Early life programming of energy balance
Abstract
Obesity prevalence is increasing worldwide, leading to increased morbidity, mortality and health care costs due to its role as a key risk factor in many diseases. Early life growth and nutrition has been implicated in determining susceptibility to obesity in both childhood and adulthood; however, the mechanisms underlying this link are poorly understood. A variety of animal models have been established to try and uncover the developmental programming effects of maternal early life nutrition on energy balance regulation and the mechanisms behind them.
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Besides classical genetic, epigenetic and nongenetic mechanisms could also be potentially responsible for differences in neural reward circuitry and reward behaviors at a young age, predisposing to hyperphagia and obesity later in life.
“Besides classical genetic, epigenetic and nongenetic mechanisms ([23](#B23), [34](#B34), [36](#B36), [37](#B37), [62](#B62), [67](#B67), [126](#B126), [155](#B155), [176](#B176), [184](#B184)) could also be potentially responsible for differences in neural reward circuitry and reward behaviors at a young age, predisposing to hyperphagia and obesity later in life.”
From Food reward, hyperphagia, and obesity (2011) · cites this paper as [34]
Cites
Obesity in Young Men after Famine Exposure in Utero and Early Infancy
Ravelli, G.-P., Stein, Z. A., & Susser, M. W. (1976) · New England Journal of Medicine · doi:10.1056/nejm197608122950701 · Cited by 1,647 · see citing works
Trophic Action of Leptin on Hypothalamic Neurons That Regulate Feeding
Bouret, S. G., Draper, S. J., & Simerly, R. B. (2004) · Science · doi:10.1126/science.1095004 · Cited by 1,219 · see citing works
Duration of Breastfeeding and Risk of Overweight: A Meta-Analysis
Harder, T., Bergmann, R. L., Kallischnigg, G., & Plagemann, A. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi222 · Cited by 1,150 · see citing works
Vickers, M. H., Breier, B. H., Cutfield, W. S., Hofman, P. L., & Gluckman, P. D. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.1.e83 · Cited by 999 · see citing works
Cellular Response in Rats during Malnutrition at Various Ages
Winick, M., & Noble, A. (1966) · Journal of Nutrition · doi:10.1093/jn/89.3.300 · Cited by 959 · see citing works
Ahima, R. S., Prabakaran, D., & Flier, J. S. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1176 · Cited by 627 · see citing works
Neonatal Leptin Treatment Reverses Developmental Programming
Vickers, M. H., Gluckman, P. D., Coveny, A. H., Hofman, P. L., Cutfield, W. S., Gertler, A., Breier, B. H., & Harris, M. A. (2005) · Endocrinology · doi:10.1210/en.2005-0581 · Cited by 616 · see citing works
Weight Gain in the First Week of Life and Overweight in Adulthood
Stettler, N., Stallings, V. A., Troxel, A. B., Zhao, J., Schinnar, R., Nelson, S. E., Ziegler, E. E., & Strom, B. L. (2005) · Circulation · doi:10.1161/01.cir.0000161797.67671.a7 · Cited by 441 · see citing works
Vickers, M. H., Breier, B. H., McCarthy, D., & Gluckman, P. D. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00051.2003 · Cited by 346 · see citing works
Kensara, O. A., Wootton, S. A., Phillips, D. I., Patel, M., Jackson, A. A., & Elia, M. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.5.980 · Cited by 252 · see citing works
Ong, K. K., Kratzsch, J., Kieß, W., Costello, M., Scott, C. D., & Dunger, D. B. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.11.6998 · Cited by 228 · see citing works
Ozanne, S. E., Lewis, R. M., Jennings, B. J., & Hales, C. N. (2004) · Clinical Science · doi:10.1042/cs20030278 · Cited by 148 · see citing works
Self-citationPredictors of abdominal obesity among 31-y-old men and women born in Northern Finland in 1966
Laitinen, J. H., Pietiläinen, K. H., Wadsworth, M. E. J., Sovio, U., & Järvelin, M. (2003) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1601765 · Cited by 125 · see citing works
Davidowa, H., Li, Y., & Plagemann, A. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02789.x · Cited by 123 · see citing works
Kensara, O. A., Wootton, S. A., Phillips, D. I. W., Patel, M., Hoffman, D. J., Jackson, A. A., & Elia, M. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00599.2005 · Cited by 52 · see citing works
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Food reward, hyperphagia, and obesity
Berthoud, H.-R., Lenard, N. R., & Shin, A. C. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00028.2011 · Cited by 275 · see citing works
- Authors
- Cripps, R. L., Archer, Z. A., Mercer, J. G., & Ozanne, S. E.
- Affiliations
- University of Cambridge (GB)
- Division of Obesity and Metabolic Health, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, U.K.
- Venue
- Biochemical Society Transactions
- Publisher
- Portland Press Ltd.
- Published
- 2007-10-25
- Volume
- 35
- Issue
- 5
- Pages
- 1203-1204
- ISSN
- 0300-5127 (ISSN-L)
- 1470-8752
- OpenAlex
- W1982064481
- Cited by
- 9
- References
- 15
- Citations by year
- 2022: 1 · 2018: 1 · 2014: 1
- FWCI
- 0.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biochemical Society Transactions (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Biotechnology and Biological Sciences Research Council (BB/E00797X/1)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Syndromes and Imprinting
- Keywords
- early life programming, energy balance, obesity, maternal nutrition, developmental programming, child growth, energy balance regulation, animal models of obesity
- MeSH terms
- Animals, Energy Metabolism, Humans, Models, Animal
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