The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Surface chemistry to minimize fouling from blood-based fluids
Abstract
Upon contact with bodily fluids/tissues, exogenous materials spontaneously develop a layer of proteins on their surface. In the case of biomedical implants and equipment, biological processes with deleterious effects may ensue. For biosensing platforms, it is synonymous with an overwhelming background signal that prevents the detection/quantification of target analytes present in considerably lower concentrations. To address this ubiquitous problem, tremendous efforts have been dedicated over the years to engineer protein-resistant coatings. There is now extensive literature available on stealth organic adlayers able to minimize fouling down to a few ng cm(-2), however from technologically irrelevant single-protein buffered solutions. Unfortunately, few coatings have been reported to present such level of performance when exposed to highly complex proteinaceous, real-world media such as blood serum and plasma, even diluted. Herein, we concisely review the surface chemistry developed to date to minimize fouling from these considerably more challenging blood-based fluids. Adsorption dynamics is also discussed.
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Cites
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Cited by
Zhang, D., Chen, Q., Shi, C., Chen, M., Ma, K., Wan, J., & Liu, R. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202007226 · Cited by 303
Highly Sensitive and Multiplexed Protein Measurements
Cohen, L., & Walt, D. R. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00257 · Cited by 294
Tardy, B. L., Mattos, B. D., Otoni, C. G., Beaumont, M., Majoinen, J., Kämäräinen, T., & Rojas, O. J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01333 · Cited by 267
Nanoplasmonic sensors for biointerfacial science
Jackman, J. A., Rahim Ferhan, A., & Cho, N.-J. (2017) · Chemical Society Reviews · doi:10.1039/c6cs00494f · Cited by 258
Brown, B. N., Haschak, M. J., Lopresti, S. T., & Stahl, E. C. (2017) · Seminars in Immunology · doi:10.1016/j.smim.2017.05.001 · Cited by 55
Metadata
- Authors
- Blaszykowski, C., Sheikh, S., & Thompson, M.
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2012
- Volume
- 41
- Issue
- 17
- Pages
- 5599
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2034529942
- Cited by
- 271
- References
- 101
- FWCI
- 1.17
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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