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New developments in ordered mesoporous materials for drug delivery
Abstract
Silica-based ordered mesoporous materials have experienced impressive consideration in drug delivery applications since they were first employed as drug delivery systems back in 2001. The possibility of tuning the physicochemical properties of the matrices together with the development of stimuli-responsive technologies are two of the main reasons for the great scientific attention on these bioceramics as conventional drug delivery systems. However, the properties of ordered mesoporous silicas have fuelled the possibility of covalently grafting certain biomolecules to stimulate selected target cells able to create new tissue, powering their employment in tissue engineering technologies, especially for bone tissue regeneration.
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“Furthermore, pore size, surface functionalization, and surface area are the main factors influencing drug loading and release behavior.55”
From Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles (2019) · cites this paper as [55]
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Drug release from ordered mesoporous silicas
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Self-citation
Metadata
- Authors
- Manzano, M., & Vallet-Regí, M.
- Affiliations
- Universidad Complutense de Madrid (ES)
- ORCID
- Manzano, Miguel
- Venue
- Journal of Materials Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 20
- Issue
- 27
- Pages
- 5593
- ISSN
- 0959-9428 (ISSN-L)
- 1364-5501
- OpenAlex
- W2035924623
- Cited by
- 359
- References
- 106
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 8 · 2023: 16 · 2022: 16 · 2021: 26 · 2020: 18 · 2019: 26 · 2018: 30 · 2017: 24 · 2016: 33 · 2015: 32 · 2014: 21 · 2013: 30 · 2012: 30
- FWCI
- 15.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Materials Chemistry (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Mesoporous Materials and Catalysis
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Physical Sciences › Earth and Planetary Sciences › Geochemistry and Petrology › Clay minerals and soil interactions
- Keywords
- ordered mesoporous silica, drug delivery systems, stimuli-responsive materials, bioceramics, tissue engineering, bone regeneration
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