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Cited by 548

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Mesoporous silica nanoparticles for bioadsorption, enzyme immobilisation, and delivery carriers

Popat, Amirali, Hartono, Sandy Budi, Stahr, Frances, Liu, Jian, Qiao, Shi Zhang, Qing (Max) Lu, Gao·2011·Nanoscale

Abstract

Mesoporous silica nanoparticles (MSNs) provide a non-invasive and biocompatible delivery platform for a broad range of applications in therapeutics, pharmaceuticals and diagnosis. The creation of smart, stimuli-responsive systems that respond to subtle changes in the local cellular environment are likely to yield long term solutions to many of the current drug/gene/DNA/RNA delivery problems. In addition, MSNs have proven to be promising supports for enzyme immobilisation, enabling the enzymes to retain their activity, affording them greater potential for wide applications in biocatalysis and energy. This review provides a comprehensive summary of the advances made in the last decade and a future outlook on possible applications of MSNs as nanocontainers for storage and delivery of biomolecules. We discuss some of the important factors affecting the adsorption and release of biomolecules in MSNs and review of the cytotoxicity aspects of such nanomaterials. The review also highlights some promising work on enzyme immobilisation using mesoporous silica nanoparticles.

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Metadata

Authors
Popat, A., Hartono, S. B., Stahr, F., Liu, J., Qiao, S. Z., & Qing (Max) Lu, G.
Venue
Nanoscale
Published
2011
Volume
3
Issue
7
Pages
2801
ISSN
  • 2040-3364 (ISSN-L)
  • 2040-3372
OpenAlex
W2168696947
Cited by
548
References
3
FWCI
22.77
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Mesoporous silica nanoparticles for bioadsorption, enzyme immobilisation, and delivery carriers. https://app.cochat.ai/papers/10.1039/c1nr10224a
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Popat, A., Hartono, S. B., Stahr, F., Liu, J., Qiao, S. Z., & Qing (Max) Lu, G. (2011). Mesoporous silica nanoparticles for bioadsorption, enzyme immobilisation, and delivery carriers. Nanoscale. https://doi.org/10.1039/c1nr10224a

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