Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment

Acylsulfonamide‐Functionalized Zwitterionic Gold Nanoparticles for Enhanced Cellular Uptake at Tumor pH

Mizuhara, T., Saha, K., Moyano, D. F., Kim, C. S., Yan, B., Kim, Y., & Rotello, V. M. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201411615 · Cited by 182

Poly(carboxybetaine) nanomaterials enable long circulation and prevent polymer-specific antibody production

Yang, W., Liu, S., Bai, T., Keefe, A. J., Zhang, L., Ella-Menye, J.-R., Li, Y., & Jiang, S. (2014) · Nano Today · doi:10.1016/j.nantod.2014.02.004 · Cited by 181

Bromelain Surface Modification Increases the Diffusion of Silica Nanoparticles in the Tumor Extracellular Matrix

Parodi, A., Haddix, S. G., Taghipour, N., Scaria, S., Taraballi, F., Cevenini, A., Yazdi, I. K., Corbo, C., Palomba, R., Khaled, S. Z., et al. (2014) · ACS Nano · doi:10.1021/nn502807n · Cited by 181

Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature

Backer, M. V., Gaynutdinov, T. I., Patel, V., Bandyopadhyaya, A. K., Thirumamagal, B. T. S., Tjarks, W., Barth, R. F., Claffey, K., & Backer, J. M. (2005) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-05-0161 · Cited by 180

In Vivo Tumor Vasculature Targeting of CuS@MSN Based Theranostic Nanomedicine

Chen, F., Hong, H., Goel, S., Graves, S. A., Orbay, H., Ehlerding, E. B., Shi, S., Theuer, C. P., Nickles, R. J., & Cai, W. (2015) · ACS Nano · doi:10.1021/nn507241v · Cited by 175

A Preloaded Amorphous Calcium Carbonate/Doxorubicin@Silica Nanoreactor for pH‐Responsive Delivery of an Anticancer Drug

Zhao, Y., Luo, Z., Li, M., Qu, Q., Ma, X., Yu, S., & Zhao, Y. (2015) · Angewandte Chemie · doi:10.1002/ange.201408510 · Cited by 173

Distinct Cytokine Profiles of Neonatal Natural Killer T Cells after Expansion with Subsets of Dendritic Cells

Kadowaki, N., Antonenko, S., Ho, S., Rissoan, M.-C., Soumelis, V., Porcelli, S. A., Lanier, L. L., & Liu, Y.-J. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.10.1221 · Cited by 172

The application of mesoporous silica nanoparticle family in cancer theranostics

Feng, Y., Panwar, N., Tng, D. J. H., Tjin, S. C., Wang, K., & Yong, K.-T. (2016) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2016.04.019 · Cited by 171

Tumour-associated macrophages and cancer

Cook, J., & Hagemann, T. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.05.017 · Cited by 165

Targeting Vascular Pericytes in Hypoxic Tumors Increases Lung Metastasis via Angiopoietin-2

Keskin, D., Kim, J., Cooke, V. G., Wu, C.-C., Sugimoto, H., Gu, C., De Palma, M., Kalluri, R., & LeBleu, V. S. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.01.035 · Cited by 165

Facile Generation of Tumor‐pH‐Labile Linkage‐Bridged Block Copolymers for Chemotherapeutic Delivery

Sun, C., Liu, Y., Du, J., Cao, Z., Xu, C., & Wang, J. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201509507 · Cited by 165

Engineered Hybrid Nanoparticles for On-Demand Diagnostics and Therapeutics

Nguyen, K. T., & Zhao, Y. (2015) · Accounts of Chemical Research · doi:10.1021/acs.accounts.5b00316 · Cited by 165

Heterogeneity of the tumor vasculature: the need for new tumor blood vessel type-specific targets

Nagy, J. A., & Dvorak, H. F. (2012) · Clinical & Experimental Metastasis · doi:10.1007/s10585-012-9500-6 · Cited by 163

Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo

Som, A., Raliya, R., Tian, L., Akers, W., Ippolito, J. E., Singamaneni, S., Biswas, P., & Achilefu, S. (2016) · Nanoscale · doi:10.1039/c5nr06162h · Cited by 162

Self-Monitoring Artificial Red Cells with Sufficient Oxygen Supply for Enhanced Photodynamic Therapy

Luo, Z., Zheng, M., Zhao, P., Chen, Z., Siu, F., Gong, P., Gao, G., Sheng, Z., Zheng, C., Ma, Y., et al. (2016) · Scientific Reports · doi:10.1038/srep23393 · Cited by 159

Targeting dendritic cells in lymph node with an antigen peptide-based nanovaccine for cancer immunotherapy

Qian, Y., Jin, H., Qiao, S., Dai, Y., Huang, C., Lu, L., Luo, Q., & Zhang, Z. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.05.008 · Cited by 159

VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo

Gosk, S., Moos, T., Gottstein, C., & Bendas, G. (2008) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2007.12.021 · Cited by 158

A Peptide‐Network Weaved Nanoplatform with Tumor Microenvironment Responsiveness and Deep Tissue Penetration Capability for Cancer Therapy

Liu, Y., Zhang, D., Qiao, Z., Qi, G., Liang, X., Chen, X., & Wang, H. (2015) · Advanced Materials · doi:10.1002/adma.201501502 · Cited by 157

pHLIP peptide targets nanogold particles to tumors

Yao, L., Daniels, J., Moshnikova, A., Kuznetsov, S., Ahmed, A., Engelman, D. M., Reshetnyak, Y. K., & Andreev, O. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1219665110 · Cited by 156

Enhancing Photodynamic Therapy Efficacy by Using Fluorinated Nanoplatform

Que, Y., Liu, Y., Tan, W., Feng, C., Shi, P., Li, Y., & Huang, X. (2016) · ACS Macro Letters · doi:10.1021/acsmacrolett.5b00935 · Cited by 155

Development of Novel Tumor‐Targeted Theranostic Nanoparticles Activated by Membrane‐Type Matrix Metalloproteinases for Combined Cancer Magnetic Resonance Imaging and Therapy

Ansari, C., Tikhomirov, G. A., Hong, S. H., Falconer, R. A., Loadman, P. M., Gill, J. H., Castaneda, R., Hazard, F. K., Tong, L., Lenkov, O. D., et al. (2013) · Small · doi:10.1002/smll.201301456 · Cited by 154

Mammalian Secreted Phospholipases A2 and Their Pathophysiolo-gical Significance in Inflammatory Diseases

Touqui, L., & Alaoui-El-Azher, M. (2001) · Current Molecular Medicine · doi:10.2174/1566524013363258 · Cited by 151

Tumor‐derived macrophage migration inhibitory factor modulates the biology of head and neck cancer cells via neutrophil activation

Dumitru, C. A., Gholaman, H., Trellakis, S., Bruderek, K., Dominas, N., Gu, X., Bánkfalvi, Á., Whiteside, T. L., Lang, S., & Brandau, S. (2011) · International Journal of Cancer · doi:10.1002/ijc.25991 · Cited by 146

VEGF121-Conjugated Mesoporous Silica Nanoparticle: A Tumor Targeted Drug Delivery System

Goel, S., Chen, F., Hong, H., Valdovinos, H. F., Hernandez, R. T., Shi, S., Barnhart, T. E., & Cai, W. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am506849p · Cited by 136

Nanomedicine : A Great First Year And, with Your Help, A Bright Future Ahead

Martin, C. R. (2007) · Nanomedicine · doi:10.2217/17435889.2.3.265 · Cited by 130

Drug delivery to macrophages: Challenges and opportunities

Pei, Y., & Yeo, Y. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.12.014 · Cited by 129

Extracellular Matrix of Ovarian Tumors

Ricciardelli, C., & Rodgers, R. J. (2006) · Seminars in Reproductive Medicine · doi:10.1055/s-2006-948556 · Cited by 128

Spatiotemporal Targeting of a Dual-Ligand Nanoparticle to Cancer Metastasis

Doolittle, E., Peiris, P. M., Doron, G., Goldberg, A. L., Tucci, S. T., Rao, S. P., Shah, S., Sylvestre, M., Govender, P., Turan, O., et al. (2015) · ACS Nano · doi:10.1021/acsnano.5b01552 · Cited by 125

pH-responsive and charge shielded cationic micelle of poly( l -histidine)- block -short branched PEI for acidic cancer treatment

Hu, J., Miura, S., Na, K., & Bae, Y. H. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.08.007 · Cited by 123

Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles

Pittella, F., Miyata, K., Maeda, Y., Suma, T., Watanabe, S. T., Chen, Q., Christie, R. J., Osada, K., Nishiyama, N., & Kataoka, K. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.05.005 · Cited by 120

Heterogeneity of tumor endothelial cells and drug delivery

Hida, K., Maishi, N., Sakurai, Y., Hida, Y., & Harashima, H. (2015) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.11.008 · Cited by 120

Molecular targeting of liposomal nanoparticles to tumor microenvironment

Zhao, G., & Rodriguez, L. B. (2012) · International Journal of Nanomedicine · doi:10.2147/ijn.s37859 · Cited by 119

Applications of Nitroimidazole In Vivo Hypoxia Imaging in Ischemic Stroke

Takasawa, M., Moustafa, R. R., & Baron, J. (2008) · Stroke · doi:10.1161/strokeaha.107.485938 · Cited by 118

VEGF-targeted magnetic nanoparticles for MRI visualization of brain tumor

Abakumov, M. A., Nukolova, N. V., Sokolsky‐Papkov, M., Shein, S. A., Sandalova, T., Vishwasrao, H. M., Grinenko, N. F., Gubskiy, I. L., Abakumov, A. M., Kabanov, A. V., et al. (2015) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2014.12.011 · Cited by 116

The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine

Alshamsan, A., Hamdy, S. I., Samuel, J., El‐Kadi, A. O. S., Lavasanifar, A., & Uludağ, H. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.11.003 · Cited by 114

Proteases in cancer drug delivery

Vandooren, J., Opdenakker, G., Loadman, P. M., & Edwards, D. R. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2015.12.020 · Cited by 114

Biomimetic carriers mimicking leukocyte plasma membrane to increase tumor vasculature permeability

Palomba, R., Parodi, A., Evangelopoulos, M., Acciardo, S., Corbo, C., Rosa, E. D., Yazdi, I. K., Scaria, S., Molinaro, R., Furman, N. E. T., et al. (2016) · Scientific Reports · doi:10.1038/srep34422 · Cited by 114

Zwitterionic polymer-protein conjugates reduce polymer-specific antibody response

Liu, S., & Jiang, S. (2016) · Nano Today · doi:10.1016/j.nantod.2016.05.006 · Cited by 112

A Novel Strategy through Combining iRGD Peptide with Tumor-Microenvironment-Responsive and Multistage Nanoparticles for Deep Tumor Penetration

Cun, X., Chen, J., Ruan, S., Zhang, L., Wan, J., He, Q., & Gao, H. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b09391 · Cited by 109

Engineered materials for cancer immunotherapy

Cheung, A. S., & Mooney, D. J. (2015) · Nano Today · doi:10.1016/j.nantod.2015.06.007 · Cited by 108

Nicotinamide can lower tumor interstitial fluid pressure: mechanistic and therapeutic implications.

Lee, I., Boucher, Y., & Jain, R. K. (1992) · PubMed · Cited by 105

Prevention of Abdominal Aortic Aneurysm Progression by Targeted Inhibition of Matrix Metalloproteinase Activity With Batimastat-Loaded Nanoparticles

Nosoudi, N., Nahar-Gohad, P., Sinha, A., Chowdhury, A., Gerard, P., Carsten, C. G., Gray, B. H., & Vyavahare, N. R. (2015) · Circulation Research · doi:10.1161/circresaha.115.307207 · Cited by 103

Reversibly switchable polymer with cationic/zwitterionic/anionic behavior through synergistic protonation and deprotonation

Sundaram, H. S., Ella‐Menye, J., Brault, N. D., Shao, Q., & Jiang, S. (2013) · Chemical Science · doi:10.1039/c3sc52233d · Cited by 101

Hypoxia-Activated Prodrugs in Cancer Therapy: Progress to the Clinic

Denny, W. A. (2010) · Future Oncology · doi:10.2217/fon.10.1 · Cited by 100

Mesenchymal stem cell signaling in cancer progression

Torsvik, A., & Bjerkvig, R. (2013) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2012.03.005 · Cited by 100

Abrogating Drug Resistance in Malignant Peripheral Nerve Sheath Tumors by Disrupting Hyaluronan-CD44 Interactions with Small Hyaluronan Oligosaccharides

Slomiany, M. G., Dai, L., Bomar, P. A., Knackstedt, T., Kranc, D. A., Tolliver, L. B., Maria, B. L., & Toole, B. P. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0143 · Cited by 99

Hydrophobic interaction mediating self-assembled nanoparticles of succinobucol suppress lung metastasis of breast cancer by inhibition of VCAM-1 expression

Cao, H., Zhang, Z., Zhao, S., He, X., Yu, H., Yin, Q., Zhang, Z., Gu, W., Chen, L., & Li, Y. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.01.015 · Cited by 95

Newer nanoparticles in hyperthermia treatment and thermometry

Sharma, R. D., & J.Chen, C. (2008) · Journal of Nanoparticle Research · doi:10.1007/s11051-008-9548-z · Cited by 95

Hybrid Collagenase Nanocapsules for Enhanced Nanocarrier Penetration in Tumoral Tissues

Villegas, M. R., Baeza, A., & Vallet‐Regí, M. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b07116 · Cited by 95

Tumor‐Microenvironment‐Adaptive Nanoparticles Codeliver Paclitaxel and siRNA to Inhibit Growth and Lung Metastasis of Breast Cancer

Tang, S., Meng, Q., Sun, H., Su, J., Yin, Q., Zhang, Z., Yu, H., Chen, L., Chen, Y., Gu, W., et al. (2016) · Advanced Functional Materials · doi:10.1002/adfm.201601703 · Cited by 94

Nanoparticle therapeutics: Technologies and methods for overcoming cancer

Cerqueira, B. B. S., Lasham, A., Shelling, A. N., & Al‐Kassas, R. (2015) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2015.10.007 · Cited by 93

pHLIP®-mediated delivery of PEGylated liposomes to cancer cells

Yao, L., Daniels, J., Wijesinghe, D., Andreev, O. A., & Reshetnyak, Y. K. (2013) · Journal of Controlled Release · doi:10.1016/j.jconrel.2013.01.037 · Cited by 93

Non‐Fouling Character of Poly[2‐(methacryloyloxy)ethyl Phosphorylcholine]‐Modified Gold Surfaces Fabricated by the ‘Grafting to’ Method: Comparison of its Protein Resistance with Poly(ethylene glycol)‐Modified Gold Surfaces

Yoshimoto, K., Hirase, T., Madsen, J., Armes, S. P., & Nagasaki, Y. (2009) · Macromolecular Rapid Communications · doi:10.1002/marc.200900484 · Cited by 92

Myeloid‐Derived Suppressor Cells and Therapeutic Strategies in Cancer

Katoh, H., & Watanabe, M. (2015) · Mediators of Inflammation · doi:10.1155/2015/159269 · Cited by 91

Proteolytic Surface Functionalization Enhancesin VitroMagnetic Nanoparticle Mobility through Extracellular Matrix

Kuhn, S., Finch, S. K., Hallahan, D. E., & Giorgio, T. D. (2006) · Nano Letters · doi:10.1021/nl052241g · Cited by 88

B cells and their mediators as targets for therapy in solid tumors

Gunderson, A. J., & Coussens, L. M. (2013) · Experimental Cell Research · doi:10.1016/j.yexcr.2013.03.005 · Cited by 82

Strategies for triggered drug release from tumor targeted liposomes

Blenke, E. O., Mastrobattista, E., & Schiffelers, R. M. (2013) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2013.805742 · Cited by 80

Methacrylate polymer layers bearing poly(ethylene oxide) and phosphorylcholine side chains as non-fouling surfaces: In vitro interactions with plasma proteins and platelets

Feng, W., Gao, X. Y., McClung, G., Zhu, S., Ishihara, K., & Brash, J. L. (2011) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.06.007 · Cited by 79

Zwitterionic phosphorylcholine as a better ligand for stabilizing large biocompatible gold nanoparticles

Jin, Q., Xu, J., Ji, J., et al. (2008) · Chemical Communications · doi:10.1039/b801959b · Cited by 77

Heterogeneity of tumor endothelial cells

Hida, K., Ohga, N., Akiyama, K., Maishi, N., & Hida, Y. (2013) · Cancer Science · doi:10.1111/cas.12251 · Cited by 76

Dexamethasone reduces the interstitial fluid pressure in a human colon adenocarcinoma xenograft.

Kristjansen, P. E. G., Boucher, Y., & Jain, R. K. (1993) · PubMed · Cited by 76

Targeting pericytes with a PDGF-B aptamer in human ovarian carcinoma models

Lu, C., Shahzad, M. M. K., Moreno‐Smith, M., Lin, Y. G., Jennings, N. B., Allen, J. K., Landen, C. N., Mangala, L. S., Armaiz-Peña, G. N., Schmandt, R. E., et al. (2010) · Cancer Biology & Therapy · doi:10.4161/cbt.9.3.10635 · Cited by 75

Role of the tumor microenvironment in the activity and expression of the p-glycoprotein in human colon carcinoma cells

Lotz, C., Kelleher, D. K., Gaßner, B., Gekle, M., Vaupel, P. W., & Thews, O. (2007) · Oncology Reports · doi:10.3892/or.17.1.239 · Cited by 74

Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment

Dewitte, H., Verbeke, R., Breckpot, K., Smedt, S. C. D., & Lentacker, I. (2014) · Nano Today · doi:10.1016/j.nantod.2014.10.001 · Cited by 72

Matrix metalloproteinase-9 (MMP-9) as an activator of nanosystems for targeted drug delivery in pancreatic cancer

Grünwald, B. T., Vandooren, J., Locatelli, E., Fiten, P., Opdenakker, G., Proost, P., Krüger, A., Lellouche, J., Israel, L. L., Shenkman, L., et al. (2016) · Journal of Controlled Release · doi:10.1016/j.jconrel.2016.08.016 · Cited by 69

The use of HA oligosaccharide-loaded nanoparticles to breach the endogenous hyaluronan glycocalyx for breast cancer therapy

Yang, C., Liu, Y., He, Y., Du, Y., Wang, W., Shi, X., & Gao, F. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.05.036 · Cited by 68

Cancer Targeted Drug Delivery: An Elusive Dream

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Complete amino acid sequence of ananain and a comparison with stem bromelain and other plant cysteine proteases

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Targeted Therapeutic Remodeling of the Tumor Microenvironment Improves an HER-2 DNA Vaccine and Prevents Recurrence in a Murine Breast Cancer Model

Liao, D., Liu, Z., Wrasidlo, W., Luo, Y., Nguyen, G., Chen, T., Xiang, R., & Reisfeld, R. A. (2011) · Cancer Research · doi:10.1158/0008-5472.can-11-1264 · Cited by 64

Protease pretreatment increases the efficacy of adenovirus-mediated gene therapy for the treatment of an experimental glioblastoma model.

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Extracellular matrix, biotensegrity and tumor microenvironment. An update and overview.

Noguera, R., Nieto, O. A., Tadeo, I., Fariñas, F., & Álvaro, T. (2012) · PubMed · doi:10.14670/hh-27.693 · Cited by 57

Methods in pharmacology and toxicology

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Interference with TGF‐β1 and ‐β3 in tumor stroma lowers tumor interstitial fluid pressure independently of growth in experimental carcinoma

Lammerts, E., Roswall, P., Sundberg, C., Gotwals, P. J., Koteliansky, V., Reed, R. K., Heldin, N., & Rubin, K. (2002) · International Journal of Cancer · doi:10.1002/ijc.10722 · Cited by 55

Hypoxia-Sensitive Materials for Biomedical Applications

Yu, J., Zhang, Y., Hu, X., Wright, G., & Gu, Z. (2016) · Annals of Biomedical Engineering · doi:10.1007/s10439-016-1578-6 · Cited by 50

Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine

Sun, W., Ji, W., Hu, Q., Yu, J., Wang, C., Qian, C., Hochu, G. M., & Gu, Z. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.04.011 · Cited by 50

Development of hypoxia-triggered prodrug micelles as doxorubicin carriers for tumor therapy

Liu, H., Zhang, R., Niu, Y., Li, Y., Qiao, C.-M., Weng, J., Li, J., Zhang, X., Xiao, Z., & Zhang, X. (2015) · RSC Advances · doi:10.1039/c4ra14875d · Cited by 48

pH‐Controlled Delivery of Nanoparticles into Tumor Cells

Han, L., Ma, H., Guo, Y., Kuang, Y., He, X., & Jiang, C. (2013) · Advanced Healthcare Materials · doi:10.1002/adhm.201300013 · Cited by 44

Transcriptional dissection of pancreatic tumors engrafted in mice

Martinez-Garcia, R., Juan, D., Rausell, A., Muñoz, M., Baños, N., Menéndez, C., Lopez-Casas, P. P., Rico, D., Valencia, A., & Hidalgo, M. M. (2014) · Genome Medicine · doi:10.1186/gm544 · Cited by 43

Oxygen Nanocarrier for Combined Cancer Therapy: Oxygen‐Boosted ATP‐Responsive Chemotherapy with Amplified ROS Lethality

Zhao, P., Zheng, M., Luo, Z., Fan, X., Sheng, Z., Gong, P., Chen, Z., Zhang, B., Ni, D., Ma, Y., et al. (2016) · Advanced Healthcare Materials · doi:10.1002/adhm.201600121 · Cited by 43

Bradykinin Modulation of Tumor Vasculature: II. Activation of Nitric Oxide and Phospholipase A2/Prostaglandin Signaling Pathways Synergistically Modifies Vascular Physiology and Morphology to Enhance Delivery of Chemotherapeutic Agents to Tumors

Emerich, D. F., Dean, R. L., Snodgrass, P., Lafreniere, D., Agostino, M., Wiens, T., Xiong, H., Hasler, B. P., Marsh, J. P., Pink, M. M., et al. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38780-4 · Cited by 42

Hypoxia-responsive drug–drug conjugated nanoparticles for breast cancer synergistic therapy

Zhang, R., Li, Y., Zhang, M., Tang, Q., & Zhang, X. (2016) · RSC Advances · doi:10.1039/c6ra01560c · Cited by 39

pH‐Responsive Wormlike Micelles with Sequential Metastasis Targeting Inhibit Lung Metastasis of Breast Cancer

He, X., Yu, H., Bao, X., Cao, H., Yin, Q., Zhang, Z., & Li, Y. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201500626 · Cited by 38

cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis

Makino, J., Cabral, H., Miura, Y., Matsumoto, Y., Wang, M., Kinoh, H., Mochida, Y., Nishiyama, N., & Kataoka, K. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.10.017 · Cited by 34

Enhanced tumor targetability of PEGylated mesoporous silica nanoparticles on in vivo optical imaging according to their size

Kim, H. L., Lee, S. B., Jeong, H. J., & Kim, D. W. (2014) · RSC Advances · doi:10.1039/c4ra03905j · Cited by 32

cRGD-Modified Benzimidazole-based pH-Responsive Nanoparticles for Enhanced Tumor Targeted Doxorubicin Delivery

Liu, J., Liu, Q., Yang, C., Sun, Y., Zhang, Y., Huang, P., Zhou, J., Liu, Q., Chu, L., Huang, F., et al. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b01501 · Cited by 24

Drug Shortages and the Burden of Access to Care: A Critical Issue Affecting Patients With Cancer

McKeever, A. E., Bloch, J. R., & Bratic, A. (2013) · Clinical journal of oncology nursing · doi:10.1188/13.cjon.490-495 · Cited by 23

Bimodal Imaging of Inflammation with SPECT/CT and MRI Using Iodine-125 Labeled VCAM-1 Targeting Microparticle Conjugates

Patel, N., Duffy, B. A., Badar, A., Lythgoe, M. F., & Årstad, E. (2015) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5b00380 · Cited by 23

Hypoxia-sensitive bis(2-(2′-benzothienyl)pyridinato-N,C3′)iridium[poly(n-butyl cyanoacrylate]/chitosan nanoparticles and their phosphorescence tumor imaging in vitro and in vivo

Zeng, Y., Zhang, S., Jia, M., Liu, Y., Shang, J., Guo, Y., Xu, J., & Wu, D. (2013) · Nanoscale · doi:10.1039/c3nr04349e · Cited by 20

Batimastat Nanoparticles Associated with Transcatheter Arterial Chemoembolization Decrease Hepatocellular Carcinoma Recurrence

Liang, X., & Wang, M. (2014) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-014-9893-8 · Cited by 9

Polymeric Nanoparticles for Drug Delivery

Beach, M. A., Nayanathara, U., Gao, Y., Zhang, C., Xiong, Y., Wang, Y., & Such, G. K. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00705 · Cited by 1,155

Biomedicine Meets Fenton Chemistry

Tang, Z., Zhao, P., Wang, H., Liu, Y., & Bu, W. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00977 · Cited by 745

Biodegradable Biomimic Copper/Manganese Silicate Nanospheres for Chemodynamic/Photodynamic Synergistic Therapy with Simultaneous Glutathione Depletion and Hypoxia Relief

Liu, C., Wang, D., Zhang, S., Cheng, Y., Yang, F., Xing, Y., Xu, T., Dong, H., & Zhang, X. (2019) · ACS Nano · doi:10.1021/acsnano.8b09387 · Cited by 641

Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy

Du, R., Huang, C., Liu, K., Li, X., & Dong, Z. (2021) · Molecular Cancer · doi:10.1186/s12943-020-01305-3 · Cited by 586

Dual‐Peak Absorbing Semiconducting Copolymer Nanoparticles for First and Second Near‐Infrared Window Photothermal Therapy: A Comparative Study

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