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The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis

van Niel, Guillaume, Charrin, Stéphanie, Simoes, Sabrina, Romao, Maryse, Rochin, Leila, Saftig, Paul, Marks, Michael S., Rubinstein, Eric, Raposo, Graça·2011·Developmental Cell

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Crossref · 10.1016/j.devcel.2011.08.019

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  • The presence of ILVs within iridosomes supports an endosomal origin or an endosomal intermediate during iridosome formation and maturation.

    “Because ILVs are a hallmark of multivesicular bodies and are commonly observed during the maturation of multiple LRO types, including melanosomes and cytotoxic granules (86–88), their presence within iridosomes supports an endosomal origin or an endosomal intermediate during iridosome formation and maturation.”

    From Lysosome-related organelles orchestrate guanine crystal formation in pigment cells (2026) · cites this paper as [88]

    The Introduction (page unavailable) describes ILVs in multivesicular endosomes and identifies ILV-containing stage I premelanosomes as endosomal intermediates, supporting the analogy with melanosomes. Our copy does not address cytotoxic granules or iridosomes; the proposed origin of iridosomes is the citing authors’ inference, not a finding of this source. (LLM, conf=0.85)

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Research works printed but not linked: 45

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Metadata

Authors
van Niel, G., Charrin, S., Simoes, S., Romao, M., Rochin, L., Saftig, P., Marks, M. S., Rubinstein, E., & Raposo, G.
Venue
Developmental Cell
Publisher
Elsevier BV
Published
2011-10
Volume
21
Issue
4
Pages
708-721
ISSN
1534-5807
Cited by
950
References
2
Language
en

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