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HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

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A conserved family of prolyl-4-hydroxylases that modify HIF

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Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

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Cellular and developmental control of O 2 homeostasis by hypoxia-inducible factor 1α

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The Acute Phase of Experimental Cardiogenic Shock Is Counteracted by Microcirculatory and Mitochondrial Adaptations

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Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens

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Comparative Effects of Coenzyme Q10 or n-3 Polyunsaturated Fatty Acid Supplementation on Retinal Angiogenesis in a Rat Model of Oxygen-Induced Retinopathy

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Impact of Hypoxia over Human Viral Infections and Key Cellular Processes

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HIF-2α Expression Is Suppressed in SCLC Cells, Which Survive in Moderate and Severe Hypoxia When HIF-1α Is Repressed

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Short-term hypoxic vasodilationin vivois mediated by bioactive nitric oxide metabolites, rather than free nitric oxide derived from haemoglobin-mediated nitrite reduction

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Fetal Programming and Sexual Dimorphism of Mitochondrial Protein Expression and Activity of Hearts of Prenatally Hypoxic Guinea Pig Offspring

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Glucose plays a main role in human fibroblasts adaptation to hypoxia

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Ammonia mediates mitochondrial uncoupling and promotes glycolysis via HIF-1 activation in human breast cancer MDA-MB-231 cells

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Mitochondrial Signaling in Hypoxia

Lukyanova, L. D. (2013) · Open Journal of Endocrine and Metabolic Diseases · doi:10.4236/ojemd.2013.32a004 · Cited by 22

Cellular Respiration and Carcinogenesis

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HIF-1α and periodontitis: Novel insights linking host-environment interplay to periodontal phenotypes

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Moderate Hypoxia Down-Regulates Interleukin-6 Secretion and TLR4 Expression in Human Sw.71 Placental Cells

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SUMO, hypoxia and the regulation of metabolism

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Gas regulation of complex II reversal via electron shunting to fumarate in the mammalian ETC

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Association of hypoxia inducible factor 1-Alpha gene polymorphisms with multiple disease risks: A comprehensive meta-analysis

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HIF-1α regulates osteoclastogenesis and alveolar bone resorption in periodontitis via ANGPTL4

Qi, X., Bie, M., Jiang, R., & Kang, F. (2023) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2023.105736 · Cited by 19

USP11 promotes glycolysis by regulating HIF ‐1α stability in hepatocellular carcinoma

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Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation

Sontakke, P., Koczula, K. M., Jaques, J., Wierenga, A. T. J., Brouwers-Vos, A. Z., Pruis, M. G. M., Günther, U. L., Vellenga, E., & Schuringa, J. J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0153226 · Cited by 19

Aglycemic HepG2 Cells Switch From Aminotransferase Glutaminolytic Pathway of Pyruvate Utilization to Complete Krebs Cycle at Hypoxia

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Hypoxia enhances blood O2 affinity and depresses skeletal muscle O2 consumption in zebrafish (Danio rerio)

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Is nuclear sirtuin SIRT6 a master regulator of immune function?

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Dual-Mode Tumor Imaging Using Probes That Are Responsive to Hypoxia-Induced Pathological Conditions

Subasinghe, S. A. A. S., Pautler, R. G., Samee, M. A. H., Yustein, J. T., & Allen, M. J. (2022) · Biosensors · doi:10.3390/bios12070478 · Cited by 18

Oxygen recovery up-regulates avian UCP and ANT in newly hatched ducklings

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Functional roles of globin proteins in hypoxia-tolerant ectothermic vertebrates

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Nitric oxide is a versatile sensor of low oxygen stress in plants

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Sirtuin 6 attenuates periapical lesion propagation by modulating hypoxia‐induced chemokine (C‐C motif) ligand 2 production in osteoblasts

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Comparative genomics of cetartiodactyla: energy metabolism underpins the transition to an aquatic lifestyle

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High expression of arachidonate 15-lipoxygenase and proinflammatory markers in human ischemic heart tissue

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Shotgun analysis to identify differences in protein expression between granulocytes and hyalinocytes of the European flat oyster Ostrea edulis

de la Ballina, N. R., Villalba, A., & Cao, A. (2021) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2021.10.045 · Cited by 17

EGLN1 prolyl hydroxylation of hypoxia-induced transcription factor HIF1α is repressed by SET7-catalyzed lysine methylation

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LDH-A Inhibitor as a Remedy to Potentiate the Anticancer Effect of Docetaxel in Prostate Cancer

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Peroxisome proliferator activated receptor (PPAR)-γ co-activator 1-α and hypoxia induced factor-1α mediate neuro- and vascular protection by hypoxic preconditioning in vitro

Zhao, J., Li, L., Pei, Z., Li, Z., Wei, H. J., Zhang, B., Peng, Y., Wang, Y., Tao, Y., & Huang, R. (2012) · Brain Research · doi:10.1016/j.brainres.2012.01.059 · Cited by 16

Increased pyruvate dehydrogenase activity in skeletal muscle of growth-restricted ovine fetuses

Pendleton, A. L., Humphreys, L. R., Davis, M. A., Camacho, L. E., Anderson, M. J., & Limesand, S. W. (2019) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00106.2019 · Cited by 16

Cellular responses in skeletal muscle to a season of ice hockey

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Identification of biological targets of therapeutic intervention for clear cell renal cell carcinoma based on bioinformatics approach

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Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes

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Effects of Metabolic Disorders in Immune Cells and Synoviocytes on the Development of Rheumatoid Arthritis

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The Effect of Metabolites on Mitochondrial Functions in the Pathogenesis of Skeletal Muscle Aging

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Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes

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The mechanism of extracellular CypB promotes glioblastoma adaptation to glutamine deprivation microenvironment

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Connexin 31 (GJB3) Deficiency in Mouse Trophoblast Stem Cells Alters Giant Cell Differentiation and Leads to Loss of Oxygen Sensing1

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Oxygen – the forgotten nutrient

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Resolving the HIF paradox in pancreatic cancer

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Oxygen Sensing, Cardiac Ischemia, HIF-1α and Some Emerging Concepts

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Hemoglobin optimization and transfusion strategies in patients undergoing cardiac surgery

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Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Deficient Cells

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Ru( ii )/BODIPY core co-encapsulated ratiometric nanotools for intracellular O 2 sensing in live cancer cells

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Invertebrates Mitochondrial Function and Energetic Challenges

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Global protein synthesis in human trophoblast is resistant to inhibition by hypoxia

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Expression of Estrogen Receptor α and β in Rat Astrocytes in Primary Culture: Effects of Hypoxia and Glucose Deprivation

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Reactive Oxygen Species in the Induction of Toxicity

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Red light photobiomodulation rescues murine brain mitochondrial respiration after acute hypobaric hypoxia

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Mitochondrial Proteomic Approaches for New Potential Diagnostic and Prognostic Biomarkers in Cancer

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Role of Glucose Transporters in Drug Membrane Transport

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Real-time in situ monitoring of Lon and Caspase-3 for assessing the state of cardiomyocytes under hypoxic conditions via a novel Au–Se fluorescent nanoprobe

Zhan, R., Guo, W., Gao, X., Liu, X., Xu, K., & Tang, B. (2021) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2021.112965 · Cited by 13

Uteroplacental nutrient flux and evidence for metabolic reprogramming during sustained hypoxemia

Jones, A. K., Rozance, P. J., Brown, L. D., Lorca, R. A., Julian, C. G., MOORE, L. G., Limesand, S. W., & Wesolowski, S. R. (2021) · Physiological Reports · doi:10.14814/phy2.15033 · Cited by 12

Mechanisms of sensing and adaptive responses to low oxygen conditions in mammals and yeasts

Trendeleva, T. A., Aliverdieva, D. A., & Zvyagilskaya, R. A. (2014) · Biochemistry (Moscow) · doi:10.1134/s0006297914080033 · Cited by 13

Disfunción mitocondrial en sepsis, impacto y posible papel regulador del factor inducible por hipoxia (HIF-1α)

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Neonatal Intermittent Hypoxia, Reactive Oxygen Species, and Oxygen-Induced Retinopathy

Beharry, K. D. A., Cai, C. L., Valencia, G., Valencia, A. M., Lazzaro, D. R., Bany-Mohammed, F., & Aranda, J. V. (2017) · doi:10.20455/ros.2017.805 · Cited by 13

The Long-Term Effects of Developmental Hypoxia on Cardiac Mitochondrial Function in Snapping Turtles

Galli, G. L. J., Ruhr, I. M., Crossley, J. L., & Crossley, D. A. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.689684 · Cited by 13

Modulation of Muscle Fiber Compositions in Response to Hypoxia via Pyruvate Dehydrogenase Kinase-1

Nguyen, D. D., Kim, G., & Pae, E. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00604 · Cited by 12

Simple and inexpensive technique for measuring oxygen consumption rate in adherent cultured cells

Takahashi, E., & Yamaoka, Y. (2017) · The Journal of Physiological Sciences · doi:10.1007/s12576-017-0563-7 · Cited by 13

Gossypitrin, A Naturally Occurring Flavonoid, Attenuates Iron-Induced Neuronal and Mitochondrial Damage

Bécquer-Viart, M. A., Armentero-López, A., Alvarez-Almiñaque, D., Fernández-Acosta, R., Matos‐Peralta, Y., D'Vries, R. F., Marín‐Prida, J., & Pardo‐Andreu, G. L. (2021) · Molecules · doi:10.3390/molecules26113364 · Cited by 12

Ethoxyquin Inhibits the Progression of Murine Ehrlich Ascites Carcinoma through the Inhibition of Autophagy and LDH

Tayel, F., Mahfouz, M. E., Salama, A. F., & Mansour, M. A. (2021) · Biomedicines · doi:10.3390/biomedicines9111526 · Cited by 12

Dual Lactate Clearance in the Viability Assessment of Livers Donated After Circulatory Death With Ex Situ Normothermic Machine Perfusion

Xu, M., Zhou, F., Ahmed, O., Randle, L. V., Shin, J.-K., Zhu, Y., Upadhya, G. A., Byrnes, K., Wong, B. W., Js, K., et al. (2021) · Transplantation Direct · doi:10.1097/txd.0000000000001243 · Cited by 12

Parthenolide targets NF-κB (P50) to inhibit HIF-1α-mediated metabolic reprogramming of HCC

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Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells

Pávez, M., & Cyganek, L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.800529 · Cited by 12

Metabolic Dysfunctions in Epilepsy and Novel Metabolic Treatment Approaches

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Cytoplasmic signaling in the control of mitochondrial uproar?

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Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

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Investigating the Mechanisms Underlying Citral-Induced Oxidative Stress and Its Contribution to Antifungal Efficacy on Magnaporthe oryzae Through a Multi-Omics Approach

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Exploiting the Role of Hypoxia-Inducible Factor 1 and Pseudohypoxia in the Myelodysplastic Syndrome Pathophysiology

Stergiou, I. Ε., Kambas, K., Poulaki, A., Giannouli, S., Κάτσιλα, Θ., Dimitrakopoulou, A., Vidali, V. P., Mouchtouris, V., Kloukina, I., Xingi, E., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084099 · Cited by 10

A shining proposal for the detection of dissolved O2 in aqueous medium: Self-calibrated optical sensing via a covalent hybrid structure of carbon-dots&Ru

Zhao, Y., Liu, X., Jiang, Y., Li, M., Wang, H., & Liu, L. (2021) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2021.120003 · Cited by 10

Engineering Tools for Regulating Hypoxia in Tumour Models

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Biological Rationale for the Use of Vertebral Whole Bone Marrow in Spinal Surgery

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Hypoxia Enhances Mesenchymal Characteristics Maintenance of Buffalo Bone Marrow-Derived Mesenchymal Stem Cells

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