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Cited by 362Cardiovascular and exercise physiologyObesity, Physical Activity, DietPhysical Activity and Health

The DOI matches its Crossref record; 43 of the 44 references it cites were found in a registry or an index.

Aerobic interval training reduces cardiovascular risk factors more than a multitreatment approach in overweight adolescents

Tjønna, Arnt E., Stølen, Tomas O., Bye, Anja, Volden, Marte, Slørdahl, Stig A., Ødegård, Rønnaug, Skogvoll, Eirik, Wisløff, Ulrik·2009·Clinical Science
DOI 10.1042/cs20080249
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Abstract

The aim of the present study was to compare the effects of a multidisciplinary approach (MTG) and aerobic interval training (AIT) on cardiovascular risk factors in overweight adolescents. A total of 62 overweight and obese adolescents from Trøndelag County in Norway, referred to medical treatment at St Olav's Hospital, Trondheim, Norway, were invited to participate. Of these, 54 adolescents (age, 14.0±0.3 years) were randomized to either AIT (4×4 min intervals at 90% of maximal heart rate, each interval separated by 3 min at 70%, twice a week for 3 months) or to MTG (exercise, dietary and psychological advice, twice a month for 12 months). Follow-up testing occurred at 3 and 12 months. V̇O2max (maximal oxygen uptake) increased more after AIT compared with MTG, both at 3 months (11 compared with 0%; P<0.01) and 12 months (12 compared with −1%; P<0.01). AIT enhanced endothelial function compared with MTG at both 3 months (absolute change, 5.1 compared with 3.9%; P<0.01) and 12 months (absolute change, 6.3 compared with 1.0%; P<0.01). AIT was favourable compared with MTG in reducing BMI (body mass index), percentage of fat, MAP (mean arterial blood pressure) and increasing peak oxygen pulse. In addition, AIT induced a more favourable regulation of blood glucose and insulin compared with MTG. In conclusion, the novel findings of the present proof-of-concept study was that 3 months of twice weekly high-intensity exercise sessions reduced several known cardiovascular risk factors in obese adolescents more than that observed after a multitreatment strategy, which was initiated as hospital treatment. Follow-up at 12 months confirmed that AIT improved or maintained these risk factors to a better degree than MTG.

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Crossref · 10.1042/cs20080249

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Metadata

Authors
Tjønna, A. E., Stølen, T. O., Bye, A., Volden, M., Slørdahl, S. A., Ødegård, R., Skogvoll, E., & Wisløff, U.
Affiliations
  • Norwegian University of Science and Technology (NO)
  • St Olav's University Hospital (NO)
Corresponding author
Bye, Anja
ORCID
Venue
Clinical Science
Publisher
Portland Press Ltd.
Published
2009-01-15
Volume
116
Issue
4
Pages
317-326
ISSN
  • 0143-5221 (ISSN-L)
  • 1470-8736
DOI
10.1042/cs20080249
OpenAlex
W2090684648
Cited by
362
References
44
Citations by year
2026: 3 · 2025: 16 · 2024: 14 · 2023: 15 · 2022: 29 · 2021: 19 · 2020: 29 · 2019: 24 · 2018: 20 · 2017: 22 · 2016: 21 · 2015: 41 · 2014: 32 · 2013: 34 · 2012: 17
FWCI
24.40
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Keywords
aerobic interval training, high-intensity exercise, cardiovascular risk factors, adolescent obesity, adolescent overweight, multidisciplinary treatment, exercise therapy, endothelial function, VO2max, blood pressure, insulin regulation, blood glucose, body mass index, body fat percentage, peak oxygen pulse
MeSH terms
Adolescent, Anthropometry, Blood Glucose, Blood Pressure, Body Composition, Cardiovascular Diseases, Combined Modality Therapy, Diet, Exercise Therapy, Feeding Behavior, Female, Humans, Cholesterol, HDL, Male, Obesity, Oxygen Consumption, Patient Compliance, Risk Factors, Body Mass Index, Overweight

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