The specificities of protein kinase inhibitors: an update

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Items 301–400 of 1,000

1. Regulation of p73-mediated apoptosis by c-Jun N-terminal kinase
   Emma V. Jones, Mark J. Dickman, Alan J. Whitmarsh · 2007 · Biochemical Journal
2. Inverse In Silico Screening for Identification of Kinase Inhibitor Targets
   Stefan Zahler A, Simon Tietze, Frank Totzke, Michael H.G. Kubbutat, Laurent Meijer, Angelika M. Vollmar, Joannis Apostolakis · 2007 · Chemistry & Biology
3. Signalling pathways involved in multisite phosphorylation of the transcription factor ATF‐2
   Simon Morton, Roger J. Davis, Philip Cohen · 2004 · FEBS Letters
4. Pharmacology of Modulators of Alternative Splicing
   David O. Bates, Jonathan C. Morris, Sebastian Oltean, Lucy Frances Donaldson · 2016 · Pharmacological Reviews
5. Rapid Structure-Activity and Selectivity Analysis of Kinase Inhibitors by BioMAP Analysis in Complex Human Primary Cell-Based Models
   E. Kunkel, I. Plavec, Dat Nguyen, Jennifer E. Melrose, E. Rosler, L. Kao, Yuk-Er Wang, E. Hytopoulos, Anthony C. Bishop, R. Bateman et al. · 2004 · Assay and drug development technologies
6. Not just inductive: a crucial mechanical role for the endoderm during heart tube assembly
   Victor D. Varner, Larry A. Taber · 2012 · Development
7. AML1/RUNX1 Phosphorylation by Cyclin-Dependent Kinases Regulates the Degradation of AML1/RUNX1 by the Anaphase-Promoting Complex
   Joseph R. Biggs, Luke F. Peterson, Youhong Zhang, Andrew S. Kraft, Dong‐Er Zhang · 2006 · Molecular and Cellular Biology
8. Prothoracicotropic Hormone
   Wendy A. Smith, Robert Rybczynski · 2011 · Elsevier eBooks
9. Regulation of myosin phosphorylation and myofilament Ca2+ sensitivity in vascular smooth muscle
   Katsuya Hirano, Mayumi Hirano, Hideo Kanaide · 2004 · Journal of Smooth Muscle Research
10. c-Jun N-terminal Kinase (JNK) Positively Regulates NFATc2 Transactivation through Phosphorylation within the N-terminal Regulatory Domain
    Inmaculada Ortega‐Pérez, Eva Cano, Felipe Were, Margarita Villar, Jesús Vázquez, Juan Miguel Redondo · 2005 · Journal of Biological Chemistry
11. Characterization of vinblastine-induced Bcl-xL and Bcl-2 phosphorylation: evidence for a novel protein kinase and a coordinated phosphorylation/dephosphorylation cycle associated with apoptosis induction
    Lihua Du, Christopher S. Lyle, Timothy C. Chambers · 2004 · Oncogene
12. Cyclin/CDK Regulates the Nucleocytoplasmic Localization of the Human Papillomavirus E1 DNA Helicase
    Wentao Deng, Biing Yuan Lin, Ge Jin, Crystal G. Wheeler, Tianlin Ma, J. Wade Harper, Thomas R. Broker, Louise T. Chow · 2004 · Journal of Virology
13. Selective DYRK1A Inhibitor for the Treatment of Type 1 Diabetes: Discovery of 6-Azaindole Derivative GNF2133
    Yahu A. Liu, Qihui Jin, Yefen Zou, Qiang Ding, Shanshan Yan, Zhicheng Wang, Xueshi Hao, Bao Nguyen, Xiaoyue Zhang, Jianfeng Pan et al. · 2020 · Journal of Medicinal Chemistry
14. Acrolein Induces Heme Oxygenase-1 through PKC-δ and PI3K in Human Bronchial Epithelial Cells
    Hongqiao Zhang, Henry Jay Forman · 2007 · American Journal of Respiratory Cell and Molecular Biology
15. Mechanical factors activateß‐catenin‐dependent oncogene expression in APC1638N/+mouse colon
    Joanne Whitehead, Danijela Matic Vignjevic, Claus Fütterer, Emmanuel Beaurepaire, Sylvie Robine, Emmanuel Farge · 2008 · HFSP journal
16. GPIb-dependent platelet activation is dependent on Src kinases but not MAP kinase or cGMP-dependent kinase
    Stuart J. Marshall, Yotis A. Senis, Jocelyn M. Auger, Robert Feil, Franz Bruno Hofmann, Gary P. Salmon, Janet T. Peterson, Frank Burslem, Steve P. Watson · 2003 · Blood
17. Actin Filament Elasticity and Retrograde Flow Shape the Force-Velocity Relation of Motile Cells
    Juliane Zimmermann, Claudia A. Brunner, Mihaela Enculescu, Michael Goegler, Allen J. Ehrlicher, Josef Alfons Käs, Martin Falcke · 2012 · Biophysical Journal
18. RNA splicing: A New Paradigm in Host-Pathogen Interactions
    K. Chauhan, Haroon Kalam, Ravi Dutt, Dhiraj Kumar · 2019 · Journal of Molecular Biology
19. Prospects for Improving Brain Function in Individuals with Down Syndrome
    Alberto C. S. Costa, Jonah J. Scott-McKean · 2013 · CNS Drugs
20. Dyrk1A Inhibition as Potential Treatment for Alzheimer’S Disease
    Silvia Stotani, Fabrizio Giordanetto, Federico Medda · 2016 · Future Medicinal Chemistry
21. IL-1β and TNF-α Regulation of the Adenosine Receptor (A2A) Expression: Differential Requirement for NF-κB Binding to the Proximal Promoter
    Silvana Morello, Kazuhiro Ito, Satoshi Yamamura, Kang‐Yun Lee, Elen Jazrawi, Patricia deSouza, Peter John Barnes, Carla Cicala, Ian Michael Adcock · 2006 · The Journal of Immunology
22. Molecular mechanisms involved in cochlear implantation trauma and the protection of hearing and auditory sensory cells by inhibition of c‐jun‐N‐terminal kinase signaling
    Adrien A. Eshraghi, Chhavi Gupta, Thomas R. Van De Water, Jorge E. Bohorquez, Carolyn Garnham, Esperanza Bas, Victoria Maria Talamo · 2013 · The Laryngoscope
23. Self-Reporting Fluorescent Substrates of Protein Tyrosine Kinases
    Qunzhao Wang, Sean M. Cahill, Michael Blumenstein, David S. Lawrence · 2006 · Journal of the American Chemical Society
24. A Coiled-Coil Enabled Split-Luciferase Three-Hybrid System: Applied Toward Profiling Inhibitors of Protein Kinases
    Benjamin W. Jester, Kurt J. Cox, Alicia Gaj, Carolyn D. Shomin, Jason R. Porter, Indraneel Ghosh · 2010 · Journal of the American Chemical Society
25. Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease
    Byoung Dae Lee, Valina Lynn Dawson, Ted M. Dawson · 2012 · Trends in Pharmacological Sciences
26. Cross-talk between the p38α and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation
    Christopher J. Staples, David M. Owens, Jana V. Maier, Andrew C.B. Cato, Stephen M. Keyse · 2010 · Journal of Biological Chemistry
27. Physiological Concentrations of Insulin Induce Endothelin-Dependent Vasoconstriction of Skeletal Muscle Resistance Arteries in the Presence of Tumor Necrosis Factor-α Dependence on c-Jun N-Terminal Kinase
    Etto C. Eringa, Coen D.A. Stehouwer, Kimberley V. Walburg, Andrew D. Clark, Geerten P. van Nieuw Amerongen, Nico Westerhof, P. Sipkema · 2005 · Arteriosclerosis Thrombosis and Vascular Biology
28. AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes
    Justin M. Summy, Jose Gilberto Trevino, Donald P. Lesslie, Cheryl Hunt Baker, William C. Shakespeare, Yihan Wang, Raji Sundaramoorthi, Chester A. Metcalf, Jeffrey A. Keats, Tomi K. Sawyer et al. · 2005 · Molecular Cancer Therapeutics
29. Interactions of LY333531 and Other Bisindolyl Maleimide Inhibitors with PDK1
    David Komander, Gursant S. Kular, Alexander W. Schüttelkopf, Mária Deák, K.R.C. Prakash, Jennifer Bain, Matthew Elliott, Marta Garrido-Franco, Alan P. Kozikowski, Dario R. Alessi et al. · 2004 · Structure
30. Dyrk1a from gene function in development and physiology to dosage correction across life span in down syndrome
    Atas-Ozcan, Helin, Brault, Véronique, Duchon, Arnaud, Herault, Yann · 2021 · Genes
31. Molecular basis of pharmacotherapies for cognition in Down syndrome
    K. Gardiner · 2009 · TIPS - Trends in Pharmacological Sciences
32. Mitogen activated protein kinase inhibitors: where are we now and where are we going?
    Susan E. Sweeney, Gary S. Firestein · 2006 · Annals of the Rheumatic Diseases
33. Inhibiting Myosin Light Chain Kinase Induces Apoptosis In Vitro and In Vivo
    Fabeha Fazal, Lianzhi Gu, Ivanna Ihnatovych, Yoo-Jeong Han, Wen‐Yang Hu, Nenad Antic, Fernando Carreira, James F. Blomquist, Thomas J. Hope, David S. Ucker et al. · 2005 · Molecular and Cellular Biology
34. Chemical Proteomic Analysis Reveals Alternative Modes of Action for Pyrido[2,3-d]pyrimidine Kinase Inhibitors
    Josef B. Wissing, Klaus Godl, Dirk Brehmer, Stephanie Blencke, Martina Weber, Peter Habenberger, Matthias Stein-Gerlach, Andrea Missio, Matthew L. Cotten, Stefan Müller et al. · 2004 · Molecular & Cellular Proteomics
35. Modeling pattern formation in hydra: a route to understanding essential steps in development
    Hans Meinhardt · 2012 · The International Journal of Developmental Biology
36. Structures of P. falciparum Protein Kinase 7 Identify an Activation Motif and Leads for Inhibitor Design
    Anaïs Merckx, Aude Echalier, Kia Langford‐Smith, Audrey Sicard, Gordon Langsley, Jos Joore, Christian Doerig, Martin E. M. Noble, Jane Endicott · 2008 · Structure
37. A unique type of GSK-3 inhibitor brings new opportunities to the clinic
    Avital Licht-Murava, Rom Paz, Lilach Vaks, Limor Avrahami, Batya Plotkin, Miriam Eisenstein, Hagit Eldar-Finkelman · 2016 · Science Signaling
38. Development of Kinase-Selective, Harmine-Based DYRK1A Inhibitors that Induce Pancreatic Human β-Cell Proliferation
    Kunal Kumar, Peng Wang, Roberto Sánchez, Ethan Swartz, Andrew F. Stewart, Robert J. DeVita · 2018 · Journal of Medicinal Chemistry
39. Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression
    Fabio Carrozzino, Paolo Pugnale, Eric Féraille, Roberto Montesano · 2009 · American Journal of Physiology-Cell Physiology
40. α1- and β1-Adrenoceptor Signaling Fully Compensates for β3-Adrenoceptor Deficiency in Brown Adipocyte Norepinephrine-Stimulated Glucose Uptake
    Ekaterina Chernogubova, Dana S. Hutchinson, Jan Nedergaard, Tore Bengtsson · 2005 · Endocrinology
41. Chlamydia trachomatis tarp is phosphorylated by src family tyrosine kinases
    Travis J. Jewett, Cheryl A. Dooley, David J. Mead, Ted Hackstadt · 2008 · Biochemical and Biophysical Research Communications
42. Current pharmacotherapy and putative disease-modifying therapy for Alzheimer’s disease
    Akanksha Kulshreshtha, Poonam Piplani · 2016 · Neurological Sciences
43. 3,5-Diphenylpent-2-enoic Acids as Allosteric Activators of the Protein Kinase PDK1: Structure−Activity Relationships and Thermodynamic Characterization of Binding as Paradigms for PIF-Binding Pocket-Targeting Compounds†PDB code of 2Z with PDK1: 3HRF.
    Adriana Stroba, Francis Schaeffer, Valérie Hindie, Laura A. Lopez-Garcia, Iris Adrian, Wolfgang Fröhner, Rolf W. Hartmann, Ricardo M. Biondi, Matthias Engel · 2009 · Journal of Medicinal Chemistry
44. Paclitaxel (Taxol) upregulates expression of functional interleukin-6 in human ovarian cancer cells through multiple signaling pathways
    Wang Th, Y-H Chan, CW Chen, W-H Kung, Y-S Lee, ST Wang, T-C Chang, HS Wang · 2006 · Oncogene
45. β-Catenin–dependent mechanotransduction dates back to the common ancestor of Cnidaria and Bilateria
    Ekaterina Pukhlyakova, Andrew J. Aman, Kareem Elsayad, Ulrich Technau · 2018 · Proceedings of the National Academy of Sciences
46. Crystal Structures of Active Src Kinase Domain Complexes
    Christine B. Breitenlechner, Norman Kairies, Konrad Honold, Stefan Scheiblich, Hans Koll, Eva Greiter, S. Koch, Wolfgang Schäfer, Robert Huber, Richard Alan Engh · 2005 · Journal of Molecular Biology
47. Is it possible to improve neurodevelopmental abnormalities in Down syndrome?
    Renata Bartesaghi, Sandra Guidi, Elisabetta Ciani · 2011 · Reviews in the Neurosciences
48. cGMP-Dependent Protein Kinases as Potential Targets for Colon Cancer Prevention and Treatment
    Darren D. Browning, In‐Kiu Kwon, Rui Wang · 2009 · Future Medicinal Chemistry
49. Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages
    Maria Smolinska, Nicole J. Horwood, Theresa H. Page, Tim Smallie, Brian M. J. Foxwell · 2007 · Molecular Immunology
50. Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models
    Benoît Souchet, Fayçal Guedj, Zsuza Penke-Verdier, Fabrice Daubigney, Arnaud Duchon, Yann Hérault, Jean‐Charles Bizot, Nathalie Janel, Nicole Créau, Benoı̂t Delatour et al. · 2015 · Frontiers in Behavioral Neuroscience
51. Dishevelled-1 and dishevelled-3 affect cell invasion mainly through canonical and noncanonical Wnt pathway, respectively, and associate with poor prognosis in nonsmall cell lung cancer
    Yue Zhao, Zhiqiang Yang, Yan Wang, Yuan Miao, Yang Liu, Shun‐Dong Dai, Yang Han, Enhua Wang · 2010 · Molecular Carcinogenesis
52. Development of DANDYs, New 3,5-Diaryl-7-azaindoles Demonstrating Potent DYRK1A Kinase Inhibitory Activity
    Stéphanie Gourdain, Julien Dairou, Clément Denhez, Linh Chi Bui, Fernando Rodrigues‐Lima, Nathalie Janel, Jean Maurice Delabar, Kevin Cariou, Robert H. Dodd · 2013 · Journal of Medicinal Chemistry
53. Matrix Metalloproteinase-2 Expression by Vascular Smooth Muscle Cells Is Mediated by Both Stimulatory and Inhibitory Signals in Response to Growth Factors
    George Mitchell Risinger, Tamara S. Hunt, Dawn L. Updike, Elizabeth C. Bullen, Eric W. Howard · 2006 · Journal of Biological Chemistry
54. An Essential Role for the Integrin-Linked Kinase–Glycogen Synthase Kinase-3β Pathway during Dendrite Initiation and Growth
    Sibel Naska, Katya J. Park, Gregory Edward Hannigan, Shoukat Dedhar, Freda D. Miller, David R. Kaplan · 2006 · Journal of Neuroscience
55. Identification of Selective Inhibitors of NAD+-dependent Deacetylases Using Phenotypic Screens in Yeast
    Maki Hirao, Jeff Posakony, Melisa Nelson, Henning Hruby, Manfred Jung, Julian A. Simon, Antonio Bedalov · 2003 · Journal of Biological Chemistry
56. Localization of PTP-1B, SHP-2, and Src Exclusively in Rat Brain Mitochondria and Functional Consequences
    Amal Arachiche, Olivier Augereau, Marion Décossas, Claire Pertuiset, Étienne Gontier, Thierry Letellier, Jeanne Dachary-Prigent · 2008 · Journal of Biological Chemistry
57. Advances in Therapeutics for Neurodegenerative Tauopathies: Moving toward the Specific Targeting of the Most Toxic Tau Species
    Julia E. Gerson, Diana Laura Castillo‐Carranza, Rakez Kayed · 2014 · ACS Chemical Neuroscience
58. Hypoxia alters biophysical properties of endothelial cells via p38 MAPK- and Rho kinase-dependent pathways
    Steven S. An, Corin M. Pennella, Achuta Gonnabathula, Jianxin Chen, Ning Wang, Matthias Gaestel, Paul M. Hassoun, Jeffrey J. Fredberg, Usamah S. Kayyali · 2005 · American Journal of Physiology-Cell Physiology
59. Cell Cycle-Dependent Phosphorylation of C/EBPβ Mediates Oncogenic Cooperativity between C/EBPβ and H-RasV12
    Jon D. Shuman, Thomas B. Sebastian, Philipp Kaldis, Terry D. Copeland, Songyun Zhu, Robert C. Smart, Peter Frederick Johnson · 2004 · Molecular and Cellular Biology
60. BDNF ‐mediated regulation of ethanol consumption requires the activation of the MAP kinase pathway and protein synthesis
    Jérôme Jeanblanc, Marian L. Logrip, Patricia H. Janak, Dorit Ron A · 2012 · European Journal of Neuroscience
61. Identification of c‐Src tyrosine kinase substrates in platelet‐derived growth factor receptor signaling
    Ramars Amanchy, Jun Zhong, Rosa Hong, James H. Kim, Marjan Guček, Robert Norman Cole, Henrik Molina, Akhilesh Pandey · 2009 · Molecular Oncology
62. Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells
    J-C Cheng, H-M. Chang, Peter C. K. Leung · 2012 · Oncogene
63. Five Years of Progress on Cyclin-Dependent Kinases and other Cellular Proteins as Potential Targets for Antiviral Drugs
    Luis M. Schang, Mireille St. Vincent, Jonathan J Lacasse · 2006 · Antiviral chemistry & chemotherapy
64. Differential regulation of platelet‐derived growth factor stimulated migration and proliferation in osteoblastic cells
    Meenal Mehrotra, Stephen M. Krane, Kristen Walters, Carol Coke Pilbeam · 2004 · Journal of Cellular Biochemistry
65. Cigarette smoke extract stimulates epithelial–mesenchymal transition through Src activation
    Hongqiao Zhang, Honglei Liu, Zea Borok, Kelvin J.A. Davies, Fulvio Ursini, Henry Jay Forman · 2012 · Free Radical Biology and Medicine
66. Distinct Stimulus-Specific Histone Modifications at Hsp70 Chromatin Targeted by the Transcription Factor Heat Shock Factor-1
    Stuart Thomson, Angela Hollis, Catherine A. Hazzalin, Louis C. Mahadevan · 2004 · Molecular Cell
67. EGFR-dependent mechanisms in glioblastoma: towards a better therapeutic strategy
    Cristina Zahonero, Pilar Sánchez‐Gómez · 2014 · Cellular and Molecular Life Sciences
68. Stimulation of the Epithelial Sodium Channel (ENaC) by cAMP Involves Putative ERK Phosphorylation Sites in the C Termini of the Channel's β- and γ-Subunit
    Li-Min Yang, Ralf Rinke, Christoph Korbmacher · 2006 · Journal of Biological Chemistry
69. DYRK1A inhibition and cognitive rescue in a Down syndrome mouse model are induced by new fluoro-DANDY derivatives
    Neumann, Fernanda, Gourdain, Stéphanie, Albac, Christelle, Dekker, Alain D., Bui, Linh Chi, Dairou, Julien, Schmitz-Afonso, Isabelle, Hue, Nathalie, Rodrigues-Lima, Fernando, Delabar, Jean M. et al. · 2018 · Scientific Reports
70. Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship
    Hezhen Wang, Zhiyuan Wang, Chunyong Wei, Jing Wang, Yingshu Xu, Guohui Bai, Qizheng Yao, Lei Zhang, Yong‐Zheng Chen · 2021 · European Journal of Medicinal Chemistry
71. Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress
    Daisuke Matsuda, Yuji Nakayama, Shinya Horimoto, Takahisa Kuga, Kikuko Ikeda, Kousuke Kasahara, Naoto Yamaguchi · 2006 · Experimental Cell Research
72. Extracellular matrix regulates human airway smooth muscle cell migration
    K. Parameswaran, Katherine Radford, J. Zuo, Luke Jeffrey Janssen, Paul M. O’Byrne, Gerard Cox · 2004 · European Respiratory Journal
73. DYRK1A Kinase Inhibitors with Emphasis on Cancer
    A. Ionescu, F. Dufrasne, Michel Gelbcke, Ivan Jabin, Robert Kiss A, Delphine Lamoral‐Theys · 2012 · Mini-Reviews in Medicinal Chemistry
74. Melatonin promotes sheep Leydig cell testosterone secretion in a co-culture with Sertoli cells
    Shoulong Deng, Zhipeng Wang, Cheng Jin, Xiaolong Kang, Aalia Batool, Yan Zhang, Xiaoyu Li, Xiuxia Wang, Su‐Ren Chen, Chawnshang Chang et al. · 2017 · Theriogenology
75. Requirement of the MAP kinase signaling pathways for mouse preimplantation development
    Momoko Maekawa, Takuya Yamamoto, Takuji Tanoue, Yasuhito Yuasa, Osamu Chisaka, Eisuke Nishida · 2005 · Development
76. The diverse functions of Src family kinases in macrophages
    L. Abram Clare · 2008 · Frontiers in bioscience
77. Anti-inflammatory actions of Syk inhibitors in macrophages involve non-specific inhibition of toll-like receptors-mediated JNK signaling pathway
    Ying‐Cing Lin, Duen-Yi Huang, Ching‐Liang Chu, Wan‐Wan Lin · 2010 · Molecular Immunology
78. Myosin Light Chain Kinase Inhibition: Correction of Increased Intestinal Epithelial Permeability In Vitro
    Linda M. Feighery, Sean W. Cochrane, Teresa Quinn, Alan W. Baird, Daniel P. O’Toole, Siân E. Owens, Diarmuid P. O’Donoghue, Randall J. Mrsny, David J. Brayden · 2007 · Pharmaceutical Research
79. Wnt Signaling Activates Shh Signaling in Early Postnatal Intervertebral Discs, and Re-Activates Shh Signaling in Old Discs in the Mouse
    Tamara Winkler, Eric J. Mahoney, Debora I. Sinner, Christopher C. Wylie, Chitra Lekha Dahia · 2014 · PLoS ONE
80. Phosphorylation of Amphiphysin I by Minibrain Kinase/Dual-specificity Tyrosine Phosphorylation-regulated Kinase, a Kinase Implicated in Down Syndrome
    Noriko Murakami, Wen Qin Xie, Renné Chen Lu, Mo‐Chou Chen‐Hwang, Andrzej Wieraszko, Yu Wen Hwang · 2006 · Journal of Biological Chemistry
81. Inhibition of Tumor Growth, Angiogenesis, and Tumor Cell Proliferation by a Small Molecule Inhibitor of c-Jun N-terminal Kinase
    Bruce W. Ennis, Kimberly E. Fultz, Kent A. Smith, John K. Westwick, Dan Zhu, Michael Boluro-Ajayi, Graham K. Bilter, Bernd Stein · 2005 · Journal of Pharmacology and Experimental Therapeutics
82. A Model for the Recognition of Protein Kinases Based on the Entropy of 3D van der Waals Interactions
    Humberto González‐Díaz, Liane Saı́z-Urra, Reinaldo Molina, Lourdes Santana, Eugenio Uriarte · 2006 · Journal of Proteome Research
83. p 38 MAPK in cardioprotection – are we there yet?
    Eva Denise Martin, R Bassi, Michael S. Marber · 2014 · British Journal of Pharmacology
84. CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells
    Claire Delehouzé, Klaus Godl, Nadège Loaëc, Céline Bruyère, Nathalie Desban, Nassima Oumata, Hervé Galons, Theodoros I. Roumeliotis, Ευγενία Γιαννοπούλου, Jose A. Grenet et al. · 2013 · Oncogene
85. Effects of pharmacological cyclin-dependent kinase inhibitors on viral transcription and replication
    Luis M. Schang · 2003 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
86. Natural Product-Derived Small Molecule Activators of Hypoxia-Inducible Factor-1 (HIF-1)
    Dale G. Nagle, Yudong Zhou · 2006 · Current Pharmaceutical Design
87. c-Jun N-terminal kinase pathways in diabetes
    Ruojing Yang, James M. Trevillyan · 2008 · The International Journal of Biochemistry & Cell Biology
88. Tinkering Outside the Kinase ATP Box: Allosteric (Type IV) and Bivalent (Type V) Inhibitors of Protein Kinases
    Kurt J. Cox, Carolyn D. Shomin, Indraneel Ghosh · 2010 · Future Medicinal Chemistry
89. Aberrant Splicing of Cyclin-Dependent Kinase–Associated Protein Phosphatase KAP Increases Proliferation and Migration in Glioblastoma
    Yi Yu, Xiuli Jiang, Bradley S. Schoch, Rona Stephanie Carroll, Peter McL. Black, Mark D. Johnson · 2007 · Cancer Research
90. Cooperation between antioxidants and 1,25‐dihydroxyvitamin D3 in induction of leukemia HL60 cell differentiation through the JNK/AP‐1/Egr‐1 pathway
    Qing Wang, Hagar Salman, Michael Danilenko, George P. Studzinski · 2005 · Journal of Cellular Physiology
91. Organization of mammary epithelial cells into 3D acinar structures requires glucocorticoid and JNK signaling
    Janice Murtagh, Emmett McArdle, Emer Gilligan, Laura Thornton, Fiona M. Furlong, Finian Martin · 2004 · The Journal of Cell Biology
92. Identification of Chemical Inhibitors to Human Tissue Transglutaminase by Screening Existing Drug Libraries
    Thung‐S. Lai, Yusha Katie Liu, Tim Tucker, Kurt R. Daniel, David C. Sane, Eric J. Toone, James R. Burke, Warren J. Strittmatter, Charles S. Greenberg · 2008 · Chemistry & Biology
93. JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
    Mónica Gumá, Jun‐ichi Kashiwakura, Brian Crain, Yuko Kawakami, Bruce Beutler, Gary S. Firestein, Toshiaki Kawakami, Michael Karin, Maripat Corr · 2010 · Proceedings of the National Academy of Sciences
94. Vitamin D3-driven signals for myeloid cell differentiation—Implications for differentiation therapy
    Philip Hughes, Ewa Marcinkowska, Elżbieta Gocek, George P. Studzinski, Geoffrey Brown · 2009 · Leukemia Research
95. Using Chemical Genetics and ATP Analogues To Dissect Protein Kinase Function
    Lucy M. Elphick, Sarah Emerson Lee, Véronique Gouverneur, David J. Mann · 2007 · ACS Chemical Biology
96. Different Mitogen-Activated Protein Kinase-Dependent Cytokine Responses in Cells of the Monocyte Lineage
    Susan J. Tudhope, Tricia K. Finney‐Hayward, Andrew Gordon Nicholson, Ruth J. Mayer, Mary S. Barnette, Peter John Barnes, Louise Donnelly · 2007 · Journal of Pharmacology and Experimental Therapeutics
97. Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors: a survey of recent patent literature
    Thu Lan Nguyen, Corinne Fruit, Yann Hérault, Laurent Meijer, Thierry Besson · 2017 · Expert Opinion on Therapeutic Patents
98. Critical Role for Hematopoietic Cell Kinase (Hck)-mediated Phosphorylation of Gab1 and Gab2 Docking Proteins in Interleukin 6-induced Proliferation and Survival of Multiple Myeloma Cells
    Klaus Podar, Gustavo Mostoslavsky, Martin Sattler, Yu‐Tzu Tai, Toshiaki Hayashi, Laurence P. Catley, Teru Hideshima, Richard C. Mulligan, Dharminder Chauhan, Kenneth Carl Anderson · 2004 · Journal of Biological Chemistry
99. HPC1/RNASEL Mediates Apoptosis of Prostate Cancer Cells Treated with 2′,5′-Oligoadenylates, Topoisomerase I Inhibitors, and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand
    Krishnamurthy Malathi, Jayashree M. Paranjape, Ram N Ganapathi, Robert H. Silverman · 2004 · Cancer Research
100. PI3K expression and PIK3CA mutations are related to colorectal cancer metastases
     Yu-Fen Zhu · 2012 · World Journal of Gastroenterology