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Designer self-assembling peptide nanofiber biological materials

Hauser, Charlotte A. E., Zhang, Shuguang·2010·Chemical Society Reviews

Abstract

Scientists and bioengineers have dreamed of designing materials from the bottom up with the finest detail and ultimate control at the single molecular level. The discovery of a class of self-assembling peptides that spontaneously undergo self-organization into well-ordered structures opened a new avenue for molecular fabrication of biological materials. Since this discovery, diverse classes of short peptides have been invented with broad applications, including 3D tissue cell culture, reparative and regenerative medicine, tissue engineering, slow drug release and medical device development. Molecular design of new materials using short peptides is poised to become increasingly important in biomedical research, biomedical technology and medicine, and is covered in this tutorial review.

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Metadata

Authors
Hauser, C. A. E., & Zhang, S.
Venue
Chemical Society Reviews
Published
2010
Volume
39
Issue
8
Pages
2780
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
OpenAlex
W2099995006
Cited by
370
References
0
FWCI
1.01
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Designer self-assembling peptide nanofiber biological materials. https://app.cochat.ai/papers/10.1039/b921448h
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Hauser, C. A. E., & Zhang, S. (2010). Designer self-assembling peptide nanofiber biological materials. Chemical Society Reviews. https://doi.org/10.1039/b921448h

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