A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems

Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art

Müller, R. (2000) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(00)00087-4 · Cited by 3,836

Solid lipid nanoparticles Production, characterization and applications

Mehnert, W. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00105-3 · Cited by 3,158

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations

Müller, R. H., Radtke, M., & Wissing, S. A. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(02)00118-7 · Cited by 2,116

Nanoparticle uptake: The phagocyte problem

Gustafson, H. H., Holt‐Casper, D., Grainger, D. W., & Ghandehari, H. (2015) · Nano Today · doi:10.1016/j.nantod.2015.06.006 · Cited by 1,458

Nanotech approaches to drug delivery and imaging

Sahoo, S. K., & Labhasetwar, V. D. (2003) · Drug Discovery Today · doi:10.1016/s1359-6446(03)02903-9 · Cited by 1,224

Solid lipid nanoparticles: A modern formulation approach in drug delivery system

Mukherjee, S., Ray, S., & Thakur, R. S. (2009) · Indian Journal of Pharmaceutical Sciences · doi:10.4103/0250-474x.57282 · Cited by 1,001

Solid lipid nanoparticles (SLN) for controlled drug delivery – Drug release and release mechanism

Mühlen, A. Z., Schwarz, C., & Mehnert, W. (1998) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(97)00150-1 · Cited by 945

Theranostic Nanomedicine

Lammers, T., Aime, S., Hennink, W. E., Storm, G., & Kiessling, F. M. (2011) · Accounts of Chemical Research · doi:10.1021/ar200019c · Cited by 906

Effect of light and temperature on zeta potential and physical stability in solid lipid nanoparticle (SLN™) dispersions

Freitas, C., & Müller, R. H. (1998) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(98)00092-1 · Cited by 690

Enhancement of gastrointestinal absorption of quercetin by solid lipid nanoparticles

Li, H., Zhao, X. B., Ma, Y., Zhai, G., Li, L., & Lou, H. (2008) · Journal of Controlled Release · doi:10.1016/j.jconrel.2008.10.002 · Cited by 666

Lipid nanoparticles for improved topical application of drugs for skin diseases☆

SCHAFERKORTING, M., MEHNERT, W., & KORTING, H. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.04.006 · Cited by 614

An emerging focus on lipids in extracellular vesicles

Skotland, T., Sagini, K., Sandvig, K., & Llorente, A. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.03.002 · Cited by 585

Solid lipid nanoparticles (SLN) for controlled drug delivery. I. Production, characterization and sterilization

Schwarz, C., Mehnert, W., Lucks, J. S., & Müller, R. H. (1994) · Journal of Controlled Release · doi:10.1016/0168-3659(94)90047-7 · Cited by 574

Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties

Jenning, V., Schäfer‐Korting, M., & Gohla, S. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00223-0 · Cited by 548

Vitamin A loaded solid lipid nanoparticles for topical use: occlusive properties and drug targeting to the upper skin

Jenning, V., Gysler, A., Schäfer‐Korting, M., & Gohla, S. (2000) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(99)00075-2 · Cited by 529

Correlation between long-term stability of solid lipid nanoparticles (SLN™) and crystallinity of the lipid phase

Freitas, C., & Müller, R. H. (1999) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(98)00074-5 · Cited by 484

Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain

Yang, S. C., Lu, L. F., Cai, Y., Zhu, J. B., Liang, B. W., & Yang, C. Z. (1999) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00007-3 · Cited by 475

Solvent injection as a new approach for manufacturing lipid nanoparticles – evaluation of the method and process parameters

Schubert, M. (2003) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(02)00130-3 · Cited by 455

Preparation of solid lipid nanoparticles by a solvent emulsification–diffusion technique

Trotta, M., Debernardi, F., & Caputo, O. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(03)00135-2 · Cited by 439

Lipid nanoparticles for parenteral delivery of actives

Joshi, M. D., & Müller, R. H. (2008) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2008.09.003 · Cited by 435

Crystallization tendency and polymorphic transitions in triglyceride nanoparticles

Bunjes, H., Westesen, K., & Koch, M. H. J. (1996) · International Journal of Pharmaceutics · doi:10.1016/0378-5173(95)04286-5 · Cited by 426

Physicochemical characterization of colloidal drug delivery systems such as reverse micelles, vesicles, liquid crystals and nanoparticles for topical administration

Müller-Goymann, C. C. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2004.03.028 · Cited by 404

Nanotheranostics and image-guided drug delivery: current concepts and future directions

Lammers, T., Kiessling, F., Hennink, W. E., & Storm, G. (2010) · Molecular Pharmaceutics · doi:10.1021/mp100228v · Cited by 397

Solid lipid nanoparticles for enhancing vinpocetine's oral bioavailability

Luo, Y., Chen, D., Ren, L., Zhao, X., & Qin, J. (2006) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.05.010 · Cited by 395

Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin

Cavalli, R., Gasco, M. R., Chetoni, P., Burgalassi, S., & Saettone, M. F. (2002) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(02)00080-7 · Cited by 389

Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery

Liu, J., Hu, W. S., Chen, H., Ni, Q., Xu, H., & Yang, X. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.08.007 · Cited by 384

Pharmacokinetics, tissue distribution and bioavailability of clozapine solid lipid nanoparticles after intravenous and intraduodenal administration

Manjunath, K., & Venkateswarlu, V. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.06.006 · Cited by 381

Cosmetic applications for solid lipid nanoparticles (SLN)

Wissing, S. A. (2003) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(02)00684-1 · Cited by 366

Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin

Kakkar, V., Singh, S., Singla, D., & Kaur, I. P. (2010) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201000310 · Cited by 352

Polyhydroxy surfactants for the formulation of lipid nanoparticles (SLN and NLC): Effects on size, physical stability and particle matrix structure

Kovačević, A. B., Savic, S. D., Vuleta, G. M., Müller, R. H., & Keck, C. M. (2011) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2010.12.036 · Cited by 342

Improvement of drug safety by the use of lipid-based nanocarriers

Lim, S. B., Banerjee, A., & Önyüksel, H. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.06.002 · Cited by 325

Body Distribution of Camptothecin Solid Lipid Nanoparticles After Oral Administration

Yang, S., Zhu, J., Yu, L., Liang, B., & Yang, C. (1999) · Pharmaceutical Research · doi:10.1023/a:1018888927852 · Cited by 324

Non-stealth and stealth solid lipid nanoparticles (SLN) carrying doxorubicin: pharmacokinetics and tissue distribution after i.v. administration to rats

Fundaro', A., Cavalli, R., Bargoni, A., Vighetto, D., Zara, G. P., & Gasco, M. R. (2000) · Pharmacological Research · doi:10.1006/phrs.2000.0695 · Cited by 317

Oral bioavailability of cyclosporine: Solid lipid nanoparticles (SLN®) versus drug nanocrystals

Müller, R. H., Runge, S., Ravelli, V., Mehnert, W., Thünemann, A. F., & Souto, E. B. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.02.045 · Cited by 304

Preparation and characterization of solid lipid nanoparticles loaded with doxorubicin

Subedi, R. K., Kang, K. W., & Choi, H. (2009) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2009.04.008 · Cited by 302

Effect of lipid core material on characteristics of solid lipid nanoparticles designed for oral lymphatic delivery

Paliwal, R., Paliwal, S. R., Vaidya, B., Khatri, K., Goyal, A. K., Mishra, N., Mehta, A., & Vyas, S. P. (2008) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2008.08.003 · Cited by 288

Preparation and characterization of ketoprofen-loaded solid lipid nanoparticles made from beeswax and carnauba wax

Kheradmandnia, S., Vasheghani‐Farahani, E., Nosrati, M., & Atyabi, F. (2010) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2010.06.003 · Cited by 278

Oral solid lipid nanoparticle-based antitubercular chemotherapy

Pandey, R., Sharma, S., & Khuller, G. K. (2005) · Tuberculosis · doi:10.1016/j.tube.2005.08.009 · Cited by 271

Lopinavir loaded solid lipid nanoparticles (SLN) for intestinal lymphatic targeting

Alex, M. R. A., Chacko, A. J., Jose, S., & Souto, E. B. (2010) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2010.10.002 · Cited by 267

Brain uptake of thiamine-coated nanoparticles

Lockman, P. R., Oyewumi, M. O., Koziara, J. M., Roder, K. E., Mumper, R. J., & Allen, D. D. (2003) · Journal of Controlled Release · doi:10.1016/j.jconrel.2003.08.006 · Cited by 260

Quantum dot-based theranostics

Ho, Y., & Leong, K. W. (2009) · Nanoscale · doi:10.1039/b9nr00178f · Cited by 258

Solid Lipid Nanoparticles: A Review

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Diazepam-Loaded Solid Lipid Nanoparticles: Design and Characterization

Abdelbary, G. A., & Fahmy, R. H. (2009) · AAPS PharmSciTech · doi:10.1208/s12249-009-9197-2 · Cited by 249

Preparation of solid lipid nanoparticles using a membrane contactor

Charcosset, C., El-Harati, A. A., & Fessi, H. (2005) · Journal of Controlled Release · doi:10.1016/j.jconrel.2005.07.023 · Cited by 249

The influence of solid lipid nanoparticles on skin hydration and viscoelasticity – in vivo study

Wissing, S. A., & Müller, R. H. (2003) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(03)00040-7 · Cited by 245

Solid lipid nanoparticles (SLN) for controlled drug delivery II. drug incorporation and physicochemical characterization

Schwarz, C. (1999) · Journal of Microencapsulation · doi:10.1080/026520499289185 · Cited by 235

Freeze-drying of drug-free and drug-loaded solid lipid nanoparticles (SLN)

Schwarz, C., & Mehnert, W. (1997) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(97)00222-6 · Cited by 234

Pulmonary toxicity of carbon nanotubes: a systematic report

Kayat, J., Gajbhiye, V., Tekade, R. K., & Jain, N. K. (2010) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2010.06.008 · Cited by 225

Polymorphism of Lipids

Luzzati, V., Tardieu, A., & Gulik‐Krzywicki, T. (1968) · Nature · doi:10.1038/2171028a0 · Cited by 215

Albumin microspheres for study of the reticuloendothelial system.

Scheffel, U., Rhodes, B. A., Natarajan, T. K., & Wagner, H. N. (1972) · PubMed · Cited by 207

Stability of lipid excipients in solid lipid nanoparticles☆

Radomska-Soukharev, A. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.04.004 · Cited by 206

Pharmacokinetic evaluation of oral fenofibrate nanosuspensions and SLN in comparison to conventional suspensions of micronized drug☆

Hanafy, A., Spahn-Langguth, H., Vergnault, G., Grenier, P., Tubić-Grozdanis, M., Lenhardt, T., & Langguth, P. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.04.005 · Cited by 203

Alzheimer's disease drug development and the problem of the blood‐brain barrier

Pardridge, W. M. (2009) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2009.06.003 · Cited by 203

Investigations on the occlusive properties of solid lipid nanoparticles (SLN).

Wissing, S. A., Lippacher, A., & Müller, R. (2001) · PubMed · Cited by 199

Cyclosporine-loaded solid lipid nanoparticles (SLN®): Drug–lipid physicochemical interactions and characterization of drug incorporation

Müller, R. H. (2007) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2007.07.006 · Cited by 199

Structural investigations on nanoemulsions, solid lipid nanoparticles and nanostructured lipid carriers by cryo-field emission scanning electron microscopy and Raman spectroscopy

Saupe, A., Gordon, K. C., & Rades, T. (2006) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2006.01.022 · Cited by 198

Drug Delivery Nanoparticles in Skin Cancers

Dianzani, C., Zara, G. P., Maina, G., Pettazzoni, P., Pizzimenti, S., Rossi, F., Gigliotti, C. L., Ciamporcero, E. S., Daga, M., & Barrera, G. (2014) · BioMed Research International · doi:10.1155/2014/895986 · Cited by 187

Exploring dendrimer towards dual drug delivery: pH responsive simultaneous drug-release kinetics

Tekade, R. K., Dutta, T., Gajbhiye, V., & Jain, N. K. (2008) · Journal of Microencapsulation · doi:10.1080/02652040802312572 · Cited by 182

Cationic solid-lipid nanoparticles can efficiently bind and transfect plasmid DNA

Olbrich, C., Bakowsky, U., Lehr, C., Müller, R. H., & Kneuer, C. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(01)00506-5 · Cited by 181

Cellular uptake and cytotoxicity of solid lipid nanospheres (SLN) incorporating doxorubicin or paclitaxel

Miglietta, A., Cavalli, R., Bocca, C., Gabriel, L., & Gasco, M. R. (2000) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(00)00562-7 · Cited by 180

Characterization of indomethacin-loaded lipid nanoparticles by differential scanning calorimetry

Castelli, F., Puglia, C., Sarpietro, M. G., Rizza, L., & Bonina, F. P. (2005) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2005.08.011 · Cited by 178

Studies on oral absorption of stearic acid SLN by a novel fluorometric method

Yuan, H., Chen, J., Du, Y., Hu, F., Zeng, S., & Zhao, H.-L. (2007) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2007.03.002 · Cited by 176

Development of Idarubicin and Doxorubicin Solid Lipid Nanoparticles to Overcome Pgp-Mediated Multiple Drug Resistance in Leukemia

Ma, P., Dong, X., Swadley, C. L., Gupte, A., Leggas, M. L., Ledebur, H. C., & Mumper, R. J. (2009) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2009.1021 · Cited by 174

Novel Multifunctional Theranostic Liposome Drug Delivery System: Construction, Characterization, and Multimodality MR, Near-Infrared Fluorescent, and Nuclear Imaging

Li, S., Goins, B., Zhang, L., & Bao, A. (2012) · Bioconjugate Chemistry · doi:10.1021/bc300175d · Cited by 172

Electrosprayed nanoparticles for drug delivery and pharmaceutical applications

Sridhar, R., & Ramakrishna, S. (2013) · Biomatter · doi:10.4161/biom.24281 · Cited by 171

Pharmacokinetics, tissue distribution and relative bioavailability of puerarin solid lipid nanoparticles following oral administration

Luo, C.-F., Yuan, M., Chen, M., Liu, S., Liu, Z., Huang, B., Liu, X.-W., & Xiong, W. (2011) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2011.02.064 · Cited by 158

Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity

Fangueiro, J. F., Andreani, T., Egea, M. A., García, M. L., Souto, S. B., Silva, A. M., & Souto, E. B. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.11.025 · Cited by 152

Effect of cationic lipid and matrix lipid composition on solid lipid nanoparticle-mediated gene transfer

Tabatt, K., Sameti, M., Olbrich, C., Müller, R. H., & Lehr, C. (2004) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2003.10.015 · Cited by 152

High melting lipid based approach for drug delivery: Solid lipid nanoparticles

Kumar, S., & Randhawa, J. K. (2013) · Materials Science and Engineering C · doi:10.1016/j.msec.2013.01.037 · Cited by 152

Lipid- and Polymer-Based Nanostructures for Cancer Theranostics

Luk, B. T., Fang, R. H., & Zhang, L. (2012) · Theranostics · doi:10.7150/thno.4381 · Cited by 147

Preparation, characterization, and in vitro and in vivo evaluation of lovastatin solid lipid nanoparticles

Suresh, G., Manjunath, K., Venkateswarlu, V., & Satyanarayana, V. (2007) · AAPS PharmSciTech · doi:10.1208/pt0801024 · Cited by 144

Pharmacokinetics and Tissue Distribution of Idarubicin-Loaded Solid Lipid Nanoparticles After Duodenal Administration to Rats

Zara, G. P., Bargoni, A., Cavalli, R., Fundaro', A., Vighetto, D., & Gasco, M. R. (2002) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10129 · Cited by 143

Topical Amphotericin B solid lipid nanoparticles: Design and development

Butani, D., Yewale, C. R., & Misra, A. R. (2015) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2015.07.032 · Cited by 143

Rifabutin-loaded solid lipid nanoparticles for inhaled antitubercular therapy: Physicochemical and in vitro studies

Gaspar, D. P., Faria, V., Gonçalves, L., Taboada, P., Remuñán‐López, C., & Almeida, A. J. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.11.050 · Cited by 136

Polymeric theranostics: using polymer-based systems for simultaneous imaging and therapy

Krasia‐Christoforou, T., & Georgiou, T. K. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb20191k · Cited by 135

Duodenal administration of solid lipid nanoparticles loaded with different percentages of tobramycin

Cavalli, R., Bargoni, A., Podio, V., Muntoni, E., Zara, G. P., & Gasco, M. R. (2003) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.10368 · Cited by 133

Effect of poloxamer 188 on lymphatic uptake of carvedilol-loaded solid lipid nanoparticles for bioavailability enhancement

Baboota, S., Shah, F. M., Javed, A., & Alka, A. (2009) · Journal of drug targeting · doi:10.1080/10611860902718672 · Cited by 128

Dendrimer Nanoscaffolds for Potential Theranostics of Prostate Cancer with a Focus on Radiochemistry

Lo, S., Kumar, A., Hsieh, J., & Sun, X. (2013) · Molecular Pharmaceutics · doi:10.1021/mp3005325 · Cited by 126

Monitoring pH-Triggered Drug Release from Radioluminescent Nanocapsules with X-ray Excited Optical Luminescence

Chen, H., Moore, T. L., Qi, B., Colvin, D. C., Jelen, E., Hitchcock, D. A., He, J. P., Mefford, O. T., Gore, J. C., Alexis, F., et al. (2013) · ACS Nano · doi:10.1021/nn304369m · Cited by 126

Solid lipid nanoparticles as carriers of hydrocortisone and progesterone complexes with β-cyclodextrins

Cavalli, R. (1999) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(99)00066-6 · Cited by 125

PHARMACOKINETICS OF DOXORUBICIN INCORPORATED IN SOLID LIPID NANOSPHERES (SLN)

Zara, G. P., Cavalli, R., Fundaro', A., Bargoni, A., Caputo, O., & Gasco, M. R. (1999) · Pharmacological Research · doi:10.1006/phrs.1999.0509 · Cited by 122

Magnetic and Photoresponsive Theranosomes: Translating Cell-Released Vesicles into Smart Nanovectors for Cancer Therapy

Silva, A., Kolosnjaj‐Tabi, J., Bonneau, S., Marangon, I., Boggetto, N., Aubertin, K., Clémеnt, O., Bureau, M. F., Luciani, N., Gazeau, F., et al. (2013) · ACS Nano · doi:10.1021/nn400269x · Cited by 119

Nanoneuromedicines for degenerative, inflammatory, and infectious nervous system diseases

Gendelman, H. E., Anantharam, V., Bronich, T. K., Ghaisas, S., Jin, H., Kanthasamy, A. G., Liu, X., McMillan, J., Mosley, R. L., Narasimhan, B., et al. (2015) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2014.12.014 · Cited by 118

Brain delivery of camptothecin by means of solid lipid nanoparticles: Formulation design, in vitro and in vivo studies

Martins, S., Tho, I., Reimold, I., Fricker, G., Souto, E. B., Ferreira, D., & Brandl, M. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.09.054 · Cited by 117

Solid Lipid Nanoparticle Formulations of Docetaxel Prepared with High Melting Point Triglycerides: In Vitro and in Vivo Evaluation

Naguib, Y. W., Rodriguez, B. L., Li, X., Hursting, S. D., Williams, R. O., & Cui, Z. (2014) · Molecular Pharmaceutics · doi:10.1021/mp4006968 · Cited by 117

Preparation and Enhanced Oral Bioavailability of Cryptotanshinone-Loaded Solid Lipid Nanoparticles

Hu, L., Xing, Q., Meng, J., & Shang, C. (2010) · AAPS PharmSciTech · doi:10.1208/s12249-010-9410-3 · Cited by 116

Physicochemical properties of nevirapine-loaded solid lipid nanoparticles and nanostructured lipid carriers

Kuo, Y., & Chung, J.-F. (2010) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2010.11.037 · Cited by 116

Dynamic Light Scattering Techniques and Their Applications in Food Science

Alexander, M., & Dalgleish, D. G. (2006) · Food Biophysics · doi:10.1007/s11483-005-9000-1 · Cited by 113

Formulation and optimization of solid lipid nanoparticles of buspirone HCl for enhancement of its oral bioavailability

Varshosaz, J., Tabbakhian, M., & Mohammadi, M. Y. (2009) · Journal of Liposome Research · doi:10.3109/08982100903443065 · Cited by 106

Corticosteroid solubility and lipid polarity control release from solid lipid nanoparticles

Jensen, L. B., Magnussson, E., Gunnarsson, L., Vermehren, C., Nielsen, H. M., & Petersson, K. (2009) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2009.10.022 · Cited by 105

Increased brain uptake of docetaxel and ketoconazole loaded folate-grafted solid lipid nanoparticles

Venishetty, V. K., Komuravelli, R., Kuncha, M., Sistla, R., & Diwan, P. V. (2012) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2012.03.003 · Cited by 104

Pharmacokinetics, tissue distribution and bioavailability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration

Manjunath, K., & Venkateswarlu, V. (2006) · Journal of drug targeting · doi:10.1080/10611860600888850 · Cited by 103

Phagocytic uptake of fluorescent stealth and non-stealth solid lipid nanoparticles

Bocca, C., Caputo, O., Cavalli, R., Gabriel, L., Miglietta, A., & Gasco, M. R. (1998) · International Journal of Pharmaceutics · doi:10.1016/s0378-5173(98)00282-8 · Cited by 99

Lipid emulsions as a novel system to reduce the hemolytic activity of lytic agents: mechanism of the protective effect

Jumaa, M., & Müller, B. W. (2000) · European Journal of Pharmaceutical Sciences · doi:10.1016/s0928-0987(99)00071-8 · Cited by 96

Solid Lipid Nanoparticles for Image-Guided Therapy of Atherosclerosis

Oumzil, K., Ramin, M. A., Lorenzato, C., Hémadou, A., Laroche‐Traineau, J., Jacobin‐Valat, M., Mornet, S., Roy, C.-E., Kauss, T., Gaudin, K., et al. (2016) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5b00590 · Cited by 92

Theranostic applications of mesoporous silica nanoparticles and their organic/inorganic hybrids

Chen, N., Cheng, S., Souris, J. S., Chen, C.-T., Mou, C., & Lo, L. (2013) · Journal of Materials Chemistry B · doi:10.1039/c3tb20249f · Cited by 86

Enhancement of oral bioavailability of pentoxifylline by solid lipid nanoparticles

Varshosaz, J., Minaiyan, M., & Moazen, E. (2010) · Journal of Liposome Research · doi:10.3109/08982100903161456 · Cited by 81

Scaling up feasibility of the production of solid lipid nanoparticles (SLN).

Gohla, S., & Dingler, A. (2001) · PubMed · Cited by 78

Solid lipid nanoparticles as potential tools for gene therapy: In vivo protein expression after intravenous administration

del Pozo‐Rodríguez, A., Delgado, D., Solinís, M. Á., Pedraz, J. L., Echevarrı́a, E., Rodríguez, J. M., & Rodríguez‐Gascón, A. (2009) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2009.10.020 · Cited by 77

β-Hydroxybutyric acid grafted solid lipid nanoparticles: A novel strategy to improve drug delivery to brain

Venishetty, V. K., Samala, R., Komuravelli, R., Kuncha, M., Sistla, R., & Diwan, P. V. (2012) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2012.08.004 · Cited by 73

Preparation and Optimization of Triptolide-Loaded Solid Lipid Nanoparticles for Oral Delivery with Reduced Gastric Irritation

Zhang, C., Gu, C., Fan, P., Liu, W., Wan, J., Xu, H., Lam, C. W. K., & Yang, X. (2013) · Molecules · doi:10.3390/molecules181113340 · Cited by 71

Formulation, Characterization and Pharmacokinetics of Praziquantel-Loaded Hydrogenated Castor Oil Solid Lipid Nanoparticles

Xie, S., Pan, B., Wang, M., Zhu, L., Wang, F., Dong, Z., Wang, X., & Zhou, W. (2010) · Nanomedicine · doi:10.2217/nnm.10.42 · Cited by 70

Amphotericin B loaded solid lipid nanoparticles (SLNs) and nanostructured lipid carrier (NLCs): physicochemical and solid-solution state characterizations

Jansook, P., Fülöp, Z., & Ritthidej, G. C. (2019) · Drug Development and Industrial Pharmacy · doi:10.1080/03639045.2019.1569023 · Cited by 67

Coaxial Electrohydrodynamic Spraying: A Novel One-Step Technique To Prepare Oligodeoxynucleotide Encapsulated Lipoplex Nanoparticles

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Design and Characterization of Glyceryl Monostearate Solid Lipid Nanoparticles Prepared by High Shear Homogenization

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DNA delivery via cationic solid lipid nanoparticles (SLNs)

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Cancer Targeting Potential of Folate Targeted Nanocarrier under Comparative Influence of Tretinoin and Dexamethasone

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Effect of Omega-3 Fatty Acids on Crystallization, Polymorphic Transformation and Stability of Tripalmitin Solid Lipid Nanoparticle Suspensions

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Preparation and characterization of ibuprofen solid lipid nanoparticles with enhanced solubility

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Cationic lipid nanosystems as carriers for nucleic acids

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Baclofen-loaded solid lipid nanoparticles: Preparation, electrophysiological assessment of efficacy, pharmacokinetic and tissue distribution in rats after intraperitoneal administration

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Diflucortolone valerate loaded solid lipid nanoparticles as a semisolid topical delivery system

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Implications of formulation design on lipid-based nanostructured carrier system for drug delivery to brain

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Adsorption of Non-Ionic Surfactants on Hydrophobic Silica Particles and the Stability of the Corresponding Aqueous Dispersions

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Controlled Drug Delivery Systems: Current Status and Future Directions

Adepu, S., & Ramakrishna, S. (2021) · Molecules · doi:10.3390/molecules26195905 · Cited by 1,691

Lipid-Based Nanoparticles for Drug/Gene Delivery: An Overview of the Production Techniques and Difficulties Encountered in Their Industrial Development

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Lipid-Based Nanoparticles in the Clinic and Clinical Trials: From Cancer Nanomedicine to COVID-19 Vaccines

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Recent Progress in Nanostructured Smart Drug Delivery Systems for Cancer Therapy: A Review

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Advancements in nanoparticle-based treatment approaches for skin cancer therapy

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An Updated Review on Preparation and Characterization of Solid Lipid Nanoparticles

Ahmad, W., & Jawed, R. (2022) · Asian Journal of Pharmacy and Technology · doi:10.52711/2231-5713.2022.00051 · Cited by 3

Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: applications, advantages and disadvantages

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A Review On Pharmacological Action, Techniques And Stability Study Of Solid Lipid Nanoparticles

Singh, S. S., Verma, V. K., & Singh, N. (2023) · Journal of Survey in Fisheries Sciences · doi:10.53555/sfs.v10i1.1501

Advancements in drug delivery: The role of solid lipid nanoparticles and nanostructured lipid carriers

Rout, T. K., Sahu, J., Kulkarni, P. P., Shaw, R. K., Sahoo, S., Sahoo, C., Patsani, A., & Patra, H. (2026) · International Journal of Pharmacy and Pharmaceutical Science · doi:10.33545/26647222.2026.v8.i2a.306

Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Emerging Lipid Based Drug Delivery Systems

Shirodkar, R. K., Kumar, L., Mutalik, S., & Lewis, S. A. (2019) · Pharmaceutical Chemistry Journal · doi:10.1007/s11094-019-02017-9 · Cited by 123