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Occlusion vs. skin barrier function
Abstract
Background/aims: Skin occlusion may increase percutaneous absorption of applied chemicals, with some exceptions. It also obstructs the normal ventilation of the skin surface and increases stratum corneum hydration and hence compromises skin barrier function. Methods/results: This review focuses the effects of occlusion on skin barrier function, in particularly, as defined with objective skin bioengineering technology. Conclusions: The effects of occlusion on skin barrier function have been defined with various techniques. Optimal hydrocolloid materials can absorb excess water and reduce the unfavourable effects of occlusion.
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Citations
Cited by
Cross, S. E., Innes, B., Roberts, M. S., Tsuzuki, T., Robertson, T. A., & McCormick, P. (2007) · Skin Pharmacology and Physiology · doi:10.1159/000098701 · Cited by 481
The clinical benefit of moisturizers
Lodén, M. (2005) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2005.01326.x · Cited by 255
Tagami, H. (2008) · International Journal of Cosmetic Science · doi:10.1111/j.1468-2494.2008.00459.x · Cited by 195
Effect of moisturizers on epidermal barrier function
Lodén, M. (2012) · Clinics in Dermatology · doi:10.1016/j.clindermatol.2011.08.015 · Cited by 161
Franz diffusion cell and its implication in skin permeation studies
Kumar, M., Sharma, A., Mahmood, S., Thakur, A., Mirza, M. A., & Bhatia, A. (2024) · Journal of Dispersion Science and Technology · doi:10.1080/01932691.2023.2188923 · Cited by 99
Metadata
- Authors
- Zhai, H., & Maibach, H. I.
- Venue
- Skin Research and Technology
- Publisher
- Wiley
- Published
- 2002-02
- Volume
- 8
- Issue
- 1
- Pages
- 1-6
- ISSN
- 0909-752X (ISSN-L)
- 1600-0846
- OpenAlex
- W1599946661
- Cited by
- 219
- References
- 0
- FWCI
- 3.06
- Type
- journal article
- Language
- en
- Open access
- closed
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