The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Lateral organization of membrane proteins: tetraspanins spin their web
Abstract
Despite high expression levels at the plasma membrane or in intracellular vesicles, tetraspanins remain among the most mysterious transmembrane molecules 20 years after their discovery. Several genetic studies in mammals and invertebrates have demonstrated key physiological roles for some of these tetraspanins, in particular in the immune response, sperm–egg fusion, photoreceptor function and the normal function of certain epithelia. Other studies have highlighted their ability to modulate cell migration and metastasis formation. Their role in the propagation of infectious agents has drawn recent attention, with evidence for HIV budding in tetraspanin-enriched plasma membrane domains. Infection of hepatocytic cells by two major pathogens, the hepatitis C virus and the malaria parasite, also requires the tetraspanin CD81. The function of tetraspanins is thought to be linked to their ability to associate with one another and a wealth of other integral proteins, thereby building up an interacting network or ‘tetraspanin web’. On the basis of the biochemical dissection of the tetraspanin web and recent analysis of the dynamics of some of its constituents, we propose that tetraspanins tightly regulate transient interactions between a variety of molecules and as such favour the efficient assembly of specialized structures upon proper stimulation.
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Cites
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The pathogenesis of cancer metastasis: the ‘seed and soil’ hypothesis revisited
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Tetraspanin functions and associated microdomains
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“and Hemler, M. E. (2006) Contrasting effects of EWI proteins, integrins”
BackgroundChertova, E., Chertov, O., Coren, L. V., Roser, J. D., Trubey, C. M., Bess, J. W., Sowder, R. C., Barsov, E., Hood, B. L., Fisher, R. J., et al. (2006) · Journal of Virology · doi:10.1128/jvi.01013-06 · Cited by 462
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The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation
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CD81 Regulates Neuron-Induced Astrocyte Cell-Cycle Exit
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Cited by
van Niel, G., Charrin, S., Simoes, S., Romao, M., Rochin, L., Saftig, P., Marks, M. S., Rubinstein, E., & Raposo, G. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.08.019 · Cited by 950
Self-citationExosomes Derived from HIV-1-infected Cells Contain Trans-activation Response Element RNA
Narayanan, A., Iordanskiy, S., Das, R., Van Duyne, R., Santos, S., Jaworski, E., Guendel, I., Sampey, G., Dalby, E., Iglesias-Ussel, M., et al. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.438895 · Cited by 316
Haining, E. J., Yang, J., Bailey, R. L., Khan, K., Collier, R., Tsai, S., Watson, S. P., Frampton, J., Garcia, P., & Tomlinson, M. G. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.416503 · Cited by 163
Jouannet, S., Saint-Pol, J., Fernandez, L., Nguyen, V., Charrin, S., Boucheix, C., Brou, C., Milhiet, P.-E., & Rubinstein, E. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2111-z · Cited by 138
Self-citationWakabayashi, T., Craessaerts, K., Bammens, L., Bentahir, M., Borgions, F., Herdewijn, P., Staes, A., Timmerman, E., Vandekerckhove, J., Rubinstein, E., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1978 · Cited by 135
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Metadata
- Authors
- Charrin, S., le Naour, F., Silvie, O., Milhiet, P.-E., Boucheix, C., & Rubinstein, E.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 2009-05-13
- Volume
- 420
- Issue
- 2
- Pages
- 133-154
- ISSN
- 0264-6021 (ISSN-L)
- 1470-8728
- OpenAlex
- W1998459062
- Cited by
- 442
- References
- 8
- FWCI
- 23.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- Charrin, S., le Naour, F., Silvie, O., Milhiet, P.-E., Boucheix, C., & Rubinstein, E. (2009). Lateral organization of membrane proteins: tetraspanins spin their web. Biochemical Journal. https://doi.org/10.1042/bj20082422
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