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Photodynamic therapy and anti-tumour immunity

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Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

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A graphene quantum dot photodynamic therapy agent with high singlet oxygen generation

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Singlet oxygen: there is indeed something new under the sun

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Photo-, Thermo-, Solvato-, and Electrochromic Spiroheterocyclic Compounds

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H 2 O 2 -Activatable and O 2 -Evolving Nanoparticles for Highly Efficient and Selective Photodynamic Therapy against Hypoxic Tumor Cells

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Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells

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Metal‐Organic Framework Nanoparticles in Photodynamic Therapy: Current Status and Perspectives

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A Smart Photosensitizer–Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells

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Spiropyran-Based Photochromic Polymer Nanoparticles with Optically Switchable Luminescence

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Ultrasound-Induced Reactive Oxygen Species Mediated Therapy and Imaging Using a Fenton Reaction Activable Polymersome

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Photochromic Metal–Organic Frameworks: Reversible Control of Singlet Oxygen Generation

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Reversibly Photoswitchable Dual-Color Fluorescent Nanoparticles as New Tools for Live-Cell Imaging

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Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes

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Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer

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Reversibly Switching Bilayer Permeability and Release Modules of Photochromic Polymersomes Stabilized by Cooperative Noncovalent Interactions

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Metallophthalocyanine‐Based Conjugated Microporous Polymers as Highly Efficient Photosensitizers for Singlet Oxygen Generation

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Reversible Three‐State Switching of Multicolor Fluorescence Emission by Multiple Stimuli Modulated FRET Processes within Thermoresponsive Polymeric Micelles

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An upconversion nanoparticle – Zinc phthalocyanine based nanophotosensitizer for photodynamic therapy

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Optical lock-in detection imaging microscopy for contrast-enhanced imaging in living cells

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Remote‐Controlled Release of Singlet Oxygen by the Plasmonic Heating of Endoperoxide‐Modified Gold Nanorods: Towards a Paradigm Change in Photodynamic Therapy

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Synthesis of a Barbell-like Triblock Copolymer, Poly( l -lysine) Dendrimer- block -Poly(ethylene glycol)- block -Poly( l -lysine) Dendrimer, and Its Self-Assembly with Plasmid DNA

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Photoswitched Singlet Energy Transfer in a Porphyrin−Spiropyran Dyad

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Reversible Photochemical Control of Singlet Oxygen Generation Using Diarylethene Photochromic Switches

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Polymeric assemblies and nanoparticles with stimuli-responsive fluorescence emission characteristics

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Photochromic polyphosphazenes with spiropyran units

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pH‐Responsive Polymers as Gene Carriers

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The role of PEG architecture and molecular weight in the gene transfection performance of PEGylated poly(dimethylaminoethyl methacrylate) based cationic polymers

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Direct Aqueous Self-Assembly of an Amphiphilic Diblock Copolymer toward Multistimuli-Responsive Fluorescent Anisotropic Micelles

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Mechanistic Differences in DNA Nanoparticle Formation in the Presence of Oligolysines and Poly- l -lysine

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Synthesis of decacationic [60]fullerene decaiodides giving photoinduced production of superoxide radicals and effective PDT-mediation on antimicrobial photoinactivation

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A Ratiometric Fluorescent Sensor for Cd2+ Based on Internal Charge Transfer

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Controlled Generation of Singlet Oxygen in Living Cells with Tunable Ratios of the Photochromic Switch in Metal–Organic Frameworks

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From spontaneously formed aggregates to J-aggregates of photochromic spiropyran

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Picosecond time-resolved fluorescence spectroscopy of the photochromic reaction of spiropyran in Langmuir-Blodgett films

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Photochromic liquid crystalline cyclic siloxanes containing spiropyran groups

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Naturally occurring branched-chain polyamines induce a crosslinked meshwork structure in a giant DNA

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Photochemical tissue penetration via photosensitizer for effective drug penetration in a non-vascular tumor

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Nurses and Pharmacists in Interdisciplinary Team of Health Care Providers in Photodynamic Therapy

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Light: A Magical Tool for Controlled Drug Delivery

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Spiropyran-based advanced photoswitchable materials: A fascinating pathway to the future stimuli-responsive devices

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Activatable Type I Photosensitizer with Quenched Photosensitization Pre and Post Photodynamic Therapy

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Paper without a Trail: Time‐Dependent Encryption using Pillar[5]arene‐Based Host–Guest Invisible Ink

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Review on recent trends and prospects in π‐conjugated luminescent aggregates for biomedical applications

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Multi-Stimuli Responsive FRET Processes of Bifluorophoric AIEgens in an Amphiphilic Copolymer and Its Application to Cyanide Detection in Aqueous Media

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Fusion of aggregation-induced emission and photochromics for promising photoresponsive smart materials

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Photopharmacology and photoresponsive drug delivery

Liu, Y., Wang, T., & Wang, W. (2025) · Chemical Society Reviews · doi:10.1039/d5cs00125k · Cited by 100

Photoswitchable ultrahigh-brightness red fluorescent polymeric nanoparticles for information encryption, anti-counterfeiting and bioimaging

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Vacancy-enhanced generation of singlet oxygen for photodynamic therapy

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Photoactivatable Biomedical Materials Based on Luminogens with Aggregation‐Induced Emission (AIE) Characteristics

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Recent Advances in the Biomedical Applications of Functionalized Nanogels

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Light responsive nucleic acid for biomedical application

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A novel photoswitchable AIE-active supramolecular photosensitizer with synergistic enhancement of ROS-generation ability constructed by a two-step sequential FRET process

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Aggregation‐Induced Emission Luminogens with Photoresponsive Behaviors for Biomedical Applications

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Photo‐Modulating Multicolor Photoluminescence Including White‐Light Emission from a Photochromic Copolymer

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Temozolomide–Doxorubicin Conjugate as a Double Intercalating Agent and Delivery by Apoferritin for Glioblastoma Chemotherapy

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Prevent or Cure—The Unprecedented Need for Self‐Reporting Materials

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Supramolecular materials based on AIEgens for photo-assisted therapy

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Polymeric nano-carriers for on-demand delivery of genes via specific responses to stimuli

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Spiropyran-based photoswitchable acrylic nanofibers: A stimuli-responsive substrate for light controlled C6 glioma cells attachment/detachment

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Designs and Applications of Multi-stimuli Responsive FRET Processes in AIEgen-Functionalized and Bi-fluorophoric Supramolecular Materials

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Photo-controlled fluorescence “Double-Check” for human serum albumin and its applications

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Dual Functional Half‐Sandwich Ru(II) Complexes: Lysosome‐Targeting Probes and Anticancer Agents

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Stimuli-responsive nanoparticles based on poly acrylic derivatives for tumor therapy

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Phase‐Separated Spiropyran Coacervates as Dual‐Wavelength‐Switchable Reactive Oxygen Generators

Kong, H., Xie, X. N., Bao, Y., Zhang, F., Bian, L., Cheng, K., Zhao, Y., & Xia, J. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202419538 · Cited by 28

Photochromic materials as a photosensitizer in reversible reactive singlet oxygen generation

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Photocyclization of diarylethenes: the effect of imidazole on the oxidative photodegradation process

Zakharov, A. V., Lvov, A. G., Rostovtseva, I. A., Метелица, А. В., Chernyshev, A. V., Krayushkin, М. М., Yadykov, A. V., & Ширинян, В. З. (2019) · Photochemical & Photobiological Sciences · doi:10.1039/c8pp00507a · Cited by 23

Development of stimuli responsive polymeric nanomedicines modulating tumor microenvironment for improved cancer therapy

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Photoswitching the fluorescence of nanoparticles for advanced optical applications

Zhong, W., & Shang, L. (2024) · Chemical Science · doi:10.1039/d4sc00114a · Cited by 22

Construction of aggregation-induced emission photosensitizers through host-guest interactions for photooxidation reaction and light-harvesting

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Activatable Type I Photosensitizer with Quenched Photosensitization Pre and Post Photodynamic Therapy

Tian, J., Li, B., Zhang, F., Yao, Z., Song, W., Tang, Y., Yuan, P., & Liu, B. (2023) · Angewandte Chemie · doi:10.1002/ange.202307288 · Cited by 20

Application of stimuli-responsive FRET behavior toward cyanide detection in a photo-switchable [2]pseudorotaxane polymer containing the BODIPY donor and the merocyanine acceptor

Gouda, C., Barik, D., Maitra, C., Liang, K.-C., Ho, F.-C., Srinivasadesikan, V., Chandran, S., Wu, S., Lin, M. C., & Lin, H. (2020) · Journal of Materials Chemistry C · doi:10.1039/d0tc05000h · Cited by 20

Light-Controlled in Vitro Gene Delivery Using Polymer-Tethered Spiropyran as a Photoswitchable Photosensitizer

Ji, J., Wu, T., Zhang, Y., & Feng, F. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b22505 · Cited by 19

A spiropyran with low pKa for tracking DNA G-quadruplexes and revealing the dissipation of ΔΨm with senescence using an in-situ switching strategy

Tian, X., Li, J., Zhang, Y., Gao, Y. J., Afzal, M. W., Wang, A., James, T. D., Bai, Y., & Guo, Y. (2022) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2022.131618 · Cited by 18

SET-LRP from Programmed Difunctional Initiators Encoded with Double Single-Cleavage and Double Dual-Cleavage Groups

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Synthesis of a Negative Photochrome with High Switching Quantum Yields and Capable of Singlet‐Oxygen Production and Storage

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Optical properties of phosphonium-, quaternary ammonium- and imidazolium- substituted regioregular polythiophenes and application for imaging live cells

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Hyaluronan-fullerene/AIEgen nanogel as CD44-targeted delivery of tirapazamine for synergistic photodynamic-hypoxia activated therapy

Hong, X., Xu, X., Liu, Z., Liu, S., Yu, J., Wu, M., Ma, Y., & Shuai, Q. (2021) · Nanotechnology · doi:10.1088/1361-6528/ac18da · Cited by 14

Emerging frontiers in spiropyran-driven photoresponsive drug delivery systems and technologies

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Merocyanine Complexes Coupled with Plasmonic Au Nanoparticles for Inhibiting Tau Aggregation

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Preparation of reversible photoresponsive N-hydroxyethyl spiropyran/polyacrylonitrile fiber materials with mechanical stability by electrospinning for regulating wettability and humidity automatically

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Preparation of Photoswitchable Polyacrylic Nanocomposite Fibers Containing Au Nanorods and Spiropyran: Optical and Plasmonic Properties

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Light and temperature dual stimuli-responsive micelles from carbamate-containing spiropyran-based amphiphilic block copolymers: Fabrication, responsiveness and controlled release behaviors

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Photoswitchable Cytotoxins

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IgG-Binding Peptidomimetic Mixed-Charge Polymer-Modified Resins for Chromatographic Purification of Antibodies

Deura, K., Sakama, A., Moriwaki, Y., Citterio, D., & Hiruta, Y. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c16861 · Cited by 7

Intracellularly Self-Assembled 2D Materials Induce Apoptotic Cell Death by Impeding Cytosolic Transport

Hou, D., Xu, Y. X., Yan, J., Zeng, Q., Wang, Z. J., & Chen, Y. (2023) · ACS Nano · doi:10.1021/acsnano.2c11876 · Cited by 6

Construction and synergistic anti-tumor study of a tumor microenvironment-based multifunctional nano-drug delivery system

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Well-controlled spiropyran functionalized polystyrenes via a combination of anionic polymerization and hydrosilylation for photoinduced solvatochromism

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Oxidative burst as a continuous H 2 O 2 supplier for tumor oxygenation in photodynamic therapy

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Facile Synthesis of a Carnosine‐Pendent Cationic Polymer via Free Radical Polymerization and Application in Gene Delivery

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