Recent progress in non-native nucleic acid modifications

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Generation and Enzymatic Amplification of High‐Density Functionalized DNA Double Strands

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Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins

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Evolution of a General RNA-Cleaving FANA Enzyme

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Highly stable hexitol based XNA aptamers targeting the vascular endothelial growth factor

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Novel Combinatorial Selection of Phosphorothioate Oligonucleotide Aptamers

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Allosteric Regulation of DNAzyme Activities through Intrastrand Transformation Induced by Cu(II)-Mediated Artificial Base Pairing

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Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing

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Guide RNA modification as a way to improve CRISPR/Cas9-based genome-editing systems

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Control of the Chirality and Helicity of Oligomers of Serinol Nucleic Acid (SNA) by Sequence Design

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G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold

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Mechanochemistry of nucleosides, nucleotides and related materials

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Chemical Synthesis and Biological Application of Modified Oligonucleotides

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Identification and characterization of nucleobase-modified aptamers by click-SELEX

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siRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2

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RNA Cloaking by Reversible Acylation

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Structural basis for the targeting of complement anaphylatoxin C5a using a mixed L-RNA/L-DNA aptamer

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One‐Flow, Multistep Synthesis of Nucleosides by Brønsted Acid‐Catalyzed Glycosylation

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Nucleic Acids with a Six‐Membered ‘Carbohydrate’ Mimic in the Backbone

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Crystal Structure of Double Helical Hexitol Nucleic Acids

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Structural Requirements at the Catalytic Site of the Heteroduplex Substrate for Human RNase H1 Catalysis

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In Vitro Selection of Diversely Functionalized Aptamers

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A Dual-App Nucleoside Probe Provides Structural Insights into the Human Telomeric Overhang in Live Cells

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DNA-Catalyzed Amide Hydrolysis

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Modulation of thermal stability can enhance the potency of siRNA

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Synthesis, Improved Antisense Activity and Structural Rationale for the Divergent RNA Affinities of 3′-Fluoro Hexitol Nucleic Acid (FHNA and Ara-FHNA) Modified Oligonucleotides

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