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Human exposure to aluminium
Open accessAbstract
Human activities have circumvented the efficient geochemical cycling of aluminium within the lithosphere and therewith opened a door, which was previously only ajar, onto the biotic cycle to instigate and promote the accumulation of aluminium in biota and especially humans. Neither these relatively recent activities nor the entry of aluminium into the living cycle are showing any signs of abating and it is thus now imperative that we understand as fully as possible how humans are exposed to aluminium and the future consequences of a burgeoning exposure and body burden. The aluminium age is upon us and there is now an urgent need to understand how to live safely and effectively with aluminium.
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“The Al ion has no physiological role in metabolic processes (Exley and House, 2011) but it can be a metallic toxicant to humans and animals (Becaria et al., 2002) when there is high body burden of the metal after natural or unnatural exposure (Exley, 2013).”
From Aluminium toxicosis: a review of toxic actions and effects (2019) · cites this paper as Exley, 2013
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“Toxic effects of Al arise mainly from its pro-oxidant activity which results in oxidative stress, free radical attack and oxidation of cellular proteins and lipids (Exley, 2013).”
From Aluminium toxicosis: a review of toxic actions and effects (2019) · cites this paper as Exley, 2013
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Urinary Excretion of Aluminium and Silicon in Secondary Progressive Multiple Sclerosis
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Self-citationAn aluminium adjuvant in a vaccine is an acute exposure to aluminium
Exley, C. (2019) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2019.09.010 · Cited by 29
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The Mobilization of Aluminum into the Biosphere
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Metadata
- Authors
- Exley, C.
- Affiliations
- Keele University (GB)
- Corresponding author
- Exley, Christopher
- ORCID
- Exley, Christopher
- Venue
- Environ. Sci.: Processes Impacts
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2013
- Volume
- 15
- Issue
- 10
- Pages
- 1807-1816
- ISSN
- 2050-7887 (ISSN-L)
- 2050-7895
- OpenAlex
- W2098844459
- Cited by
- 382
- References
- 93
- Citations by year
- 2026: 30 · 2025: 25 · 2024: 38 · 2023: 34 · 2022: 28 · 2021: 43 · 2020: 41 · 2019: 37 · 2018: 24 · 2017: 17 · 2016: 21 · 2015: 15 · 2014: 25 · 2013: 3
- FWCI
- 2.29
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- Environmental Science Processes & Impacts (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Aluminum toxicity and tolerance in plants and animals
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Keywords
- aluminum exposure, human body burden, environmental contamination
- MeSH terms
- Aluminum, Body Burden, Environmental Exposure, Environmental Pollutants, Humans
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