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Mechanochemistry: opportunities for new and cleaner synthesis
Open accessAbstract
The aim of this critical review is to provide a broad but digestible overview of mechanochemical synthesis, i.e. reactions conducted by grinding solid reactants together with no or minimal solvent. Although mechanochemistry has historically been a sideline approach to synthesis it may soon move into the mainstream because it is increasingly apparent that it can be practical, and even advantageous, and because of the opportunities it provides for developing more sustainable methods. Concentrating on recent advances, this article covers industrial aspects, inorganic materials, organic synthesis, cocrystallisation, pharmaceutical aspects, metal complexes (including metal-organic frameworks), supramolecular aspects and characterization methods. The historical development, mechanistic aspects, limitations and opportunities are also discussed (314 references).
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Cites
Cyclodextrins in drug delivery: An updated review
Challa, R., Ahuja, A., Ali, J., & Khar, R. K. (2005) · AAPS PharmSciTech · doi:10.1208/pt060243 · Cited by 1,215
Perspective on Solvent Use in the Pharmaceutical Industry
Constable, D. J. C., Jimenez-Gonzalez, C., & Henderson, R. K. (2007) · Organic Process Research & Development · doi:10.1021/op060170h · Cited by 744
Cited by
Green and sustainable solvents in chemical processes
Clarke, C. J., Tu, W.-C., Levers, O., Bröhl, A., & Hallett, J. P. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00571 · Cited by 2,071
High-entropy materials for catalysis: A new frontier
Sun, Y., & Dai, S. (2021) · Science Advances · doi:10.1126/sciadv.abg1600 · Cited by 942
Single atom electrocatalysts supported on graphene or graphene-like carbons
Fei, H., Dong, J., Chen, D., Hu, T., Duan, X., Shakir, I., Huang, Y., & Duan, X. (2019) · Chemical Society Reviews · doi:10.1039/c9cs00422j · Cited by 673
Alternative energy input: mechanochemical, microwave and ultrasound-assisted organic synthesis
Baig, R. B. N., & Varma, R. S. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15204a · Cited by 587
Mechanochemistry and organic synthesis: from mystical to practical
Andersen, J., & Mack, J. (2018) · Green Chemistry · doi:10.1039/c7gc03797j · Cited by 580
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Metadata
- Authors
- James, S. L., Adams, C. J., Bolm, C., Braga, D., Collier, P., Friščić, T., Grepioni, F., Harris, K. D. M., Hyett, G., Jones, W., Krebs, A., Mack, J., Maini, L., Orpen, A. G., Parkin, I. P., Shearouse, W. C., Steed, J. W., & Waddell, D. C.
- Venue
- Chem. Soc. Rev.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2012
- Volume
- 41
- Issue
- 1
- Pages
- 413-447
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2159582789
- Cited by
- 3,056
- References
- 2
- FWCI
- 6.14
- Type
- journal article
- Language
- en
- Open access
- green
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- James, S. L., Adams, C. J., Bolm, C., Braga, D., Collier, P., Friščić, T., Grepioni, F., Harris, K. D. M., Hyett, G., Jones, W., Krebs, A., Mack, J., Maini, L., Orpen, A. G., Parkin, I. P., Shearouse, W. C., Steed, J. W., & Waddell, D. C. (2012). Mechanochemistry: opportunities for new and cleaner synthesis. Chem. Soc. Rev. https://doi.org/10.1039/c1cs15171a
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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