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Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues
Open accessAbstract
Capacitative calcium entry is a major pathway through which intracellular calcium stores are refilled after stimulation. It has been suggested that the protein encoded by the transient receptor potential (trp) gene expressed in Drosophila photoreceptors may be homologous with capacitative calcium entry channels. Expression of the trp gene product in Xenopus oocytes led to significant increases in calcium entry only when the intracellular calcium stores were depleted. Previous investigations have found trp to be uniquely expressed in Drosophila photoreceptors, but PCR cloning shows that homologous proteins exist in Calliphora, mouse brain and Xenopus oocytes. It is thus possible that capacitative calcium entry in Xenopus oocytes is mediated by a homologue of trp.
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Cites
Inositol trisphosphate and calcium signalling
Berridge, M. J. (1993) · Nature · doi:10.1038/361315a0 · Cited by 6,545
Self-citation
Cited by
Store-Operated Calcium Channels
Parekh, A. B., & Putney, J. W. (2005) · Physiological Reviews · doi:10.1152/physrev.00057.2003 · Cited by 2,089
Store-Operated Calcium Channels
Prakriya, M., & Lewis, R. S. (2015) · Physiological Reviews · doi:10.1152/physrev.00020.2014 · Cited by 1,239
Elementary and global aspects of calcium signalling.
Berridge, M. J. (1997) · The Journal of Physiology · doi:10.1113/jphysiol.1997.sp021927 · Cited by 1,018
Self-citationThe TRP Superfamily of Cation Channels
Montell, C. (2005) · Science's STKE · doi:10.1126/stke.2722005re3 · Cited by 989
trp, a Novel Mammalian Gene Family Essential for Agonist-Activated Capacitative Ca2+ Entry
Zhu, X., Jiang, M., Peyton, M., Boulay, G., Hurst, R., Stefani, E., & Birnbaumer, L. (1996) · Cell · doi:10.1016/s0092-8674(00)81233-7 · Cited by 685
Metadata
- Authors
- Petersen, C. C., Berridge, M. J., Borgese, M. F., & Bennett, D. L.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1995-10-01
- Volume
- 311
- Issue
- 1
- Pages
- 41-44
- ISSN
- 0264-6021 (ISSN-L)
- 1470-8728
- OpenAlex
- W1859293501
- Cited by
- 188
- References
- 1
- FWCI
- 13.43
- Type
- journal article
- Language
- en
- Open access
- green
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- Petersen, C. C., Berridge, M. J., Borgese, M. F., & Bennett, D. L. (1995). Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues. Biochemical Journal. https://doi.org/10.1042/bj3110041
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