NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation

Serrander, Lena, Cartier, Laetitia, Bedard, Karen, Banfi, Botond, Lardy, Bernard, Plastre, Olivier, Sienkiewicz, Andrzej, Fórró, Lászlo, Schlegel, Werner, Krause, Karl-Heinz·2007·Biochemical Journal

DOI 10.1042/bj20061903

Cited by (632)

Items 501–600 of 632

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Kirti Singh, Razan L. Teyani, Nader H. Moniri · 2023 · Biomedicine & Pharmacotherapy
Autophagy, Oxidative Stress, and Redox Regulation
Jipeng Ma, Lifang Yang, Jun Tao Ren, Jian Zhi Yang · 2018 · Elsevier eBooks
Grape pomace extract, rich in phenolic compounds, attenuates obesity-induced nephropathy by modulating energy metabolism dysregulation and oxidative stress in mice fed a high-fat diet
Tatiana Figueras, Diahann J. Perdicaro, Valeria E. Cacciamani, Andrea Fernanda Gil Lorenzo, Laila Suhaiman, Andrea Antoniolli, Marcela A. Vazquez Prieto, Valeria Victoria Costantino · 2025 · Food & Function
The selective NOX4 inhibitor GLX7013159 decreases blood glucose concentrations and human beta-cell apoptotic rates in diabetic NMRI nu/nu mice transplanted with human islets
Andris Elksnis, Nils Welsh, Per Wikström, Joey Lau, Per‐Ola Carlsson · 2023 · Free Radical Research
The Evolving Concept of Oxidative Stress
Denise de Castro Fernandes, Diego Bonatto, Francisco Rafael Martins Laurindo · 2010 · Humana Press eBooks
Skeletal muscle Nox4 knockout prevents and Nox2 knockout blunts loss of maximal diaphragm force in mice with heart failure with reduced ejection fraction
Ravi A. Kumar, Dongwoo Hahn, Rachel Catherine Kelley, Derek R. Muscato, Alex Shamoun, Nuria Curbelo-Bermudez, W. Greyson Butler, Svetlana Yegorova, TERENCE EDWARD RYAN, Leonardo F. Ferreira · 2022 · Free Radical Biology and Medicine
Development of a No-Wash Assay for Mitochondrial Membrane Potential Using the Styryl Dye DASPEI
Kristian H. R. Jensen, Jens C. Rekling · 2010 · SLAS DISCOVERY
Cardiac function and tolerance to ischemia–reperfusion injury in chronic kidney disease
James Matthew Kuczmarski, Christopher R. Martens, Shannon Liduina Lennon, David G. Edwards · 2013 · Nephrology Dialysis Transplantation
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Role of Nox4 in Neuronal Differentiation of Mouse Subventricular Zone Neural Stem Cells
Ki-Youb Park, Yerin Na, Man Su Kim · 2016 · Journal of Life Science
Lithocholic acid: a new emergent protector of intestinal calcium absorption under oxidant conditions
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High‐salt diet contributes to excess oxidative stress and abnormal metabolism in mouse ovaries
Entai Hou, Jie Yan, Xiaohui Zhu, Jie Qiao · 2022 · Biomedical Chromatography
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Adrita Banerjee, Tiyasa Dey, Arnab Kumar Ghosh, Sanatan Mishra, Debasish Bandyopadhyay, Aindrila Chattopadhyay · 2020 · Toxicology Reports
Nox4 Maintains Blood Pressure during Low Sodium Diet
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Estêvão Bassi, Marcel Liberman, Marina Kamla Martinatti, Luiz Aparecido Bortolotto, Francisco Rafael Martins Laurindo · 2014 · Brazilian Journal of Medical and Biological Research
Nitric oxide and related factors linked to oxidation and inflammation as possible biomarkers of heart failure
Roberto Jorge Bonafede, Walter A. Manucha · 2018 · Clínica e Investigación en Arteriosclerosis (English Edition)
Characterization of signaling mechanisms regulating cardiac contractility
Anna‐Maria Kubin · 2011
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Rebecca Seitz, Martina A. Müller, Karsten Gülow · 2026 · Antioxidants
Role of Mitochondrial ROS for Calcium Alternans in Atrial Myocytes
Yuriana Oropeza‐Almazán, Lothar A. Blatter · 2024 · Biomolecules
Prolactin protects hippocampal neurons against H2O2-induced neurotoxicity by suppressing BAX and NOX4 via the NF-κB signaling pathway
Fernando Macías, Miriam Ulloa, Carmen Clapp, Gonzalo Martı́nez de la Escalera, Edith Arnold · 2024 · PLoS ONE
Oxidative stress-mediated bimodal regulation of polymorphonuclear leukocyte spreading by polyphenolic compounds
Kingo Suzuki, Soichiro Kori, Manatsu Morikawa, Ai Takagi, Hideo Namiki · 2010 · International Immunopharmacology
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Aicha Bouraoui, Ruy A. N. Louzada, Sana Zineb Aimeur, Jehan Waeytens, Frank Wien, Pham My‐Chan Dang, Tania Bizouarn, Corinne Dupuy, Laura Baciou · 2023 · Free Radical Biology and Medicine
An oxide transport chain essential for balanced insulin action
Xiangdong Wu, Keyang Chen, Kevin Jon Williams · 2020 · Atherosclerosis
Role of mitochondria in the differential action of sodium deoxycholate and ursodeoxycholic acid on rat duodenum
Adriana Pérez, María A. Rivoira, Valeria Andrea Rodríguez, Ana Maria Estivalete Marchionatti, Nori Tolosa de Talamoni · 2020 · Canadian Journal of Physiology and Pharmacology
Physiological interrelationships between NADPH oxidases and chromatin remodelling
Alison C. Brewer · 2021 · Free Radical Biology and Medicine
Aging‐Associated Nox4 ‐Mediated Mitochondrial Reactive Oxygen Species and DNA Damage Promote Vascular Cell Reprogramming and Aortic Remodeling in Abdominal Aneurysms
Aleksandr E. Vendrov, Jamille Silveira Fernandes Chamon, Julia Levin, Takayuki Hayami, Chaitanya Madamanchi, Morgan Salmon, Nageswara R. Madamanchi · 2026 · Journal of the American Heart Association
GKT137831 and hydrogen peroxide increase the release of 6-nitrodopamine from the human umbilical artery, rat-isolated right atrium, and rat-isolated vas deferens
José Britto‐Júnior, Rafael Furlaneto, Antonio Tiago Lima, Mariana G. de Oliveira, Beatrice Severino, Francesco Frecentese, Ferdinando Fiorino, Giuseppe Caliendo, Marcelo Nicolás Muscará, Gilberto De Nucci · 2024 · Frontiers in Pharmacology
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Pankaj Neje, Brijesh Gulabrao Taksande, Milind Janrao Umekar, Shubhada V Mangrulkar · 2024 · Microgravity Science and Technology
Bone Adaptations to a Whole Body Vibration Protocol in Murine Models of Different Ages: A Preliminary Study on Structural Changes and Biomarker Evaluation
Ida Cariati, Roberto Bonanni, Cristian Romagnoli, Lucio Caprioli, Giovanna D’Arcangelo, Virginia Tancredi, Giuseppe Annino · 2025 · Journal of Functional Morphology and Kinesiology
Integrated Analysis of Metabolites and Biological Endpoints Bring New Insights into Sulfamethoxazole Stress Tolerance in Ryegrass
Yong Yang, Jiangtao Jia, Tao Han, Heng Zhang, Yvjie Wang, Luying Shao, Xinyi Wang · 2025 · Plants
Discovery of Neuroprotective Antioxidants for the Management of Ischemic Brain Stroke
Anil Kumar, Varun Gupta, Aakriti · 2017 · Elsevier eBooks
Rapid fluorescent visualization of multiple NAD(P)H oxidoreductases in homogenate, permeabilized cells, and tissue slices
Anna B. Nikiforova, Р. С. Фадеев, Alexey G. Kruglov · 2013 · Analytical Biochemistry
NAD(P)H oxidase isoforms as therapeutic targets for diabetic complications
Stephen P. Gray, Jay C. Jha, Elyse Di Marco, Karin Agnes Maria Jandeleit-Dahm · 2014 · Expert Review of Endocrinology & Metabolism
Glucose-Induced Expression of DAPIT in Pancreatic β-Cells
Alberto Leguina‐Ruzzi, Anežka Vodičková, Blanka Holendová, Vojtěch Pavluch, Jan A. Tauber, Hana Engstová, Andrea Dlasková, Petr Ježek · 2020 · Biomolecules
Melatonin Enhances Anti-tumoral Effects of Menadione on Colon Cancer Cells
Alejandro Collin, Romina Kohan, Nori Tolosa de Talamoni, Gabriela Picotto · 2021 · Anti-Cancer Agents in Medicinal Chemistry
Detection of hydrogen peroxide by lactoperoxidase-mediated dityrosine formation
Ágnes Donkó, Anna Orient, Pál Tamás Szabó, Gábor Németh, Tibor Vántus, Gÿorgý Kéri, László Őrfi, László Hunyady, László Buday, Miklós Geiszt · 2009 · Free Radical Research
Feasibility exploration of GSH in the treatment of acute hepatic encephalopathy from the aspects of pharmacokinetics, pharmacodynamics, and mechanism
Kangrui Hu, Yexin Xu, Jiye Fan, Huafang Liu, Chanjuan Di, Feng Xu, Linlin Wu, Ke Ding, Tingting Zhang, Leyi Wang et al. · 2024 · Frontiers in Pharmacology
NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy
Mirella El Khoury, Olivier Biondi, Gaëlle Bruneteau, Delphine Sapaly, Sabrina Bendris, Cynthia Bézier, Zoé Clerc, Elias Abi Akar, Laure Weill, Assaad Antoine Eid et al. · 2023 · Frontiers in Cellular Neuroscience
Gut-derived wild blueberry phenolic acid metabolites modulate extrinsic cutaneous damage
John Ivarsson, Abby E. Bennett, Francesca Ferrara, Renee C. Strauch, Andrea Vallese, Massimo Iorizzo, Alessandra Pecorelli, Mary Ann Lila, Giuseppe Valacchi · 2024 · Food & Function
Hypoxia and Hypoxia‐Reoxygenation Potentiate Helicobacter pylori Infection and Gastric Epithelial Cell Proliferation
Indrajit Poirah, Soumyadeep Chakraborty, Pratyush Kumar Padhan, Ashish Kumar Mishra, Debashish Chakraborty, Pragyesh Dixit, Supriya Samal, Niranjan Rout, Shivaram Prasad Singh, Gautam Nath et al. · 2025 · Cancer Medicine
Role of NADPH Oxidase in Beta Cell Dysfunction
Jessica R. Weaver, David Taylor · 2014 · Springer eBooks
Antioxidant Defense Capacity Is Reduced in Thyroid Stem/Precursor Cells Compared to Differentiated Thyrocytes
Fiorenza Gianì, Fabio Allia, Maria Antonietta Trovato, Roberta Masto, Gabriella Pellegriti, Riccardo Vigneri · 2023 · International Journal of Molecular Sciences
QMR® and Patient Blood-Derived Secretome Modulate RPE microRNA Networks Under Oxidative Stress
Simona Alibrandi, Domenico Mordà, Concetta Scimone, Angela D’Ascola, Federica Aliquò, Alessandro Pozzato, Sergio Zaccaria Scalinci, Rosalia D’Angelo, Antonina Sidoti, Luigi Donato · 2025 · International Journal of Molecular Sciences
Teneligliptin and empagliflozin attenuate ferroptosis-mediated acute tubular injury
Chiemi Ema, Takamasa Iwakura, Takayuki Tsuji, Yukihiro Nakayama, Miyu Tsuchida, Atsushi Kitamura, Naoko Katahashi, Sayaka Ishigaki, Shinsuke Isobe, Tomoyuki Fujikura et al. · 2025 · Nephrology Dialysis Transplantation
A Reappraisal of the Utility of L-012 to Measure Superoxide from Biologically Relevant Sources
Stephen B. Haigh, Zachary L. Brown, Mitch Shivers, Hunter G. Sellers, Madison A. West, Scott A. Barman, David W. Stepp, Gábor Csányi, David J. Fulton · 2023 · Antioxidants
Comprehensive Analysis of Metabolites and Biological Endpoints Providing New Insights into the Tolerance of Wheat Under Sulfamethoxazole Stress
Yong Yang, Jiangtao Jia, Tao Han, Heng Zhang, Yvjie Wang, Luying Shao, Xinyi Wang · 2025 · International Journal of Molecular Sciences
Porphyromonas gingivalis Promotes Neuroinflammation by Microglial Ferroptosis via NOX4/PPAR-α/PGC-1α Pathway
Xue Li, Zhenhuan Wu, Chao Hua Yao, Pengye Zhang, Qingyu Zhu, Shunxue Nan, Lei Xiao, Shengcai Qi · 2026 · Research
Reactive oxygen species (ROS) in cancer: from redox signaling and metabolic plasticity to therapeutic vulnerabilities
Taslim Uddin, Tajmin Khanam, Afia Asma, Dr-Mayesha Tasnim, Sultana Tanbin, Aruba Nafisa Parvez, Mohammad Hasan, Anika Zaheen, Anika Tabassum Aziz, Anupama Joy et al. · 2026 · Exploration of Targeted Anti-tumor Therapy
Role of NADPH Oxidase in β Cell Dysfunction
Jessica R. Weaver, David Taylor · 2014 · Springer eBooks
Knockdown of ANGPTL2 promotes left ventricular systolic dysfunction by upregulation of NOX4 in mice
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UV–Vis Absorption and Chemiluminescence Techniques
Frederick A. Villamena · 2016 · Elsevier eBooks
High Glucose-induced ROS Production is Mediated by c-Src in Mesangial Cells
Ken Wing Kin Lee · 2012 · TSpace (University of Toronto)
Lithium-containing 45S5 Bioglass-derived glass-ceramics have antioxidant activity and induce new bone formation in a rat preclinical model of type 1 diabetes mellitus
Fátima Gomez-Gramajo, María A. Rivoira, Valeria Andrea Rodríguez, Gabriela E. Vargas, Rosa Vera Mesones, Maria Paola Zago, Aldo Roberto Boccaccini, Alejandro A. Gorustovich · 2024 · Biomedical Materials
The role of aldosterone on the endothelial dysfunction induced by female hormone deficiency
Wena Dantas Marcarini, Vinícius Bermond Marques, Ariane Calazans Teixeira, Nathanne Santos Ferreira, Dieli Oliveira Nunes, Anna Karolina Nascimento Costa, KATYANA KALINE SILVA FERREIRA, Rita C. Tostes, Eduardo Hertel Ribeiro, Alessandra Simão Padilha et al. · 2025 · Molecular and Cellular Endocrinology
Possible role of the mitochondrial pyruvate dehydrogenase in ketorolac mediated onset and progression of gastric ulcers in male Wistar rats: Protection by melatonin
Romit Majumder, Madhuri Datta, Adrita Banerjee, Trina Roy, Arun Bandyopadhyay, Debasish Bandyopadhyay, Aindrila Chattopadhyay · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Transient Increase in Cardiomyocyte Protein O‐GlcNAcylation Enhances Susceptibility to Pressure Overload‐Induced Cardiac Remodeling
Samuel F. Chang, Chae‐Myeong Ha, Manoja Kumar Brahma, Luke Potter, Mahima S. Reddy, Sayan Bakshi, Kerstin Preuß, Md Saimoon Rahman, Johannes K. Fischer, Caitlin A. Harrell et al. · 2026 · Journal of the American Heart Association
The hepatitis B virus X protein induced fibrosis in Huh7 cells
Moa Son, Sanggyu Park, Moonjae Cho · 2016 · Journal of Applied Biological Chemistry
The Role of NADPH Oxidase in ROS Mediated Differentiation
Benjamin J. Dickson · 2016 · Scholarship@Western (Western University)
Reactive oxygen species-induced reactive oxygen species release in vascular signaling and disease
Young-Mee Kim, Masuko Ushio‐Fukai · 2021 · Elsevier eBooks
Oxidative Stress Enzyme NOX1 Is a New and Important Biomarker for Childhood Appendicitis?
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Nox4: From Discovery to Pathophysiology
Louise Hecker, Kosuke Kato, Kathy K. Griendling · 2023 · Springer eBooks
Melatonin protects against chromium induced oxidative stress-mediated changes in energy metabolism of rat hepatic, cardiac and renal tissues
Priyanka Ghosh, Madhuri Datta, Romit Majumder, Aindrila Chattopadhyay, Debasish Bandyopadhyay · 2024 · Advances in Redox Research
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INHIBITION OF NADPH OXIDASE ACTIVITY AUGMENTS 5-FLUOROURACIL MEDIATED CELL DEATH IN HUMAN COLON CARCINOMA HCT-116 CELLS
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Aspects of Nox/Duox Signaling
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The role and regulatory mechanisms of Nox1 in vascular systems
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