ACE-inhibitory and antioxidant peptides from coconut cake albumin hydrolysates: purification, identification and synthesis
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Three ACE-inhibitory and antioxidant peptides were identified from enzymatic hydrolysates of coconut cake albumin in the current study.
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The peptides KAQYPYV, KIIIYN, and KILIYG may have potential antihypertensive effects.
“Furthermore, the peptides reduced intracellular endothelin-1 content and protected vascular endothelial cells from ROS-mediated damage, suggesting potential antihypertensive effects.”
From Nutritional composition and bioactive properties of tropical coconut palm fruit with functional food applications (2025) · cites this paper as [104]
The peptides KAQYPYV, KIIIYN, and KILIYG exhibited ACE-inhibitory activity (IC50: 37.06-58.72 μM) and hydroxyl radical scavenging capacity (IC50: 70.84-95.23 μM).
“These peptides exhibited potent ACE-inhibitory activity (IC50: 37.06–58.72 µM) and hydroxyl radical scavenging capacity (IC50: 70.84–95.23 µM).”
From Nutritional composition and bioactive properties of tropical coconut palm fruit with functional food applications (2025) · cites this paper as [104]
Zheng et al. isolated three novel peptides from coconut cake albumin hydrolysates: KAQYPYV, KIIIYN, and KILIYG, with molecular masses of 867.45, 762.47, and 705.44 Da, respectively.
“Zheng et al. [104] isolated three novel peptides from CCA hydrolysates: KAQYPYV, KIIIYN, and KILIYG, with molecular masses of 867.45, 762.47, and 705.44 Da, respectively.”
From Nutritional composition and bioactive properties of tropical coconut palm fruit with functional food applications (2025) · cites this paper as [104]
The peptides KAQYPYV, KIIIYN, and KILIYG reduced intracellular endothelin-1 content and protected vascular endothelial cells from ROS-mediated damage.
“Furthermore, the peptides reduced intracellular endothelin-1 content and protected vascular endothelial cells from ROS-mediated damage, suggesting potential antihypertensive effects.”
From Nutritional composition and bioactive properties of tropical coconut palm fruit with functional food applications (2025) · cites this paper as [104]
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- Authors
- Zheng, Y., Li, Y., & Li, G.
- Affiliations
- Shanxi Normal University (CN)
- Corresponding author
- Zheng, Yajun
- Venue
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2019
- Volume
- 9
- Issue
- 11
- Pages
- 5925-5936
- ISSN
- 2046-2069 (ISSN-L)
- PMC
- PMC9060905
- OpenAlex
- W2913448350
- Cited by
- 37
- References
- 41
- Citations by year
- 2025: 6 · 2024: 4 · 2023: 2 · 2022: 12 · 2021: 3 · 2020: 8 · 2019: 2
- FWCI
- 2.07
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- RSC Advances (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Shanxi Normal University (2015YZKC-07)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Hydrolysis and Bioactive Peptides
- Physical Sciences › Chemistry › Inorganic Chemistry › Coconut Research and Applications
- Health Sciences › Medicine › Oncology › Peptidase Inhibition and Analysis
- Keywords
- ACE inhibitory peptides, antioxidant peptides, protein hydrolysates, bioactive peptides, peptide purification, peptide synthesis
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