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Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats
Open accessAbstract
Plasma insulin concentrations in fed rats were altered acutely by administration of glucose or anti-insulin serum. Rates of fatty acid synthesis in adipose tissue and liver were estimated from the incorporation of 3H from 3H2O. In the adipose tissue dehydrogenase and acetyl-CoA carboxylase were evident. In liver, although changes in rates of fatty acid synthesis were found, the initial activity of pyruvate dehydrogenase did not alter, but small parallel changes in acetyl-CoA carboxylase activity were observed.
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Cited by
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Carbó, N., López-Soriano, J., Costelli, P., Alvarez, B., Busquets, S., Baccino, F. M., Quinn, L. S., López-Soriano, F. J., & Argilés, J. M. (2001) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(00)00188-4 · Cited by 174
Figueras, M., Olivan, M., Busquets, S., López‐Soriano, F. J., & Argilés, J. M. (2011) · Obesity · doi:10.1038/oby.2010.194 · Cited by 113
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Decreased fatty acid synthesis due to mitochondrial uncoupling in adipose tissue
Rossmeisl, M., Syrový, I., Baumruk, F., Flachs, P., Janovska, P., & Kopecký, J. (2000) · The FASEB Journal · doi:10.1096/fj.99-0965com · Cited by 89
Metadata
- Authors
- Stansbie, D., Brownsey, R. W., Crettaz, M., & Denton, R. M.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1976-11-15
- Volume
- 160
- Issue
- 2
- Pages
- 413-416
- ISSN
- 0306-3283 (ISSN-L)
- OpenAlex
- W1902395899
- Cited by
- 352
- References
- 0
- FWCI
- 3.20
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats. https://app.cochat.ai/papers/10.1042/bj1600413
- The paper
- Stansbie, D., Brownsey, R. W., Crettaz, M., & Denton, R. M. (1976). Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats. Biochemical Journal. https://doi.org/10.1042/bj1600413
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
