Friedel–Crafts alkylation of heteroarenes and arenes with indolyl alcohols for construction of 3,3-disubstituted oxindoles
Abstract
An intriguing camphorsulfonic acid catalyzed Friedel–Crafts alkylation of arenes with indolyl alcohols has been developed featuring mild reaction conditions, wide substrate scope and high yields.
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- Authors
- Wang, X., Liu, J., Xu, L., Hao, Z., Wang, L., & Xiao, J.
- Affiliations
- Qingdao University of Science and Technology (CN)
- Qingdao Agricultural University (CN)
- Corresponding author
- Wang, Liang
- Xiao, Jian
- Venue
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2015
- Volume
- 5
- Issue
- 123
- Pages
- 101713-101717
- ISSN
- 2046-2069 (ISSN-L)
- OpenAlex
- W2173779332
- Cited by
- 28
- References
- 80
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 1 · 2021: 5 · 2020: 3 · 2018: 5 · 2017: 5 · 2016: 3
- FWCI
- 1.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- RSC Advances (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Synthesis of Indole Derivatives
- Physical Sciences › Chemistry › Spectroscopy › Organic and Inorganic Chemical Reactions
- Physical Sciences › Chemistry › Organic Chemistry › Synthesis and Reactivity of Heterocycles
- Keywords
- Friedel-Crafts alkylation, heteroarenes, aromatic hydrocarbons, 3,3-disubstituted oxindoles, indole synthesis, Lewis acid catalysis
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