The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Graphene-based biosensors for detection of bacteria and their metabolic activities
Open accessAbstract
Graphene, which is a recently discovered single-atom-thick planar sheet of carbon atoms perfectly arranged in a honeycomb lattice, has great potential in biosensing owing to its extraordinary electrical, physical, and optical properties. In this work, we demonstrate a graphene based biosensor to electrically detect E. coli bacteria with high sensitivity and specificity. The large-sized graphene film was grown by chemical vapor deposition and functionalized with anti-E. coliantibodies and passivation layer. Significant conductance increase of the graphene device was observed after exposure to E. coli bacteria at a concentration as low as 10 cfu/mL, while no significant response was triggered by high concentration of the another bacterial strain. In addition, this biosensor was employed to detect the glucose induced metabolic activities of the bound E. coli bacteria in real time. This simple, fast, sensitive, and label-free nanoelectronic biosensor, in principle, could serve as a high throughput platform for detection of any pathogenic bacteria, and for functional studies or screening of antibacterial drugs.
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Cites
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Carbon Nanomaterials in Biosensors: Should You Use Nanotubes or Graphene?
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Label-free immunodetection with CMOS-compatible semiconducting nanowires
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Cited by
Environmental applications of graphene-based nanomaterials
Perreault, F., Fonseca de Faria, A., & Elimelech, M. (2015) · Chemical Society Reviews · doi:10.1039/c5cs00021a · Cited by 1,528
Graphene-based electronic sensors
He, Q., Wu, S., Yin, Z., & Zhang, H. (2012) · Chemical Science · doi:10.1039/c2sc20205k · Cited by 745
Binary metal oxide: advanced energy storage materials in supercapacitors
Zhang, Y., Li, L., Su, H., Huang, W., & Dong, X. (2015) · Journal of Materials Chemistry A · doi:10.1039/c4ta04996a · Cited by 666
Self-citationToxicity studies of six types of carbon nanoparticles in a chicken-embryo model
Kurantowicz, N., Sawosz, E., Halik, G., Strojny, B., Hotowy, A., Grodzik, M., Piast, R., Pasanphan, W., & Chwalibog, A. (2017) · International Journal of Nanomedicine · doi:10.2147/ijn.s131960 · Cited by 39
Metadata
- Authors
- Huang, Y., Dong, X., Liu, Y., Li, L.-J., & Chen, P.
- Venue
- Journal of Materials Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2011
- Volume
- 21
- Issue
- 33
- Pages
- 12358
- ISSN
- 0959-9428 (ISSN-L)
- 1364-5501
- OpenAlex
- W2094971181
- Cited by
- 375
- References
- 38
- FWCI
- 18.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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