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Cited by 295

The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.

Stimuli-responsive copolymer solution and surface assemblies for biomedical applications

Open access
Kelley, Elizabeth G., Albert, Julie N. L., Sullivan, Millicent O., Epps, III, Thomas H.·2013·Chemical Society Reviews

Abstract

Stimuli-responsive polymeric materials is one of the fastest growing fields of the 21st century, with the annual number of papers published more than quadrupling in the last ten years. The responsiveness of polymer solution assemblies and surfaces to biological stimuli (e.g. pH, reduction-oxidation, enzymes, glucose) and externally applied triggers (e.g. temperature, light, solvent quality) shows particular promise for various biomedical applications including drug delivery, tissue engineering, medical diagnostics, and bioseparations. Furthermore, the integration of copolymer architectures into stimuli-responsive materials design enables exquisite control over the locations of responsive sites within self-assembled nanostructures. The combination of new synthesis techniques and well-defined copolymer self-assembly has facilitated substantial developments in stimuli-responsive materials in recent years. In this tutorial review, we discuss several methods that have been employed to synthesize self-assembling and stimuli-responsive copolymers for biomedical applications, and we identify common themes in the response mechanisms among the targeted stimuli. Additionally, we highlight parallels between the chemistries used for generating solution assemblies and those employed for creating copolymer surfaces.

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Metadata

Authors
Kelley, E. G., Albert, J. N. L., Sullivan, M. O., & Epps, III
Venue
Chemical Society Reviews
Published
2013
Volume
42
Issue
17
Pages
7057
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
OpenAlex
W2079657559
Cited by
295
References
56
FWCI
1.35
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Stimuli-responsive copolymer solution and surface assemblies for biomedical applications. https://app.cochat.ai/papers/10.1039/c3cs35512h
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Kelley, E. G., Albert, J. N. L., Sullivan, M. O., & Epps, III. (2013). Stimuli-responsive copolymer solution and surface assemblies for biomedical applications. Chemical Society Reviews. https://doi.org/10.1039/c3cs35512h

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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