The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Stimuli-responsive copolymer solution and surface assemblies for biomedical applications
Open accessAbstract
Stimuli-responsive polymeric materials is one of the fastest growing fields of the 21st century, with the annual number of papers published more than quadrupling in the last ten years. The responsiveness of polymer solution assemblies and surfaces to biological stimuli (e.g. pH, reduction-oxidation, enzymes, glucose) and externally applied triggers (e.g. temperature, light, solvent quality) shows particular promise for various biomedical applications including drug delivery, tissue engineering, medical diagnostics, and bioseparations. Furthermore, the integration of copolymer architectures into stimuli-responsive materials design enables exquisite control over the locations of responsive sites within self-assembled nanostructures. The combination of new synthesis techniques and well-defined copolymer self-assembly has facilitated substantial developments in stimuli-responsive materials in recent years. In this tutorial review, we discuss several methods that have been employed to synthesize self-assembling and stimuli-responsive copolymers for biomedical applications, and we identify common themes in the response mechanisms among the targeted stimuli. Additionally, we highlight parallels between the chemistries used for generating solution assemblies and those employed for creating copolymer surfaces.
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Cited by
Kamaly, N., Yameen, B., Wu, J., & Farokhzad, O. C. (2016) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00346 · Cited by 3,070
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
Karimi, M., Ghasemi, A., Sahandi Zangabad, P., Rahighi, R., Moosavi Basri, S. M., Mirshekari, H., Amiri, M., Shafaei Pishabad, Z., Aslani, A., Bozorgomid, M., et al. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00798d · Cited by 1,519
The Smart Drug Delivery System and Its Clinical Potential
Liu, D., Yang, F., Xiong, F., & Gu, N. (2016) · Theranostics · doi:10.7150/thno.14858 · Cited by 1,066
Stimuli-responsive smart gating membranes
Liu, Z., Wang, W., Xie, R., Ju, X.-J., & Chu, L.-Y. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00692a · Cited by 432
Folate-conjugated pH-controllable fluorescent nanomicelles acting as tumor targetable drug carriers
Hao, W., Wang, T., Liu, D., Shang, Y., Zhang, J., Xu, S., & Liu, H. (2017) · Microchimica Acta · doi:10.1007/s00604-017-2255-7 · Cited by 9
Metadata
- Authors
- Kelley, E. G., Albert, J. N. L., Sullivan, M. O., & Epps, III
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2013
- Volume
- 42
- Issue
- 17
- Pages
- 7057
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2079657559
- Cited by
- 295
- References
- 56
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- green
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