Biocompatibility and drug delivery systems

Fabrication of novel biomaterials through molecular self-assembly

Zhang, S. (2003) · Nature Biotechnology · doi:10.1038/nbt874 · Cited by 3,353 · see citing works

On the mechanisms of biocompatibility

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Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers

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New Challenges in Biomaterials

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Nanostructured materials for applications in drug delivery and tissue engineering

Goldberg, M. S., Langer, R., & Jia, X. (2007) · Journal of Biomaterials Science Polymer Edition · doi:10.1163/156856207779996931 · Cited by 1,057 · see citing works

On the nature of biomaterials

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Studies on succinate-tetrazolium reductase systems

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Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells

Anderson, D. G., Levenberg, S., & Langer, R. (2004) · Nature Biotechnology · doi:10.1038/nbt981 · Cited by 747 · see citing works

The biocompatibility of mesoporous silicates

Hudson, S. P., Padera, R. F., Langer, R., & Kohane, D. S. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.07.007 · Cited by 538 · see citing works

Cell‐Responsive Synthetic Hydrogels

Lütolf, M. P., Raeber, G. P., Zisch, A. H., Tirelli, N., & Hubbell, J. A. (2003) · Advanced Materials · doi:10.1002/adma.200304621 · Cited by 526 · see citing works

Microparticles and nanoparticles for drug delivery

Kohane, D. S. (2006) · Biotechnology and Bioengineering · doi:10.1002/bit.21301 · Cited by 517 · see citing works

Clinical biocompatibility of biodegradable orthopaedic implants for internal fixation: a review

Böstman, O. M., & PIHLAJAMÄKI, H. K. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00129-0 · Cited by 509 · see citing works

Synthesis and RGD peptide modification of a new biodegradable copolymer: poly(lactic acid-co-lysine)

Barrera, D. A., Zylstra, E., Lansbury, P. T., & Langer, R. (1993) · Journal of the American Chemical Society · doi:10.1021/ja00076a077 · Cited by 456 · see citing works

A Drug-Eluting Contact Lens

Ciolino, J. B., Hoare, T. R., Iwata, N. G., Behlau, I., Dohlman, C. H., Langer, R., & Kohane, D. S. (2009) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.08-2826 · Cited by 248 · see citing works

In situ cross-linkable hyaluronic acid hydrogels prevent post-operative abdominal adhesions in a rabbit model

Yeo, Y., Highley, C. B., Bellas, E., et al. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.04.043 · Cited by 229 · see citing works

Biodegradable polymeric microspheres and nanospheres for drug delivery in the peritoneum

Kohane, D. S., Tse, J. Y., Yeo, Y., et al. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30654 · Cited by 218 · see citing works

Prolongation of sciatic nerve blockade by in situ cross-linked hyaluronic acid

Jia, X., Colombo, G., Padera, R. F., Langer, R., & Kohane, D. S. (2004) · Biomaterials · doi:10.1016/j.biomaterials.2003.12.012 · Cited by 191 · see citing works

Glucocorticoids Prolong Rat Sciatic Nerve Blockade In Vivo from Bupivacaine Microspheres

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Current trends in biocompatibility testing

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A Re-examination of Tetrodotoxin for Prolonged Duration Local Anesthesia

Kohane, D. S., Yieh, J., Lu, N. T., et al. (1998) · Anesthesiology · doi:10.1097/00000542-199807000-00019 · Cited by 144 · see citing works

Prolonged duration local anesthesia with minimal toxicity

Epstein-Barash, H., Shichor, I., Kwon, A. H., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0900598106 · Cited by 143 · see citing works

Injectable in situ cross-linking hydrogels for local antifungal therapy

Hudson, S. P., Langer, R., Fink, G. R., & Kohane, D. S. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.11.016 · Cited by 138 · see citing works

Anti-inflammatory function of an in situ cross-linkable conjugate hydrogel of hyaluronic acid and dexamethasone

Ito, T., Fraser, I. P., Yeo, Y., Highley, C. B., Bellas, E., & Kohane, D. S. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2006.12.012 · Cited by 129 · see citing works

Prolonged duration local anesthesia from tetrodotoxin-enhanced local anesthetic microspheres

Kohane, D. S., Smith, S. E., Louis, D. N., et al. (2003) · Pain · doi:10.1016/s0304-3959(03)00049-6 · Cited by 123 · see citing works

Polymers in the prevention of peritoneal adhesions

Yeo, Y., & Kohane, D. S. (2007) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2007.03.027 · Cited by 118 · see citing works

Antifungal hydrogels

Zumbuehl, A., Ferreira, L., Kuhn, D. M., Astashkina, A. I., Long, L. A., Yeo, Y., Iaconis, T., Ghannoum, M. A., Fink, G. R., Langer, R., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705250104 · Cited by 117 · see citing works

In vivo biocompatibility of implantable delivery systems and biomaterials

Anderson, J. M. (1994) · European Journal of Pharmaceutics and Biopharmaceutics · Cited by 116 · see citing works

Bone tissue response to biodegradable polymers used for intra medullary fracture fixation: A long-term in vivo study in sheep femora

van der Elst, M., Klein, C. P. A. T., Hogervorst, J. M. A., Patka, P., & Haarman, H. J. T. M. (1999) · Biomaterials · doi:10.1016/s0142-9612(98)00117-3 · Cited by 109 · see citing works

Local Myotoxicity from Sustained Release of Bupivacaine from Microparticles

Padera, R. F., Bellas, E., Tse, J. Y., et al. (2008) · Anesthesiology · doi:10.1097/aln.0b013e31816c8a48 · Cited by 107 · see citing works

In Situ Cross-linkable Hyaluronan Hydrogels Containing Polymeric Nanoparticles for Preventing Postsurgical Adhesions

Yeo, Y., Ito, T., Bellas, E., et al. (2007) · Annals of Surgery · doi:10.1097/01.sla.0000251519.49405.55 · Cited by 106 · see citing works

Biocompatibility of lipid‐protein‐sugar particles containing bupivacaine in the epineurium

Kohane, D. S., Lipp, M. M., Kinney, R. C., et al. (2001) · Journal of Biomedical Materials Research · doi:10.1002/jbm.1261 · Cited by 99 · see citing works

Tetrodotoxin for prolonged local anesthesia with minimal myotoxicity

Padera, R. F., Tse, J. Y., Bellas, E., et al. (2006) · Muscle & Nerve · doi:10.1002/mus.20618 · Cited by 79 · see citing works

Peritoneal application of chitosan and UV‐cross‐linkable chitosan

Yeo, Y., Burdick, J. A., Highley, C. B., Marini, R. P., Langer, R., & Kohane, D. S. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30740 · Cited by 70 · see citing works

pH-Triggered Microparticles for Peptide Vaccination

Haining, W. N., Anderson, D. G., Little, S. R., von Berwelt-Baildon, M. S., Cardoso, A. A., Alves, P. M. S., Kosmatopoulos, K., Nadler, L. M., Langer, R., & Kohane, D. S. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.4.2578 · Cited by 68 · see citing works

Prevention of peritoneal adhesions with an in situ cross-linkable hyaluronan hydrogel delivering budesonide

Yeo, Y., Adil, M. M., Bellas, E., et al. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2007.04.016 · Cited by 65 · see citing works

Prolonged duration local anesthesia with lipid–protein–sugar particles containing bupivacaine and dexamethasone

Colombo, G., Padera, R. F., Langer, R., et al. (2005) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30443 · Cited by 61 · see citing works

Sciatic Nerve Blockade with Lipid-Protein-Sugar Particles Containing Bupivacaine

Kohane, D. S., Lipp, M. M., Kinney, R. C., et al. (2000) · Pharmaceutical Research · doi:10.1023/a:1026470831256 · Cited by 58 · see citing works

Peritoneal adhesion prevention with an in situ cross-linkable hyaluronan gel containing tissue-type plasminogen activator in a rabbit repeated-injury model

Yeo, Y., Bellas, E., Highley, C. B., et al. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.04.033 · Cited by 53 · see citing works

Inhibition of postsurgical adhesions in a standardized rabbit model: intraperitoneal treatment with tissue plasminogen activator.

Orita, H., Fukasawa, M., Girgis, W., et al. (1991) · PubMed · Cited by 50 · see citing works

The state-of-the-art in predictive toxicogenomics.

Fielden, M. R., & Kolaja, K. L. (2006) · PubMed · Cited by 47 · see citing works

Effect of Chemical Permeation Enhancers on Nerve Blockade

Simons, E. J., Bellas, E., Lawlor, M. W., et al. (2008) · Molecular Pharmaceutics · doi:10.1021/mp800167a · Cited by 46 · see citing works

Lipid–sugar particles for intracranial drug delivery: safety and biocompatibility

Kohane, D. S., Plesnila, N., Thomas, S. S., et al. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02878-0 · Cited by 39 · see citing works

Polymers for intracellular delivery of nucleic acids

Little, S. R., & Kohane, D. S. (2007) · Journal of Materials Chemistry · doi:10.1039/b712930k · Cited by 33 · see citing works

Effect of excipient composition on the biocompatibility of bupivacaine‐containing microparticles at the sciatic nerve

Colombo, G., Langer, R., & Kohane, D. S. (2004) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.20074 · Cited by 26 · see citing works

Rheological blends for drug delivery. II. Prolongation of nerve blockade, biocompatibility, and in vitro–in vivo correlations

Hoare, T. R., Bellas, E., Zurakowski, D., et al. (2009) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32420 · Cited by 20 · see citing works

Engineered Nanoparticles for Drug Delivery in Cancer Therapy

Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164 · see citing works

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

Singh, A. P., Biswas, A., Shukla, A., & Maiti, P. (2019) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-019-0068-3 · Cited by 645 · see citing works

Metal Nanoparticles in Alzheimer’s Disease

Behera, A., Sa, N., Pradhan, S. P., Swain, S., & Sahu, P. K. (2023) · Journal of Alzheimer's Disease Reports · doi:10.3233/adr-220112 · Cited by 50 · see citing works

Current Trends in Biomaterial Coatings

Mikhalovsky, S. V., Santin, M., Mikhalovska, L. I., et al. (2003) · Springer eBooks · doi:10.1007/978-94-010-0157-1_2 · Cited by 2 · see citing works

Biocompatibility of implantable antennas: Design and performance considerations

Psathas, K. A., Kiourti, A., & Nikita, K. S. (2014) · doi:10.1109/eucap.2014.6902083 · Cited by 16 · see citing works

Long-term biocompatibility, chemistry, and function of microencapsulated pancreatic islets

de Vos, P., van Hoogmoed, C. G., van Zanten, J., Netter, S., STRUBBE, J. H., & Busscher, H. J. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00319-8 · Cited by 132 · see citing works

New Approaches for Biocompatibility Testing Using Cell Culture

Doillon, C. J., & Cameron, K. (1990) · The International Journal of Artificial Organs · doi:10.1177/039139889001300812 · Cited by 7 · see citing works

Relationships between bulk and surface structure and biomaterial biocompatibility

Bertoluzza, A., Morelli, M. A., & Tinti, A. (1992) · Springer eBooks · doi:10.1007/978-94-011-2896-4_23