Evaluation of a tape-stripping technique for measuring dermal exposure to pyrene and benzo(a)pyrene
Abstract
Epidemiological studies have shown an increased incidence of cancer among workers occupationally exposed to polycyclic aromatic hydrocarbons (PAHs). As the dermal route is considered important for exposure to PAHs in the workplace, the aim of this study was to develop and evaluate a tape-stripping technique for monitoring dermal exposure to pyrene and benzo(a)pyrene. The tape-stripping method was evaluated by applying different concentrations of pyrene and benzo(a)pyrene directly onto tape strips (spiked tapes), clean glass plates, and on the skin of five volunteers. The glass plates were stripped using a single strip of tape and the skin of the volunteers was stripped with five consecutive strips of tape after 0 and 30 minutes. The method was also tested on five chimney sweeps at three exposure sites. High-performance liquid chromatography with fluorescence detection was employed for the quantification of pyrene and benzo(a)pyrene. The mean recovery from the spiked tapes was 97% for pyrene and 93% for benzo(a)pyrene. The mean overall recovery from the glass plates was 88% and 76% for pyrene and 88 and 85% for benzo(a)pyrene. The recovery from human skin was 70% and 63% for pyrene and 60 and 54% for benzo(a)pyrene, after 0 and 30 minutes, respectively. A concentration gradient was clearly detected between the five consecutive strips. Detectable amounts of pyrene and benzo(a)pyrene were found on all chimney sweeps at all exposure sites. This method can thus be used to detect and quantify dermal exposure to pyrene and benzo(a)pyrene. The results also show that pyrene and benzo(a)pyrene may be taken up by the skin.
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Dermal uptake is a direct route of pollutant contamination.
“These studies all indicate that dermal uptake is a direct route of pollutant contamination (Fig. 1).”
From The impact of airborne pollution on skin (2019) · cites this paper as [22]
Cites
Boström, C.-E., Gerde, P., Hanberg, A., Jernström, B., Johansson, C., Kyrklund, T., Rannug, A., Törnqvist, M., Victorin, K., & Westerholm, R. N. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.110-1241197 · Cited by 1,701 · see citing works
Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons
Boffetta, P., Jourenkova, N., & Gustavsson, P. (1997) · Cancer Causes & Control · doi:10.1023/a:1018465507029 · Cited by 1,039 · see citing works
Boström, C.-E., Gerde, P., Hanberg, A., Jernström, B., Johansson, C., Kyrklund, T., Rannug, A., Törnqvist, M., Victorin, K., & Westerholm, R. N. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.02110s3451 · Cited by 848 · see citing works
Bosetti, C., Boffetta, P., & Vecchia, C. L. (2006) · Annals of Oncology · doi:10.1093/annonc/mdl172 · Cited by 306 · see citing works
Fluhr, J. W., Feingold, K. R., & Elias, P. M. (2006) · Experimental Dermatology · doi:10.1111/j.1600-0625.2006.00437.x · Cited by 262 · see citing works
An Assessment of Occupational Exposure to Polycyclic Aromatic Hydrocarbons in the UK
Unwin, J., Cocker, J., Scobbie, E., et al. (2006) · The Annals of Occupational Hygiene · doi:10.1093/annhyg/mel010 · Cited by 199 · see citing works
DERMAL EXPOSURE ASSESSMENT TECHNIQUES
Fenske, R. A. (1993) · The Annals of Occupational Hygiene · doi:10.1093/annhyg/37.6.687 · Cited by 179 · see citing works
Use of patches and whole body sampling for the assessment of dermal exposure
Soutar, A. (2000) · The Annals of Occupational Hygiene · doi:10.1016/s0003-4878(00)00043-0 · Cited by 95 · see citing works
Rihs, H., Pesch, B., Kappler, M., et al. (2005) · Toxicology Letters · doi:10.1016/j.toxlet.2005.02.012 · Cited by 66 · see citing works
Dermal Exposure to Polycyclic Aromatic Hydrocarbons among Road Pavers
Väänänen, V., Hämeilä, M., Kalliokoski, P., NYKYRI, E., & Heikkilä, P. (2005) · The Annals of Occupational Hygiene · doi:10.1093/annhyg/meh094 · Cited by 65 · see citing works
Determination of Keratin Protein in a Tape-stripped Skin Sample from Jet Fuel Exposed Skin
Chao, Y.-C. E., & Nylander‐French, L. A. (2004) · The Annals of Occupational Hygiene · doi:10.1093/annhyg/meg081 · Cited by 63 · see citing works
Dermal Exposure and Urinary 1-Hydroxypyrene among Asphalt Roofing Workers
McClean, M. D., Rinehart, R. D., Sapkota, A., Cavallari, J. M., & Herrick, R. F. (2007) · Journal of Occupational and Environmental Hygiene · doi:10.1080/15459620701334756 · Cited by 59 · see citing works
A tape-stripping method for measuring dermal exposure to multifunctional acrylates
Nylander‐French, L. A. (2000) · The Annals of Occupational Hygiene · doi:10.1016/s0003-4878(00)00022-3 · Cited by 53 · see citing works
Dermal exposure to polycyclic aromatic hydrocarbons in asphalt workers
Fustinoni, S., Campo, L., Cirla, P. E., Martinotti, I., Buratti, M., Longhi, O., Foà, V., & Bertazzi, P. (2010) · Occupational and Environmental Medicine · doi:10.1136/oem.2009.050344 · Cited by 43 · see citing works
Dermal and Inhalation Exposure to Methylene Bisphenyl Isocyanate (MDI) in Iron Foundry Workers
Liljelind, I., Norberg, C., Egelrud, L., Westberg, H., Eriksson, K., & Nylander‐French, L. A. (2009) · The Annals of Occupational Hygiene · doi:10.1093/annhyg/mep067 · Cited by 42 · see citing works
Self-citationTape-strip sampling for measuring dermal exposure to 1,6-hexamethylene diisocyanate
Fent, K. W., Jayaraj, K., Gold, A. R., et al. (2006) · Scandinavian Journal of Work Environment & Health · doi:10.5271/sjweh.1003 · Cited by 37 · see citing works
Estimating Dermal Exposure to Jet Fuel (Naphthalene) Using Adhesive Tape Strip Samples
Mattorano, D., Kupper, L. L., & Nylander‐French, L. A. (2004) · The Annals of Occupational Hygiene · doi:10.1093/annhyg/meh003 · Cited by 35 · see citing works
Identification of dermal exposure pathways in the rubber manufacturing industry
Vermeulen, R. C. H. (2000) · The Annals of Occupational Hygiene · doi:10.1016/s0003-4878(00)00039-9 · Cited by 30 · see citing works
Eriksson, K., Hagström, K., Axelsson, S., et al. (2008) · Journal of Environmental Monitoring · doi:10.1039/b719152a · Cited by 10 · see citing works
Self-citationLiljelind, I., Michel, I., Damm, M., et al. (2007) · The Annals of Occupational Hygiene · doi:10.1093/annhyg/mem015 · Cited by 7 · see citing works
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The impact of airborne pollution on skin
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- Authors
- Kammer, R., Tinnerberg, H., & Eriksson, K.
- Affiliations
- Lund University (SE)
- University Hospital of Umeå (SE)
- Corresponding author
- Kammer, Ronny
- Venue
- Journal of Environmental Monitoring
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2011
- Volume
- 13
- Issue
- 8
- Pages
- 2165
- ISSN
- 1464-0325 (ISSN-L)
- 1464-0333
- OpenAlex
- W2169880256
- Cited by
- 38
- References
- 20
- Citations by year
- 2026: 4 · 2024: 2 · 2022: 3 · 2021: 6 · 2020: 6 · 2019: 6 · 2018: 3 · 2017: 2 · 2016: 2 · 2013: 1 · 2012: 2
- FWCI
- 0.69
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Environmental Monitoring (publishedVersion)
- PubMed (publishedVersion)
- Lund University Publications (Lund University) (submittedVersion)
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Toxic Organic Pollutants Impact
- Health Sciences › Health Professions › Occupational Therapy › Occupational Health and Safety in Workplaces
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Carcinogens and Genotoxicity Assessment
- Keywords
- tape stripping, dermal exposure, pyrene, benzo[a]pyrene, polycyclic aromatic hydrocarbons, occupational exposure, chimney sweeps, exposure monitoring
- MeSH terms
- Adult, Benzo(a)pyrene, Environmental Monitoring, Humans, Middle Aged, Pyrenes, Skin, Occupational Exposure, Limit of Detection
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