Cited by 256Biochemical Acid Research StudiesMitochondrial Function and PathologyMicrobial metabolism and enzyme function

The oxidation of pyruvate in pigeon breast muscle

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Krebs, Hans Adolf, Eggleston, Leonard Victor·1940·Biochemical Journal

Abstract

PYRUVATE is very readily oxidized in animal tissues, yet little is known about the immediate products of its oxidation.Such oxidative reactions of pyruvate as are known to occur-dismutation, formation of succinate, acetate or ketone bodies-are side reactions whose significance varies from tissue to tissue: in no tissue can these reactions account for the total oxidation, and in some tissues,

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Crossref · 10.1042/bj0340442

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  • Krebs determined that the two carbon atoms that condensed with OAA to form citrate were derived from pyruvate and that oxygen consumption in muscle increases when pyruvate is added.

    “In subsequent work, Krebs (4) determined that the two carbon atoms that condensed with OAA to form citrate were derived from pyruvate and that oxygen consumption in muscle increases when pyruvate is added.”

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Research works printed but not linked: 1

  1. Stare & Baumann (1936). Proc. Roy. Soc. B, 121, 338.

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Authors
Krebs, H. A., & Eggleston, L. V.
Affiliations
University of Sheffield (GB)
Venue
Biochemical Journal
Published
1940-03-01
Volume
34
Issue
3
Pages
442-459
ISSN
0306-3283 (ISSN-L)
OpenAlex
W80730550
Cited by
256
References
9
Citations by year
2026: 2 · 2025: 3 · 2023: 3 · 2022: 5 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 2 · 2014: 2
FWCI
10.38
Type
journal article
Language
en
Open access
Locations
  • Biochemical Journal (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Biochemical Acid Research Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial metabolism and enzyme function
Keywords
pyruvate oxidation, pigeon breast muscle, oxidative metabolism, pyruvate dehydrogenase, pyruvate dehydrogenase complex, acetate production, ketone bodies, muscle metabolism

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