The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
A follow-up study of recurrence and cosmesis in completely responding superficial and nodular basal cell carcinomas treated with methyl 5-aminolaevulinate-based photodynamic therapy alone and with prior curettage
Abstract
BACKGROUND: Methyl 5-aminolaevulinate (mALA) is an ester derivative of 5-aminolaevulinic acid (ALA) with increased lipophilicity compared with ALA. OBJECTIVES: To assess long-term cure rate, cosmesis, recurrence rate and extent of fibrosis after mALA-based photodynamic therapy (PDT) of superficial and nodular basal cell carcinomas (BCCs) showing early complete response to treatment. METHODS: Of 350 BCCs treated, 310 responded completely. These were in 59 patients who were followed for 2-4 years (mean 35 months) after mALA-PDT. Nodular tumours were curetted before PDT, and mALA 160 mg g(-1) was applied to all tumours for 24 h or 3 h before illumination from a broad-band halogen light source with light doses from 50 to 200 J cm(-2). Fibrosis was assessed histologically in 23 biopsies. RESULTS: The overall cure rate for 350 BCCs, including non-responders and recurrences was 79%. Of 310 lesions, 277 (89%) remained in complete response, and the cosmetic outcome was excellent or good in 272 of the completely responding lesions (98%). Histological examination showed dermal fibrosis in one of 23 biopsies. CONCLUSIONS: We conclude that mALA-based PDT with prior curettage of nodular lesions is a promising new method for the treatment of BCC.
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Cites
Photodynamic therapy with endogenous protoporphyrin
Kennedy, J. C., Pottier, R. H., & Pross, D. C. (1990) · Journal of Photochemistry and Photobiology B: Biology · doi:10.1016/1011-1344(90)85083-9 · Cited by 1,509
Fritsch, C., Homey, B., Stahl, W., Lehmann, P., Ruzicka, T., & Sies, H. (1998) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1998.tb02492.x · Cited by 192
DISTRIBUTION OF 5‐AMINOLEVULINIC ACID‐INDUCED PORPHYRINS IN NODULOULCERATIVE BASAL CELL CARCINOMA
Peng, Q., Warloe, T., Moan, J., Heyerdahl, H., Steen, H. B., Nesland, J. M., & Giercksky, K. (1995) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1995.tb09154.x · Cited by 178
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The present and future role of photodynamic therapy in cancer treatment
Brown, S. B., Brown, E. A., & Walker, I. (2004) · The Lancet Oncology · doi:10.1016/s1470-2045(04)01529-3 · Cited by 1,771
Guidelines for the management of basal cell carcinoma
Telfer, N. R., Colver, G. B., & Morton, C. A. (2008) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2008.08666.x · Cited by 960
Rhodes, L. E., de Rie, M., Enström, Y., Groves, R., Morken, T., Goulden, V., Wong, G. A. E., Grob, J.-J., Varma, S., & Wolf, P. (2004) · Archives of Dermatology · doi:10.1001/archderm.140.1.17 · Cited by 355
Current evidence and applications of photodynamic therapy in dermatology
Lin, J., & Wan, M. T. (2014) · Clinical, Cosmetic and Investigational Dermatology · doi:10.2147/ccid.s35334 · Cited by 248
Szeimies, R., Ibbotson, S., Murrell, D., Rubel, D., Frambach, Y., De Berker, D., Dummer, R., Kerrouche, N., Villemagne, H., & on behalf of the Excilight Study Group (2008) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2008.02803.x · Cited by 247
Metadata
- Authors
- Soler, A. M., Warloe, T., Berner, A., & Giercksky, K. E.
- Venue
- British Journal of Dermatology
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-09
- Volume
- 145
- Issue
- 3
- Pages
- 467-471
- ISSN
- 0007-0963 (ISSN-L)
- 1365-2133
- OpenAlex
- W2122474263
- Cited by
- 219
- References
- 3
- FWCI
- 5.23
- Type
- journal article
- Language
- en
- Open access
- closed
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- Soler, A. M., Warloe, T., Berner, A., & Giercksky, K. E. (2001). A follow-up study of recurrence and cosmesis in completely responding superficial and nodular basal cell carcinomas treated with methyl 5-aminolaevulinate-based photodynamic therapy alone and with prior curettage. British Journal of Dermatology. https://doi.org/10.1046/j.1365-2133.2001.04407.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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