Surface modification and endothelialization of polyurethane for vascular tissue engineering applications: a review
Abstract
This review summarizes the surface modification and endothelialization of polyurethane for vascular tissue engineering applications, including recent developments and strategies.
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Other agents including fucoidan, laminin, hyaluronic acid, chondroitin sulfate, type 1 collagen, and VEGF have been used to improve endothelialization on the surface of nano and metal stents and thin tissues such as heart valve and blood vessels.
“Other agents, including fucoidan (FU), laminin, hyaluronic acid (HA), chondroitin sulfate, type 1 collagen, and vascular endothelial growth factor (VEGF), have been used to improve endothelialization on the surface of nano and metal stents as well as thin tissues such as heart valve and blood vessels [231,234].”
From Liver tissue engineering using decellularized scaffolds: Current progress, challenges, and opportunities (2024) · cites this paper as [234]
EPCs are circulating cells in peripheral blood originating from the bone marrow, representing approximately 0.01% of all blood mononuclear cells, with some cells residing in adipose tissue of adults.
“Endothelial progenitor cells (EPCs) are circulating cells in peripheral blood originating from the bone marrow, representing approximately 0.01 % of all blood mononuclear cells, with some cells residing in the adipose tissue of adults [234].”
From Liver tissue engineering using decellularized scaffolds: Current progress, challenges, and opportunities (2024) · cites this paper as [234]
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Self-citation
- Authors
- Adipurnama, I., Yang, M.-C., Ciach, T., & Butruk-Raszeja, B.
- Affiliations
- National Taiwan University of Science and Technology (TW)
- Warsaw University of Technology (PL)
- Corresponding author
- Yang, Ming-Chien
- Venue
- Biomaterials Science
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2017
- Volume
- 5
- Issue
- 1
- Pages
- 22-37
- ISSN
- 2047-4830 (ISSN-L)
- 2047-4849
- OpenAlex
- W2562475264
- Cited by
- 179
- References
- 123
- Citations by year
- 2026: 11 · 2025: 17 · 2024: 15 · 2023: 19 · 2022: 23 · 2021: 19 · 2020: 27 · 2019: 20 · 2018: 16 · 2017: 12
- FWCI
- 0.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biomaterials Science (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Food and Drug Administration
- Topics
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Keywords
- polyurethane, vascular grafts, endothelialization, surface modification, hemocompatibility, restenosis, thrombus formation, polyethylene glycol, zwitterion, polysaccharides, peptide coating, biomolecules, gene delivery, bioactive polymers, graft patency
- MeSH terms
- Blood Vessel Prosthesis, Cell Adhesion, Humans, Polyurethanes, Thrombosis, Tissue Engineering, Endothelial Cells
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