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Salvinorin, a new trans-neoclerodane diterpene from Salvia divinorum(Labiatae)
Abstract
Salvinorin, isolated from Salvia divinorum, has been shown by spectroscopic and X-ray-crystallographic methods to be a trans-neoclerodane diterpene of structure (1). Crystals of compound (1) are orthorhombic, space group P212121 with a= 6.368(2), b= 11.338(3), c= 30.710(6)Å, and Z= 4. The structure was refined by leastsquares to R 0.052 and R′ 0.056.
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Citations
Cited by
Salvinorin A: A potent naturally occurring nonnitrogenous κ opioid selective agonist
Roth, B. L., Baner, K., Westkaemper, R., Siebert, D., Rice, K. C., Steinberg, S., Ernsberger, P., & Rothman, R. B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.182234399 · Cited by 784
Salvia divinorum and salvinorin A: new pharmacologic findings
Siebert, D. J. (1994) · Journal of Ethnopharmacology · doi:10.1016/0378-8741(94)90116-3 · Cited by 279
Clerodane diterpenes: sources, structures, and biological activities
Li, R., Morris-Natschke, S. L., & Lee, K.-H. (2016) · Natural Product Reports · doi:10.1039/c5np00137d · Cited by 256
Clinical applications of hallucinogens: a review
Garcia-Romeu, A., Kersgaard, B., & Addy, P. H. (2016) · Experimental and Clinical Psychopharmacology · doi:10.1037/pha0000084 · Cited by 201
Pattern of use and subjective effects of Salvia divinorum among recreational users
González, D., Riba, J., Bouso, J. C., Gómez-Jarabo, G., & Barbanoj, M. J. (2006) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2006.04.001 · Cited by 163
Metadata
- Authors
- Ortega, A., Blount, J. F., & Manchand, P. S.
- Venue
- Journal of the Chemical Society, Perkin Transactions 1
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 1982
- Pages
- 2505
- ISSN
- 1364-5463 (ISSN-L)
- 0300-922X
- OpenAlex
- W2083661078
- Cited by
- 226
- References
- 0
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ortega, A., Blount, J. F., & Manchand, P. S. (1982). Salvinorin, a new trans-neoclerodane diterpene from Salvia divinorum(Labiatae). Journal of the Chemical Society, Perkin Transactions 1. https://doi.org/10.1039/p19820002505
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
