The other side of the superoxide radical anion: Its ability to chemically repair DNA oxidized sites
Abstract
Even though reaction of the superoxide anion radical/hydroperoxide radical could lead to oxidation of biomolecules, it can reduce oxidized DNA at diffusion controlled rates.
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This type of involvement of superoxide in chemical processes has not yet been studied in depth.
“Unfortunately, this type of involvement in chemical processes has not yet been studied in depth [169].”
From Superoxide Anion Chemistry—Its Role at the Core of the Innate Immunity (2023) · cites this paper as [169]
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Self-citation
- Authors
- Muñoz-Rugeles, L., Galano, A., & Alvarez-Idaboy, J. R.
- Affiliations
- Facultad de Química
- Universidad Autónoma Metropolitana (MX)
- Universidad Nacional Autónoma de México (MX)
- Corresponding author
- Alvarez-Idaboy, Juan Raúl
- Venue
- Chemical Communications
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2018
- Volume
- 54
- Issue
- 97
- Pages
- 13710-13713
- ISSN
- 1359-7345 (ISSN-L)
- 1364-548X
- OpenAlex
- W2901654777
- Cited by
- 18
- References
- 21
- Citations by year
- 2026: 3 · 2025: 2 · 2023: 5 · 2021: 3 · 2020: 2 · 2019: 3
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Communications (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México (UNAM PAPIIT IN223018, LANCAD-UNAM-DGTIC-192)
- Consejo Nacional de Ciencia y Tecnología (270309)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Free Radicals and Antioxidants
- Physical Sciences › Chemistry › Inorganic Chemistry › Metal-Catalyzed Oxygenation Mechanisms
- Physical Sciences › Chemistry › Organic Chemistry › Chemical Reaction Mechanisms
- Keywords
- superoxide, DNA repair, oxidative DNA damage, electron transfer, acid-base balance, pH dependence, reaction mechanism, DNA oxidation
- MeSH terms
- Anions, Binding Sites, DNA, DNA Damage, Electron Transport, Hydrogen-Ion Concentration, Oxidation-Reduction, Superoxides
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