The specificities of protein kinase inhibitors: an update

Cited by (1,000)

Items 101–200 of 1,000

1. Activation, regulation, and inhibition of DYRK1A
   Walter B. Becker, Wolfgang Sippl · 2010 · FEBS Journal
2. Automated, Quantitative Screening Assay for Antiangiogenic Compounds Using Transgenic Zebrafish
   T. Cameron Tran, Blossom Sneed, Jamil Haider, Delali Blavo, Audrey White, Temitope Aiyejorun, Timothy C. Baranowski, Amy L. Rubinstein, Thanh N. Doan, Raymond J Dingledine et al. · 2007 · Cancer Research
3. Roscovitine in cancer and other diseases.
   Jonas Cicenas, K. Pavan Kalyan, Aleksandras Sorokinas, Edvinas Stankunas, Josh Levy, Ingrida Meskinyte, Vaidotas Stankevičius, Algirdas Kaupinis, Mindaugas Valius · 2015 · Europe PMC (PubMed Central)
4. Global Effects of Kinase Inhibitors on Signaling Networks Revealed by Quantitative Phosphoproteomics
   Cuiping Pan, Jesper Velgaard Olsen, Henrik Daub, Matthias Mann · 2009 · Molecular & Cellular Proteomics
5. Neuroprotection against Focal Ischemic Brain Injury by Inhibition of c-Jun N-Terminal Kinase and Attenuation of the Mitochondrial Apoptosis-Signaling Pathway
   Yanqin Gao, Armando P. Signore, Wei Yin, Guodong Cao, Xiao‐Ming Yin, Feng‐Yan Sun, Yumin Luo, Steven H. Graham, Jun Chen · 2005 · Journal of Cerebral Blood Flow & Metabolism
6. Green Tea Polyphenols Rescue of Brain Defects Induced by Overexpression of DYRK1A
   Fayçal Guedj, Catherine Sebrié, Isabelle Rivals, Aurélie Ledru, Evelyne Paly, Jean C. Bizot, Desmond Smith, Edward M. Rubin, Brigitte Gillet, Maria Lourdes Arbonés et al. · 2009 · PLoS ONE
7. Distinct Priming Kinases Contribute to Differential Regulation of Collapsin Response Mediator Proteins by Glycogen Synthase Kinase-3 in Vivo
   Adam R. Cole, Frédéric Causeret, Gökhan Yadırgı, C. James Hastie, Hilary McLauchlan, Edward J. McManus, Félix Hernández, Britta Johanna Eickholt, Margareta Nikolić, Calum D. Sutherland · 2006 · Journal of Biological Chemistry
8. Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Induces Apoptosis and Cell Cycle Arrest in A549 Cells through p53 Accumulation via c-Jun NH2-Terminal Kinase-Mediated Phosphorylation at Serine 15 in Vitro and in Vivo
   Ya‐Ling Hsu, Chien-Yu Cho, Po‐Lin Kuo, Yu‐Ting Huang, Chun‐Ching Lin · 2006 · Journal of Pharmacology and Experimental Therapeutics
9. Chemical modulation of memory formation in larval zebrafish
   Marc A. Wolman, Roshan A. Jain, Laura Liss, Michael Granato · 2011 · Proceedings of the National Academy of Sciences
10. β1‐Integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases
    Teet Velling, Stina Nilsson, Anne Stefansson, Staffan Johansson · 2004 · EMBO Reports
11. A traffic-activated Golgi-based signalling circuit coordinates the secretory pathway
    Teodoro Pulvirenti, Monica Giannotta, Mariagrazia Capestrano, Mirco Capitani, Antonio Pisanu, Roman Polishchuk, Enrica San Pietro, Galina V. Beznoussenko, Mironov Aa, Gabriele Turacchio et al. · 2008 · Nature Cell Biology
12. Activity‐based kinase profiling of approved tyrosine kinase inhibitors
    Daisuke Kitagawa, Koichi Yokota, Masaki Gouda, Yugo Narumi, Hiroshi Ohmoto, Eiji Nishiwaki, Kensaku Akita, Yasuyuki Kirii · 2012 · Genes to Cells
13. α2-Chimaerin, Cyclin-Dependent Kinase 5/p35, and Its Target Collapsin Response Mediator Protein-2 Are Essential Components in Semaphorin 3A-Induced Growth-Cone Collapse
    Matthew P. Brown, Tom Jacobs, Britta Johanna Eickholt, Giovanna Ferrari, Mabel Teo, Clinton A. L. Monfries, Robert Zhong Qi, Thomas Leung, Louis Lim, Christine Hall · 2004 · Journal of Neuroscience
14. Measuring and interpreting the selectivity of protein kinase inhibitors
    Lynette A. Smyth, Ian Collins · 2009 · Journal of Chemical Biology
15. 4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects
    Vladimı́r Kryštof, Petr Cankař, Iveta Fryšová, Jan Slouka, George A. Kontopidis, Petr Džubák, Marián Hajdúch, Josef Srovnal, Walter Filgueira de Azevedo, M Orság et al. · 2006 · Journal of Medicinal Chemistry
16. DYRK1A, a dosage-sensitive gene involved in neurodevelopmental disorders, is a target for drug development in down syndrome
    Duchon, Arnaud, Herault, Yann · 2016 · Frontiers in Behavioral Neuroscience
17. Mechanisms for Lysophosphatidic Acid-induced Cytokine Production in Ovarian Cancer Cells
    Xianjun Fang, Shuangxing Yu, Robert C. Bast, Shuying Liu, Hong‐Ji Xu, Shi-Xue Hu, Ruth LaPushin, Francois X. Claret, Bharat Bhushan Aggarwal, Yiling Lu et al. · 2004 · Journal of Biological Chemistry
18. Identification of SRC as a key PKA-stimulated tyrosine kinase involved in the capacitation-associated hyperactivation of murine spermatozoa
    Mark A. Baker, Louise Hetherington, R. John Aitken · 2006 · Journal of Cell Science
19. 2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2
    Mario Angelo Pagano, Flavio Meggio, Maria Ruzzene, Mariola Andrzejewska, Zygmunt Kazimierczuk, Lorenzo Alberto Pinna · 2004 · Biochemical and Biophysical Research Communications
20. Optimization of Protein Kinase CK2 Inhibitors Derived from 4,5,6,7-Tetrabromobenzimidazole
    Mario Angelo Pagano, Mariola Andrzejewska, Maria Ruzzene, Stefania Sarno, Luca Cesaro, Jenny Bain, Matthew Elliott, Flavio Meggio, Zygmunt Kazimierczuk, Lorenzo Alberto Pinna · 2004 · Journal of Medicinal Chemistry
21. CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases
    Bettayeb, K, Oumata, N, Echalier, A, Ferandin, Y, Endicott, J A, Galons, H, Meijer, L · 2008 · Oncogene
22. Ethanol Induces Long-Term Facilitation of NR2B-NMDA Receptor Activity in the Dorsal Striatum: Implications for Alcohol Drinking Behavior
    Jun Wang, Sébastien Carnicella, Khanhky Phamluong, Jérôme Jeanblanc, Jennifer A. Ronesi, Nadia Chaudhri, Patricia H. Janak, David M. Lovinger, Dorit Ron A · 2007 · Journal of Neuroscience
23. 1-Azakenpaullone is a selective inhibitor of glycogen synthase kinase-3β
    Conrad Kunick, Kathrin Lauenroth, Maryse Leost, Laurent Meijer, Thomas Lemcke · 2003 · Bioorganic & Medicinal Chemistry Letters
24. Phosphoproteomics in cancer
    Harsha Gowda, Akhilesh Pandey · 2010 · Molecular Oncology
25. The Discovery of Polo-Like Kinase 4 Inhibitors: Identification of (1R,2S)-2-(3-((E)-4-(((cis)-2,6-Dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a Potent, Orally Active Antitumor Agent
    Peter B. Sampson, Yong Liu, Bryan Forrest, Graham R. Cumming, Sze-Wan Li, Narendra Kumar Patel, Louise G. Edwards, Radoslaw S. Laufer, Miklós Fehér, Fuqiang Ban et al. · 2014 · Journal of Medicinal Chemistry
26. PMA Induces the MUC5AC Respiratory Mucin in Human Bronchial Epithelial Cells, via PKC, EGF/TGF-α, Ras/Raf, MEK, ERK and Sp1-dependent Mechanisms
    Christopher A. Hewson, Mark R. Edbrooke, Sebastian Lennox Johnston · 2004 · Journal of Molecular Biology
27. Src protein tyrosine kinase family and acute inflammatory responses
    Daisuke Okutani, Monika Lodyga, Bing Han, Mingyao Liu · 2006 · American Journal of Physiology-Lung Cellular and Molecular Physiology
28. Mitogen‐activated protein kinases in hemostasis and thrombosis
    Frédéric Adam, Alexandre Kauskot, Jean‐Philippe Rosa, Marijke Bryckaert · 2008 · Journal of Thrombosis and Haemostasis
29. DYRK1A and cognition: A lifelong relationship
    Maria Lourdes Arbonés, Aurore Thomazeau, Akiko Nakano-Kobayashi, Masatoshi Hagiwara, Jean Maurice Delabar · 2018 · Pharmacology & Therapeutics
30. High-Efficiency Induction of Neural Conversion in Human ESCs and Human Induced Pluripotent Stem Cells with a Single Chemical Inhibitor of Transforming Growth Factor Beta Superfamily Receptors
    Zhou, Jiaxi, Su, Pei, Li, Dong, Tsang, Stephanie, Duan, Enkui, Wang, Fei · 2010 · Stem Cells
31. The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression
    Sang Kyum Kim, RAYMOND F. NOVAK · 2006 · Pharmacology & Therapeutics
32. Context-specific inhibition of JNKs: overcoming the dilemma of protection and damage
    Vicki Waetzig, Thomas Herdegen · 2005 · Trends in Pharmacological Sciences
33. Physiological Stimuli Induce PAD4-Dependent, ROS-Independent NETosis, With Early and Late Events Controlled by Discrete Signaling Pathways
    Olga Tatsiy, Patrick P. McDonald · 2018 · Frontiers in Immunology
34. A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding
    Marie A. Bogoyevitch, David P. Fairlie · 2007 · Drug Discovery Today
35. Cyclin-dependent kinase inhibitors
    Yun Dai · 2003 · Current Opinion in Pharmacology
36. Assessment of Chemical Coverage of Kinome Space and Its Implications for Kinase Drug Discovery
    Paul Bamborough, David Harold Drewry, Gavin Harper, Gary K. Smith, Klaus Schneider · 2008 · Journal of Medicinal Chemistry
37. Molecular connexions between dementia and diabetes
    Adam R. Cole, Arlene J. Astell, Charlotte Green, Calum D. Sutherland · 2007 · Neuroscience & Biobehavioral Reviews
38. The Fibroblast Growth Factor Receptor Inhibitor PD173074 Blocks Small Cell Lung Cancer Growth In vitro and In vivo
    Olivier E. Pardo, John R. Latigo, Rosemary E. Jeffery, Emma L. Nye, Richard Poulsom, Bradley Spencer‐Dene, Nicholas Robert Lemoine, Gordon Stamp, Eric Ofori Aboagye, Michael J. Seckl · 2009 · Cancer Research
39. DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome
    Claudia Canzonetta, Claire Mulligan, Samuel Deutsch, Sandra Ruf, Aideen O’Doherty, Robert Lyle, Christelle Borel, Nathalie Lin-Marq, Frédéric Delom, Jürgen Groet et al. · 2008 · The American Journal of Human Genetics
40. Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities
    Rueda, Noemí, Flórez, Jesús, Martínez-Cué, Carmen · 2012 · Neural Plasticity
41. DYRK1A in neurodegeneration and cancer: Molecular basis and clinical implications
    Ramzi H. Abbassi, Terrance G. Johns, Michael Kassiou, Lenka Munoz · 2015 · Pharmacology & Therapeutics
42. Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells
    Amy M Mingo-Sion, Peter M. Marietta, Erich Koller, Douglas M. Wolf, Carla L. Van Den Berg · 2004 · Oncogene
43. Essential Role for Mitogen-activated Protein (MAP) Kinase Phosphatase-1 in Stress-responsive MAP Kinase and Cell Survival Signaling
    J. Julie Wu, Anton M. Bennett · 2005 · Journal of Biological Chemistry
44. The Stability of Tristetraprolin mRNA Is Regulated by Mitogen-activated Protein Kinase p38 and by Tristetraprolin Itself
    Carmen R. Tchen, Matthew Brook, Jeremy Saklatvala, Andrew R. Clark · 2004 · Journal of Biological Chemistry
45. Src-Family Kinases Are Activated in Non-Small Cell Lung Cancer and Promote the Survival of Epidermal Growth Factor Receptor-Dependent Cell Lines
    Jie Zhang, Shailaja Kalyankrishna, Marie Wislez, Nishan Thilaganathan, Babita Saigal, Wei Wei, Long Ma, Ignacio Ivan Wistuba, Faye M. Johnson, Jonathan M. Kurie · 2007 · American Journal Of Pathology
46. Engulfment of Apoptotic Cells Is Negatively Regulated by Rho-mediated Signaling
    Annie‐Carole Tosello‐Trampont, Kumiko Nakada‐Tsukui, Kodi S. Ravichandran · 2003 · Journal of Biological Chemistry
47. Adaptive Cellular Stress Pathways as Therapeutic Targets of Dietary Phytochemicals: Focus on the Nervous System
    Jaewon Lee, Dong‐Gyu Jo, Daeui Park, Hae Young Chung, Mark P. Mattson · 2014 · Pharmacological Reviews
48. Protein kinase inhibition of clinically important staurosporine analogues
    Osman A. B. S. M. Gani, Richard Alan Engh · 2010 · Natural Product Reports
49. Role of the JNK Pathway in Human Diseases
    Kanaga Sabapathy · 2012 · Progress in molecular biology and translational science
50. Obligatory Role of Src Kinase in the Signaling Mechanism for TRPC3 Cation Channels
    Guillermo Vázquez, Barbara J. Wedel, Brian T. Kawasaki, Gary St. J. Bird, James W. Putney · 2004 · Journal of Biological Chemistry
51. Recent Advances in the Design, Synthesis, and Biological Evaluation of Selective DYRK1A Inhibitors: A New Avenue for a Disease Modifying Treatment of Alzheimer’s?
    Breland E. Smith, Federico Medda, Vijay M. Gokhale, Travis L. Dunckley, Christopher Hulme · 2012 · ACS Chemical Neuroscience
52. Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia
    Nikki L. Jernigan, Benjimen R. Walker, Thomas C. Resta · 2008 · American Journal of Physiology-Lung Cellular and Molecular Physiology
53. Mixed-Lineage Kinases: A Target for the Prevention of Neurodegeneration
    Leo H. Wang, Cagri G. Besirli, Eugene M. Johnson · 2004 · The Annual Review of Pharmacology and Toxicology
54. Epigallocatechin-3-gallate prevents oxidative phosphorylation deficit and promotes mitochondrial biogenesis in human cells from subjects with Down's syndrome
    Daniela Valenti, Domenico De Rasmo, Anna Signorile, Leonardo Rossi, Lidia de BARI, Iris Scala, Barbara Granese, Sergio Papa, Rosa Anna Vacca · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
55. Inhibition of Cell Proliferation and Cell Cycle Progression by Specific Inhibition of Basal JNK Activity
    Lihua Du, Christopher S. Lyle, Toria B. Obey, William A. Gaarde, Jeffrey A. Muir, Brydon L. Bennett, Timothy C. Chambers · 2004 · Journal of Biological Chemistry
56. Characterization of a Conserved Structural Determinant Controlling Protein Kinase Sensitivity to Selective Inhibitors
    Stephanie Blencke, Birgit Zech, Ola Engkvist, Zoltán Greff, László Őrfi, Zoltán Horváth, Gÿorgý Kéri, Axel Ullrich, Henrik Daub · 2004 · Chemistry & Biology
57. Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt
    Y-H Han, X Cao, Bingzhen Lin, F Lin, Siva K. Kolluri, John L. Stebbins, John C. Reed, Marcia I. Dawson, X-k Zhang · 2006 · Oncogene
58. A Framework for the Establishment of a Cnidarian Gene Regulatory Network for “Endomesoderm” Specification: The Inputs of ß-Catenin/TCF Signaling
    Röttinger, Eric, Dahlin, Paul, Martindale, Mark Q. · 2012 · PLoS Genetics
59. Ubiquitin-Specific Proteases (USPs) and Metabolic Disorders
    Hiroshi Kitamura · 2023 · International Journal of Molecular Sciences
60. GSK-3β inhibition/β-catenin stabilization in ventral midbrain precursors increases differentiation into dopamine neurons
    Gonçalo Castelo‐Branco, Nina Rawal, Ernest Arenas · 2004 · Journal of Cell Science
61. Targeting transforming growth factor (TGF)‐βRI inhibits activation of β1 integrin and blocks vascular invasion in hepatocellular carcinoma†
    Emilia Fransvea, Antonio Mazzocca, Salvatore Antonaci, Gianluigi Giannelli · 2008 · Hepatology
62. Synthesis and Target Identification of Hymenialdisine Analogs
    Yongqin Wan, Wooyoung Hur, Charles Y. Cho, Yi Liu, Francisco J. Adrian, Olivier Lozach, Stéphane Bach, Thomas Mayer, Doriano Fabbro, Laurent Meijer et al. · 2004 · Chemistry & Biology
63. Roscovitine-Derived, Dual-Specificity Inhibitors of Cyclin-Dependent Kinases and Casein Kinases 1
    Oumata, Nassima, Bettayeb, Karima, Ferandin, Yoan, Demange, Luc, Lopez-Giral, Angela, Goddard, Marie-Lorène, Myrianthopoulos, Vassilios, Mikros, Emmanuel, Flajolet, Marc, Greengard, Paul et al. · 2008 · Journal of Medicinal Chemistry
64. Polyphenols and neuroprotection: therapeutic implications for cognitive decline
    Caruso, Giuseppe, Torrisi, Sebastiano A., Mogavero, Maria Paola, Currenti, Walter, Castellano, Sabrina, Godos, Justyna, Ferri, Raffaele, Galvano, Fabio, Leggio, Gian Marco, Grosso, Giuseppe et al. · 2022 · Pharmacology & Therapeutics
65. RETRACTED: Kinase inhibitors and airway inflammation
    Ian Michael Adcock, Kian Fan Chung, Gaetano Caramori, Kazuhiro Ito · 2006 · European Journal of Pharmacology · Retracted
66. Distinct Mechanisms of Clathrin-independent Endocytosis Have Unique Sphingolipid Requirements
    Zhi-jie Jey Cheng, Raman Deep Singh, Deepak Sharma, Eileen L. Holicky, Kentaro Hanada, David L. Marks, Richard E. Pagano · 2006 · Molecular Biology of the Cell
67. An Apoptotic Signaling Pathway in the Interferon Antiviral Response Mediated by RNase L and c-Jun NH2-terminal Kinase
    Geqiang Li, Ying Xiang, Kanaga Sabapathy, Robert H. Silverman · 2004 · Journal of Biological Chemistry
68. Transient expression of <i>Mnb/Dyrk1a</i> couples cell cycle exit and differentiation of neuronal precursors by inducing <i>p27KIP1</i> expression and suppressing NOTCH signaling
    Hämmerle, Barbara, Ulin, Edgar, Guimera, Jordi, Becker, Walter, Guillemot, François, Tejedor, Francisco J. · 2011 · Development
69. Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics
    Dnyandev B. Jarhad, Karishma K. Mashelkar, Hong‐Rae Kim, Minsoo Noh, Lak Shin Jeong · 2018 · Journal of Medicinal Chemistry
70. Human intrahepatic biliary epithelial cells function in innate immunity by producing IL‐6 and IL‐8 via the TLR4‐NF‐κB and ‐MAPK signaling pathways
    Terufumi Yokoyama, Atsumasa Komori, Minoru Nakamura, Yasushi Takii, Takashi Kamihira, Shinji Shimoda, Tsuyoshi Mori, Shinsuke Fujiwara, Makiko Koyabu, Ken Taniguchi et al. · 2006 · Liver International
71. Prothoracicotropic Hormone
    Robert Rybczynski · 2005 · Elsevier eBooks
72. Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway
    Natalia V. Oleinik, Natalia I. Krupenko, Sergey A. Krupenko · 2007 · Oncogene
73. Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38δ at Thr50 promotes microtubule assembly
    Feijoo, Carmen, Campbell, David G., Jakes, Ross, Goedert, Michel, Cuenda, Ana · 2005 · Journal of Cell Science
74. DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine
    Anne Seifert, Lindsey A. Allan, Paul R. Clarke · 2008 · FEBS Journal
75. Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo
    Jing Lü, Jun-Ye MIAO, Tao Su, Ying Liu, Rongqiao He · 2013 · Biochimica et Biophysica Acta (BBA) - General Subjects
76. A small-molecule approach to studying invasive mechanisms of Toxoplasma gondii
    Kimberly L. Carey, Nicholas James Westwood, Timothy John Mitchison, Gary E. Ward · 2004 · Proceedings of the National Academy of Sciences
77. Ribotoxic Stress Response to the Trichothecene Deoxynivalenol in the Macrophage Involves the Src Family Kinase Hck
    Hui-Ren Zhou, Qunshan Jia, James J. Pestka · 2005 · Toxicological Sciences
78. High‐Throughput Screening for Kinase Inhibitors
    Oliver von Ahsen, Ulf Bömer · 2005 · ChemBioChem
79. c-Jun N-Terminal Kinases (JNKs) in Myocardial and Cerebral Ischemia/Reperfusion Injury
    Maria Shvedova, Yana Anfinogenova, Elena N. Atochina‐Vasserman, Igor A. Schepetkin, Dmitriy N. Atochin · 2018 · Frontiers in Pharmacology
80. 6-(Methylsulfinyl)hexyl isothiocyanate suppresses inducible nitric oxide synthase expression through the inhibition of Janus kinase 2-mediated JNK pathway in lipopolysaccharide-activated murine macrophages
    Takuhiro Uto, Makoto Fujii, De‐Xing Hou · 2005 · Biochemical Pharmacology
81. PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells
    Yutaro Obara, Kirstin Labudda, Tara J. Dillon, Philip A. Stork · 2004 · Journal of Cell Science
82. Inhibitors of c-Jun N-terminal kinases—JuNK no more?
    Marie A. Bogoyevitch, Peter G. Arthur · 2007 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
83. Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium
    Sevag Kaladchibachi, Bradley W. Doble, Norman Anthopoulos, James Robert Woodgett, Armen S. Manoukian · 2007 · Journal of Circadian Rhythms
84. Targeting JNK3 for the treatment of neurodegenerative disorders
    Lynn Resnick, Myles Fennell · 2004 · Drug Discovery Today
85. Staphylococcus aureus Biofilm and Planktonic cultures differentially impact gene expression, mapk phosphorylation, and cytokine production in human keratinocytes
    Patrick R. Secor, Garth A. James, Philip H. Fleckman, John E. Olerud, Kate McInnerney, Philip S. Stewart · 2011 · BMC Microbiology
86. Inhibitors of Protein Kinase Signaling Pathways
    Thomas L. Force, Keisuke Kuida, Mark Namchuk, Keykavous Parang, John M. Kyriakis · 2004 · Circulation
87. Modulation of Prosurvival Signaling in Fibroblasts by a Protein Kinase Inhibitor Protects against Fibrotic Tissue Injury
    Ragini Vittal, Jeffrey Craig Horowitz, Bethany B. Moore, Hengmin Zhang, Fernando J. Martínez, Galen B. Toews, Theodore J. Standiford, Victor John Thannickal · 2005 · American Journal Of Pathology
88. The Tubulin-Binding Agent Combretastatin A-4-Phosphate Arrests Endothelial Cells in Mitosis and Induces Mitotic Cell Death
    Chryso Kanthou, Olga Greco, Anna L. Stratford, Ian O. Cook, Richard A. Knight, Omar Benzakour, Gillian M. Tozer · 2004 · American Journal Of Pathology
89. A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery
    Yinghong Gao, Stephen P. Davies, Martin A. Augustin, Anna M. Woodward, Umesh A. Patel, Robert Kovelman, Kevin J. Harvey · 2013 · Biochemical Journal
90. Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium
    William S. Marshall, Carlo Gunnar Ossum, Else Kay Hoffmann · 2005 · Journal of Experimental Biology
91. Europium Tetracycline as a Luminescent Probe for Nucleoside Phosphates and Its Application to the Determination of Kinase Activity
    Michael Schäferling, Otto S. Wolfbeis · 2007 · Chemistry - A European Journal
92. Tetrabromocinnamic Acid (TBCA) and Related Compounds Represent a New Class of Specific Protein Kinase CK2 Inhibitors
    Mario Angelo Pagano, Giorgia Poletto, Giovanni Di Maira, Giorgio Cozza, Maria Ruzzene, Stefania Sarno, Jenny Bain, Matthew Elliott, Stefano Moro, Giuseppe Zagotto et al. · 2006 · ChemBioChem
93. c-Jun N-Terminal Kinases Mediate Reactivation of Akt and Cardiomyocyte Survival After Hypoxic Injury In Vitro and In Vivo
    Zhili Shao, Kausik Bhattacharya, Eileen Hsich, Larry Park, Brian M. Walters, Ursula A. Germann, Yow‐Ming Wang, John M. Kyriakis, Ramon W. Mohanlal, Keisuke Kuida et al. · 2005 · Circulation Research
94. Phosphorylation of the enteropathogenic E. coli receptor by the Src-family kinase c-Fyn triggers actin pedestal formation
    N. Phillips, Richard D. Hayward, V. Koronakis · 2004 · Nature Cell Biology
95. Design and Synthesis of the First Generation of Novel Potent, Selective, and in Vivo Active (Benzothiazol-2-yl)acetonitrile Inhibitors of the c-Jun N-Terminal Kinase
    Pascale Gaillard, Isabelle Jeanclaude-Etter, Vittoria Ardissone, Steve Arkinstall, Yves Cambet, Montserrat Camps, Christian Chabert, Dennis J. Church, Rocco Cirillo, Denise Gretener et al. · 2005 · Journal of Medicinal Chemistry
96. Harmine is an ATP-competitive inhibitor for dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A)
    Tatyana Adayev, Jerzy Węgiel, Yu‐Wen Hwang · 2010 · Archives of Biochemistry and Biophysics
97. Understanding Kinase Selectivity Through Energetic Analysis of Binding Site Waters
    Daniel D. Robinson, Woody Sherman, Ramy Farid · 2010 · ChemMedChem
98. Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells
    Ines N. Hahntow, Folker Schneller, Madlene Oelsner, K Weick, Ingo Ringshausen, Falko Fend, Christian Peschel, Thomas W. Decker · 2004 · Leukemia
99. NF-κB RelA opposes epidermal proliferation driven by TNFR1 and JNK
    Jennifer Y. Zhang, Cheryl L. Green, Shiying Tao, Paul A. Khavari · 2004 · Genes & Development
100. Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinases (DYRKs) and cdc2-Like Kinases (CLKs) in Human Disease, an Overview
     Mattias F. Lindberg, Laurent Meijer · 2021 · International Journal of Molecular Sciences