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Cited by 2653D Printing in Biomedical ResearchMicrofluidic and Capillary Electrophoresis ApplicationsCancer Immunotherapy and Biomarkers

3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade

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Aref, Amir R., Campisi, Marco, Ivanova, Elena, Portell, Andrew, Larios, Dalia, Piel, Brandon P., Mathur, Natasha, Zhou, Chensheng +15 more·2018·Lab on a Chip
DOI 10.1039/c8lc00322jPMC PMC6274590
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Microfluidic culture has the potential to revolutionize cancer diagnosis and therapy.

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Cited by

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Authors
Aref, A. R., Campisi, M., Ivanova, E., Portell, A., Larios, D., Piel, B. P., Mathur, N., Zhou, C., Coakley, R. V., Bartels, A., Bowden, M., Herbert, Z., Hill, S., Gilhooley, S., Carter, J., Cañadas, I., Thai, T. C., Kitajima, S., Chiono, V., Paweletz, C. P., Barbie, D. A., Kamm, R. D., & Jenkins, R. W.
Affiliations
  • Dana-Farber Cancer Institute (US)
  • Politecnico di Torino (IT)
  • Department of Medical Oncology
  • Massachusetts Institute of Technology (US)
  • Harvard University (US)
Corresponding author
Jenkins, Russell W.
ORCID
Venue
Lab on a Chip
Publisher
Royal Society of Chemistry (RSC)
Published
2018
Volume
18
Issue
20
Pages
3129-3143
ISSN
  • 1473-0189 (ISSN-L)
  • 1473-0197
DOI
10.1039/c8lc00322j
PMC
PMC6274590
OpenAlex
W2892074270
Cited by
265
References
11
Citations by year
2026: 19 · 2025: 27 · 2024: 41 · 2023: 47 · 2022: 33 · 2021: 47 · 2020: 39 · 2019: 10 · 2018: 1 · 2017: 1
FWCI
9.69
Type
journal article
Language
en
Open access
Licence
Locations
  • Lab on a Chip (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • PORTO@Iris (submittedVersion, cc-by-nc)
  • DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by-nc)
  • The Royal Society of Chemistry
Funders
  • National Cancer Institute (CA190394-01, CA214381-01, T32CA009172-41)
  • Massachusetts Institute of Technology (BIOMODE)
  • Politecnico di Torino (BIOMODE)
  • Compagnia di San Paolo
  • American Cancer Society (SU2C-AACR-DT17-15)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
  • Physical Sciences › Engineering › Biomedical Engineering › Microfluidic and Capillary Electrophoresis Applications
  • Health Sciences › Medicine › Oncology › Cancer Immunotherapy and Biomarkers
Keywords
immune checkpoint blockade, tumor-immune interactions, tumor microenvironment, cancer immunotherapy response prediction, precision oncology
MeSH terms
Animals, Immunity, Spheroids, Cellular, Cell Culture Techniques, Cell Line, Tumor, Mice, Lab-On-A-Chip Devices

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