The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
MicroRNA in erythrocytes.
Abstract
Mammalian erythrocytes are generally thought to lack RNA and therefore to be unable to translate new proteins in response to internal or external signals. Support for this long-standing view has accumulated from diverse studies, most of which have focused on the total content of RNA or the overall level of translation. However, more recent work on specific types of RNA has shown the presence in human erythrocytes of both Y RNA and microRNA. The latter seem particularly incongruous given that their normal role is to attenuate the translation of mRNA. Y RNA binds the Ro autoantigen which may have a role in cellular RNA quality control. Therefore the presence of both of these non-coding RNAs indicates the possible existence of other cryptic RNAs in erythrocytes. It also suggests either the existence of low levels of translation or new uncharacterized processes involving microRNA in these cells.
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“Interestingly, many miRNAs that are up- or downregulated during erythropoiesis may not be removed or degraded but selectively retained in mature red blood cells (RBCs)”
From Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System (2020) · cites this paper as Hamilton, 2010
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“MiRNAs in erythrocytes have a very unique expression pattern compared with human reticulocytes, which indicates that miRNAs are likely selectively retained and function in mature RBCs”
From Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System (2020) · cites this paper as Hamilton, 2010
In the citing paper
“which indicates that miRNAs are likely selectively retained and function in mature RBCs”
From Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System (2020) · cites this paper as Hamilton, 2010
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Cites
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Cited by
Sorted by citations
Red Blood Cells as Potential Repositories of MicroRNAs in the Circulatory System
Sun, L., Yu, Y., Niu, B., & Wang, D. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00442 · Cited by 83
Metadata
- Authors
- Hamilton, A. J.
- Affiliations
- Division of Cancer Science and Molecular Pathology, Glasgow University, Western Infirmary (Pathology), Dumbarton Road, Glasgow G11 6NT, U.K.
- Venue
- Biochemical Society Transactions
- Publisher
- Portland Press Ltd.
- Published
- 2010-01-19
- Volume
- 38
- Issue
- 1
- Pages
- 229-231
- ISSN
- 0300-5127
- 1470-8752
- Cited by
- 32
- References
- 1
- Language
- en
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