Proteomic and Biochemical Analysis of Purified Human Immunodeficiency Virus Type 1 Produced from Infected Monocyte-Derived Macrophages

Chertova, Elena; Chertov, Oleg; Coren, Lori V.; Roser, James D.; Trubey, Charles M.; Bess, Julian W.; Sowder, Raymond C.; Barsov, Eugene; Hood, Brian L.; Fisher, Robert J.; Nagashima, Kunio; Conrads, Thomas P.; Veenstra, Timothy D.; Lifson, Jeffrey D.; Ott, David E.

doi:10.1128/jvi.01013-06

Proteomic and Biochemical Analysis of Purified Human Immunodeficiency Virus Type 1 Produced from Infected Monocyte-Derived Macrophages

Human immunodeficiency virus type 1 (HIV-1) infects CD4 + T lymphocytes and monocytes/macrophages, incorporating host proteins in the process of assembly and budding. Analysis of the host cell proteins incorporated into virions can provide insights into viral biology. We characterized proteins in…