Recent progress in non-native nucleic acid modifications

Chemical Profiling of A‐to‐I RNA Editing Using a Click‐Compatible Phenylacrylamide

Knutson, S. D., Korn, M. M., Johnson, R. P., Monteleone, L. R., Dailey, D. M., Swenson, C., Beal, P. A., & Heemstra, J. M. (2020) · Chemistry - A European Journal · doi:10.1002/chem.202001667 · Cited by 17

DNA Photocleavage by DNA and DNA−LNA Amino Acid−Dye Conjugates

Biton, A., Ezra, A., Kašpárková, J., Brabec, V., & Yavin, E. (2010) · Bioconjugate Chemistry · doi:10.1021/bc900372h · Cited by 16

A one-pot synthesis of α-l-threofuranosyl nucleoside triphosphates (tNTPs)

Sau, S. P., & Chaput, J. C. (2016) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2016.05.057 · Cited by 16

Base‐Pairing Properties of Double‐Headed Nucleotides

Hornum, M., Stendevad, J., Sharma, P. K., Kumar, P., Nielsen, R. B., Petersen, M. Å., & Nielsen, P. (2019) · Chemistry - A European Journal · doi:10.1002/chem.201901077 · Cited by 16

On the Enzymatic Formation of Metal Base Pairs with Thiolated and p K a ‐Perturbed Nucleotides

Lévi-Acobas, F., Röthlisberger, P., Sarac, I., Marlière, P., Herdewijn, P. A., & Hollenstein, M. (2019) · ChemBioChem · doi:10.1002/cbic.201900399 · Cited by 16

Compatibility of 5-ethynyl-2′F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers

Lévi-Acobas, F., Katolik, A., Röthlisberger, P., Cokelaer, T., Sarac, I., Damha, M. J., Leumann, C. J., & Hollenstein, M. (2019) · Organic & Biomolecular Chemistry · doi:10.1039/c9ob01515a · Cited by 16

Evaluating the Catalytic Potential of a General RNA‐Cleaving FANA Enzyme

Wang, Y., Vorperian, A., Shehabat, M., & Chaput, J. C. (2019) · ChemBioChem · doi:10.1002/cbic.201900596 · Cited by 16

Discovery of an Unnatural DNA Modification Derived from a Natural Secondary Metabolite

Wang, T., & Kohli, R. M. (2020) · Cell chemical biology · doi:10.1016/j.chembiol.2020.09.006 · Cited by 16

Structure‐Guided Tuning of a Selectivity Switch towards Ribonucleosides in Trypanosoma brucei Purine Nucleoside 2′‐Deoxyribosyltransferase

Arco, J. D., Mills, A., Gago, F., & Fernández‐Lucas, J. (2019) · ChemBioChem · doi:10.1002/cbic.201900397 · Cited by 15

Bacterial Cell Display as a Robust and Versatile Platform for Engineering Low‐Affinity Ligands and Enzymes

Csibra, E., Renders, M., & Pinheiro, V. B. (2020) · ChemBioChem · doi:10.1002/cbic.202000203 · Cited by 15

Universal hybridization using LNA (locked nucleic acid) containing a novel pyrene LNA nucleotide monomer.

Babu, B. R., & Wengel, J. (2001) · Chemical Communications · doi:10.1039/b106065c · Cited by 14

Facile access to modified and functionalized PNAs through Ugi-based solid phase oligomerization

Saarbach, J., Masi, D., Zambaldo, C., & Winssinger, N. (2017) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2017.05.064 · Cited by 14

Towards Improved Oligonucleotide Therapeutics Through Faster Target Binding Kinetics

Menzi, M., Wild, B., Pradère, U., Malinowska, A. L., Brunschweiger, A., Lightfoot, H. L., & Hall, J. (2017) · Chemistry - A European Journal · doi:10.1002/chem.201701670 · Cited by 14

Sequencing Mirror-Image DNA Chemically

Liu, X., & Zhu, T. F. (2018) · Cell Chemical Biology · doi:10.1016/j.chembiol.2018.06.005 · Cited by 14

Synthesis and Biochemical Characterization of Tricyclothymidine Triphosphate (tc‐TTP)

Hollenstein, M., & Leumann, C. J. (2014) · ChemBioChem · doi:10.1002/cbic.201402116 · Cited by 13

Seven-Membered Ring Nucleoside Analogues: Stereoselective Synthesis and Studies on Their Conformational Properties

Habibian, M., Martínez‐Montero, S., Portella, G., Chua, Z., Bohle, D. S., Orozco, M., & Damha, M. J. (2015) · Organic Letters · doi:10.1021/acs.orglett.5b02769 · Cited by 13

Condensing the information in DNA with double-headed nucleotides

Hornum, M., Sharma, P. K., Reslow-Jacobsen, C., Kumar, P., Petersen, M. Å., & Nielsen, P. (2017) · Chemical Communications · doi:10.1039/c7cc05047j · Cited by 13

Double-headed nucleotides as xeno nucleic acids: information storage and polymerase recognition

Beck, K. M., Krogh, M. B., Hornum, M., Ludford, P. T., Tor, Y., & Nielsen, P. (2020) · Organic & Biomolecular Chemistry · doi:10.1039/d0ob01426e · Cited by 13

Photoactivatable oligonucleotide probes to trap single-stranded DNA binding proteins: Updating the potential of 4-thiothymidine from a comparative study

Gérard-Hirne, T., Thiebaut, F., Sachon, E., Désert, A., Drujon, T., Guérineau, V., Michel, B. Y., Benhida, R., Coulon, S., Saintomé, C., et al. (2018) · Biochimie · doi:10.1016/j.biochi.2018.08.007 · Cited by 12

The crystal structure of a natural DNA polymerase complexed with mirror DNA

An, J., Choi, J., Hwang, D., Park, J., Pemble, C. W., IV, Duong, T. H. M., Kim, K., Ahn, H., Chung, H. S., & Ahn, D. (2020) · Chemical Communications · doi:10.1039/c9cc09351f · Cited by 12

Enzymatic Construction of Artificial Base Pairs: The Effect of Metal Shielding

Flamme, M., Lévi-Acobas, F., Hensel, S., Naskar, S., Röthlisberger, P., Sarac, I., Gasser, G., Müller, J., & Hollenstein, M. (2020) · ChemBioChem · doi:10.1002/cbic.202000402 · Cited by 12

Synthesis of Novel -substituted guanidine linked nucleoside dimers and their incorporation into oligonucleotides

Vandendriessche, F., Voortmans, M., Hoogmartens, J., Aerschot, A. A. V., & Herdewijn, P. A. (1993) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/s0960-894x(01)80875-1 · Cited by 11

Dendrimer‐Based Signal Amplification of Click‐Labelled DNA in Situ

Raddaoui, N., Stazzoni, S., Möckl, L., Viverge, B., Geiger, F., Engelke, H., Bräuchle, C., & Carell, T. (2017) · ChemBioChem · doi:10.1002/cbic.201700209 · Cited by 11

Spotting, Transcription and In Situ Synthesis: Three Routes for the Fabrication of RNA Microarrays

Lietard, J., & Somoza, M. M. (2019) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2019.06.004 · Cited by 11

Incorporation of a minimal nucleotide into DNA

Röthlisberger, P., Lévi-Acobas, F., Sarac, I., Ricoux, R., Mahy, J., Herdewijn, P. A., Marlière, P., & Hollenstein, M. (2018) · Tetrahedron Letters · doi:10.1016/j.tetlet.2018.10.036 · Cited by 10

Kinetic analysis of N -alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases

Renders, M., Dumbre, S. G., Abramov, M., Kestemont, D., Margamuljana, L., Largy, E., Cozens, C., Vandenameele, J., Pinheiro, V. B., Toye, D., et al. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz008 · Cited by 10

Synthesis of an acp 3 U phosphoramidite and incorporation of the hypermodified base into RNA

Nainytė, M., Amatov, T., & Carell, T. (2019) · Chemical Communications · doi:10.1039/c9cc06314e · Cited by 10

Nucleobase-Functionalized 5-Aza-7-deazaguanine Ribo- and 2′-Deoxyribonucleosides: Glycosylation, Pd-Assisted Cross-Coupling, and Photophysical Properties

Leonard, P., Kondhare, D., Jentgens, X., Daniliuc, C. G., & Seela, F. (2019) · The Journal of Organic Chemistry · doi:10.1021/acs.joc.9b01347 · Cited by 10

PCR incorporation of dUMPs modified with aromatic hydrocarbon substituents of different hydrophilicities: Synthesis of C5-modified dUTPs and PCR studies using Taq, Tth, Vent (exo-) and Deep Vent (exo-) polymerases

Zasedateleva, O. A., Суржиков, С. А., Shershov, V. E., Miftakhov, R. A., Yurasov, D. A., Kuznetsova, V. E., & Chudinov, A. V. (2020) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2020.103829 · Cited by 10

In What Ways Do Synthetic Nucleotides and Natural Base Lesions Alter the Structural Stability of G-Quadruplex Nucleic Acids?

Sági, J. (2017) · Journal of Nucleic Acids · doi:10.1155/2017/1641845 · Cited by 9

Versatile 3′ Functionalization of CRISPR Single Guide RNA

Palumbo, C. M., Gutierrez‐Bujari, J. M., O’Geen, H., Segal, D. J., & Beal, P. A. (2020) · ChemBioChem · doi:10.1002/cbic.201900736 · Cited by 9

Synthesis of cationic glucosamino nucleic acids for stabilizing oligonucleotides

Kitamura, Y., Moribe, S., & Kitade, Y. (2018) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2018.08.024 · Cited by 8

Synthesis of Chimeric Oligonucleotides Having Modified Internucleotide Linkages via an Automated H‐Phosphonate/Phosphoramidite Approach

Vlaho, D., & Damha, M. J. (2018) · Current Protocols in Nucleic Acid Chemistry · doi:10.1002/cpnc.53 · Cited by 7

A Single Amino Acid Substitution in Therminator DNA Polymerase Increases Incorporation Efficiency of Deoxyxylonucleotides

Bauwens, B., Rozenski, J., Herdewijn, P. A., & Robben, J. (2018) · ChemBioChem · doi:10.1002/cbic.201800411 · Cited by 6

transcription factor SATB1 CUTr1 domain in complex with a phosphorothioate DNA

Akutsu, Y., Kubota, T., Yamasaki, T., & Yamasaki, K. (2019) · Worldwide Protein Data Bank · doi:10.2210/pdb6lff/pdb · Cited by 6

New Metal‐Free Route towards Imidazole‐Substituted Uridine

Mattelaer, H., Hool, A. V., de Jong, F., der Auweraer, M. V., Meervelt, L. V., Dehaen, W., & Herdewijn, P. A. (2020) · European Journal of Organic Chemistry · doi:10.1002/ejoc.202000563 · Cited by 6

Synthesis of selenomethylene-locked nucleic acids (SeLNA) nucleoside unit bearing an adenine base

Moai, Y., Hiroaki, H., Obika, S., & Kodama, T. (2019) · Nucleosides Nucleotides & Nucleic Acids · doi:10.1080/15257770.2019.1675169 · Cited by 3

Drug delivery systems for RNA therapeutics

Paunovska, K., Loughrey, D., & Dahlman, J. E. (2022) · Nature Reviews Genetics · doi:10.1038/s41576-021-00439-4 · Cited by 1,349

Therapeutic reversal of Huntington’s disease by in vivo self-assembled siRNAs

Zhang, L., Wu, T., Shan, Y., Li, G., Ni, X., Chen, X., Hu, X., Lin, L., Li, Y., Guan, Y., et al. (2021) · Brain · doi:10.1093/brain/awab354 · Cited by 97