range of scientists belonging to the chemical, materials science and biochemical communities, facing the common challenge of fabricating controllable NO dispensers.

Overview

Integrity signals

Registry

Crossref · 10.1039/b908663n

Cites

62 of 62 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Citations

Cites

Show all 64 references

Research works printed but not linked: 2

  1. Murad, 1999, Angew. Chem., Int. Ed., 38, 1856, 10.1002/(SICI)1521-3773(19990712)38:13/14<1856::AID-ANIE1856>3.0.CO;2-D · DOI
  2. Furchgott, 1999, Angew. Chem., Int. Ed., 38, 1870, 10.1002/(SICI)1521-3773(19990712)38:13/14<1870::AID-ANIE1870>3.0.CO;2-8 · DOI

Cited by

Sorted by citations

See all 278

Related

Metadata

Authors
Sortino, S.
Affiliations
University of Catania (IT)
Corresponding author
Sortino, Salvatore
ORCID
Sortino, Salvatore
Venue
Chemical Society Reviews
Publisher
Royal Society of Chemistry (RSC)
Published
2010
Volume
39
Issue
8
Pages
2903
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
DOI
10.1039/b908663n
OpenAlex
W2086971976
Cited by
277
References
64
Citations by year
2026: 14 · 2025: 14 · 2024: 21 · 2023: 15 · 2022: 16 · 2021: 15 · 2020: 22 · 2019: 19 · 2018: 18 · 2017: 22 · 2016: 17 · 2015: 18 · 2014: 11 · 2013: 22 · 2012: 13
FWCI
0.85
Type
journal article
Language
en
Open access
closed
Locations
  • Chemical Society Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Materials Science › Materials Chemistry › Photochromic and Fluorescence Chemistry
  • Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
  • Physical Sciences › Chemistry › Organic Chemistry › Photopolymerization techniques and applications
Keywords
nitric oxide donors, molecular assembly, nanostructured films, polymers, gels, nanoparticles, on-demand drug delivery, biomedical applications
MeSH terms
Light, Nitric Oxide, Polymers, Drug Delivery Systems, Nanoparticles

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review