Having lived on a farm and protection against allergic diseases in Australia

Reduced risk of hay fever and asthma among children of farmers

Ehrenstein, V., Mutius, V., Illi, Baumann, Böhm, & Kries, V. (2000) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2000.00801.x · Cited by 718 · see citing works

Exposure to foodborne and orofecal microbes versus airborne viruses in relation to atopy and allergic asthma: epidemiological study

Matricardi, P. M. (2000) · BMJ · doi:10.1136/bmj.320.7232.412 · Cited by 694 · see citing works

Prevalence of hay fever and allergic sensitization in farmer's children and their peers living in the same rural community

Braun‐Fahrländer, GASSNER, GRIZE, NEU, SENNHAUSER, VARONIER, VUILLE, Wüthrich, & THE SCARPOL TEAM (1999) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.1999.00479.x · Cited by 660 · see citing works

Austrian children living on a farm have less hay fever, asthma and allergic sensitization

Riedler, Eder, Oberfeld, & Schreuer (2000) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2000.00799.x · Cited by 586 · see citing works

Respiratory Health Hazards in Agriculture

(1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.supplement_1.rccm1585s1 · Cited by 495 · see citing works

Allergic respiratory disease: strategic targets for primary prevention during childhood

Holt, P. G., & Sly, P. D. (1997) · Thorax · doi:10.1136/thx.52.1.1 · Cited by 469 · see citing works

Farm environment in childhood prevents the development of allergies

Kilpeläinen, Terho, Helenius, & Koskenvuo (2000) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2000.00800.x · Cited by 370 · see citing works

Atopic versus infectious diseases in childhood: a question of balance?

Holt, P. G., Sly, P. D., & Björksién, B. (1997) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.1997.tb00145.x · Cited by 309 · see citing works

Bronchial hyperresponsiveness in two populations of Australian schoolchildren. I. Relation to respiratory symptoms and diagnosed asthma

SALOME, C. M., Peat, J. K., Britton, W. J., & Woolcock, A. J. (1987) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.1987.tb02015.x · Cited by 280 · see citing works

Salmonella typhimurium DT104: a virulent and drug-resistant pathogen.

Poppe, C., Smart, N., Khakhria, R., Johnson, W. M., Spika, J. S., & Prescott, J. F. (1998) · Europe PMC (PubMed Central) · Cited by 172 · see citing works

Prevalence and severity of childhood asthma and allergic sensitisation in seven climatic regions of New South Wales

Peat, J. K., Toelle, B. G., Gray, E. J., Haby, M. M., Belousova, E., Mellis, C. M., & Woolcock, A. J. (1995) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1995.tb126083.x · Cited by 123 · see citing works

Failed or misleading adjustment for confounding

Leon, D. A. (1993) · The Lancet · doi:10.1016/0140-6736(93)91599-h · Cited by 69 · see citing works

Reliability of a Respiratory History Questionnaire and Effect of Mode of Administration on Classification of Asthma in Children

Peat, J. K., Salome, C. M., Toelle, B. G., Bauman, A. E., & Woolcock, A. J. (1992) · CHEST Journal · doi:10.1378/chest.102.1.153 · Cited by 64 · see citing works

Exposure to grain dust and changes in lung function.

James, A. L., Zimmerman, M. J., Ee, H., RYAN, G. F., & Musk, A. W. (1990) · Occupational and Environmental Medicine · doi:10.1136/oem.47.7.466 · Cited by 52 · see citing works

Vero cytotoxin-producing E coli 0157 infection associated with farms

Wb, T., Willshaw, G. A., CHEASTY, T., WRAY, C., & Gallagher, J. S. (1996) · The Lancet · doi:10.1016/s0140-6736(96)91593-7 · Cited by 39 · see citing works

Effects of exposure to external ionizing radiation on cancer mortality in nuclear workers monitored for radiation at rocketdyne/atomics international

Ritz, B. R., Morgenstern, H., Froines, J. R., & Young, B. B. (1999) · American Journal of Industrial Medicine · doi:10.1002/(sici)1097-0274(199901)35:1 · Cited by 37 · see citing works

Fungal flora associated with combine harvester wheat and sorghum dusts from Egypt

Abdel‐Hafez, S. I. I., Moubasher, A. H., Shoreit, A. A. M., & Ismail, M. (1990) · Journal of Basic Microbiology · doi:10.1002/jobm.3620300702 · Cited by 35 · see citing works

Exposure to an abundance of cat (Fel d 1) and dog (Can f 1) allergens in Swedish farming households

Parvaneh, S., Kronqvist, M., Johansson, E., & van Hage, M. (1999) · Allergy · doi:10.1034/j.1398-9995.1999.00855.x · Cited by 31 · see citing works

Animals and allergy

Lewis, S. (2000) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2000.00802.x · Cited by 30 · see citing works

Epidemiology of infection due to Escherichia coli O157: a 3-year prospective study

Macdonald, I. A., Gould, I. M., & Curnow, J. (1996) · Epidemiology and Infection · doi:10.1017/s0950268800052584 · Cited by 22 · see citing works

Seasonal variation in non-specific bronchial reactivity: a study of wheat workers with a history of wheat associated asthma.

Hensley, M. J., Scicchitano, R., Saunders, N. A., Cripps, A. W., Ruhno, J. W., Sutherland, D., & Clancy, R. L. (1988) · Thorax · doi:10.1136/thx.43.2.103 · Cited by 22 · see citing works

Pulmonary Reactive Components of Winter Wheat Grain Dust at Colorado Farms and Elevators

Beard, M. D., Buchan, R. M., Reeves, F. B., & Salasek, M. L. (1996) · Applied Occupational and Environmental Hygiene · doi:10.1080/1047322x.1996.10389438 · Cited by 9 · see citing works

Accidents related to manure in eastern Switzerland: an epidemiological study.

Knoblauch, A., Steiner, B., Bachmann, S. P., Trachsler, G., Burgheer, R., & Osterwalder, J. (1996) · Occupational and Environmental Medicine · doi:10.1136/oem.53.9.577 · Cited by 3 · see citing works

Air-spora of the crop fields and its applications.

Sreeramulu, T. (1970) · Cited by 2 · see citing works

The germless theory of allergic disease: revisiting the hygiene hypothesis

Wills-Karp, M. A., Santeliz, J., & Karp, C. L. (2001) · Nature reviews. Immunology · doi:10.1038/35095579 · Cited by 788 · see citing works

Farm living: effects on childhood asthma and allergy

von Mutius, E., & Vercelli, D. (2010) · Nature reviews. Immunology · doi:10.1038/nri2871 · Cited by 697 · see citing works

International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis

Wise, S. K., Lin, S. Y., Toskala, E., Orlandi, R. R., Akdis, C. A., Alt, J. A., Azar, A., Baroody, F. M., Bachert, C., Canonica, G. W., et al. (2018) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22073 · Cited by 557 · see citing works

International consensus statement on allergy and rhinology: Allergic rhinitis – 2023

Wise, S. K., Damask, C. C., Roland, L. T., Ebert, C. S., Levy, J. M., Lin, S. Y., Luong, A., Rodriguez, K., Sedaghat, A. R., Toskala, E. M., et al. (2023) · International Forum of Allergy & Rhinology · doi:10.1002/alr.23090 · Cited by 554 · see citing works

Endotoxin Exposure Is a Risk Factor for Asthma

Thorne, P. S., Kulhánková, K., Yin, M., Cohn, R. D., Arbes, S. J., & Zeldin, D. C. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200505-758oc · Cited by 339 · see citing works

Not all farming environments protect against the development of asthma and wheeze in children

Ege, M. J., Frei, R., Bieli, C., Schram-Bijkerk, D., Waser, M., Benz, M. R., Weiss, G., Nyberg, F., van Hage, M., Pershagen, G., et al. (2007) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2007.01.037 · Cited by 294 · see citing works

Inverse association of farm milk consumption with asthma and allergy in rural and suburban populations across Europe

Waser, M., Michels, K. B., Bieli, C., Flöistrup, H., Pershagen, G., von Mutius, E., Ege, M. J., Riedler, J., Schram-Bijkerk, D., Brunekreef, B., et al. (2006) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2006.02640.x · Cited by 280 · see citing works

House Dust Endotoxin and Allergic Sensitization in Children

Gehring, U., Bischof, W., Fahlbusch, B., Wichmann, H. ‐., & Heinrich, J. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200203-256oc · Cited by 229 · see citing works

Which aspects of the farming lifestyle explain the inverse association with childhood allergy?

Perkin, M. R., & Strachan, D. P. (2006) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2006.03.008 · Cited by 223 · see citing works

Do farming exposures cause or prevent asthma? Results from a study of adult Norwegian farmers

Eduard, W. (2004) · Thorax · doi:10.1136/thx.2004.013326 · Cited by 220 · see citing works

The microbial environment and its influence on asthma prevention in early life

von Mutius, E. (2016) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2015.12.1301 · Cited by 199 · see citing works

Farm residence and exposures and the risk of allergic diseases in New Zealand children

Wickens, K., Lane, J. M., Fitzharris, P., Siebers, R., Riley, G., Douwes, J., Smith, T., & Crane, J. (2002) · Allergy · doi:10.1034/j.1398-9995.2002.t01-1-23644.x · Cited by 184 · see citing works

Exposure and respiratory health in farming in temperate zones--a review of the literature.

Omland, Ø. (2002) · PubMed · Cited by 174 · see citing works

Trends in asthma, allergic rhinitis and eczema among Swedish conscripts from farming and non‐farming environments. A nationwide study over three decades

Bråbäck, L., Hjern, A., & Rasmussen, F. (2004) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2004.01841.x · Cited by 169 · see citing works

The hygiene hypothesis in allergy and asthma

Brooks, C., Pearce, N. E., & Douwes, J. E. (2012) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e32835ad0d2 · Cited by 167 · see citing works

Living on a Farm: Impact on Asthma Induction and Clinical Course

von Mutius, E., & Radon, K. (2008) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2008.03.010 · Cited by 162 · see citing works

Indoor air pollution and childhood asthma: variations between urban and rural areas

Flamant‐Hulin, M., Caillaud, D. M., & Annesi‐Maesano, I. (2010) · Indoor Air · doi:10.1111/j.1600-0668.2010.00673.x · Cited by 160 · see citing works

Does environmental endotoxin exposure prevent asthma?

Douwes, J. E. (2002) · Thorax · doi:10.1136/thorax.57.1.86 · Cited by 154 · see citing works

Prevalence of allergy, patterns of allergic sensitization and allergy risk factors in rural and urban children

Majkowska–Wojciechowska, B., Pełka, J., Korzon, L., Kozłowska, A., Kaczała, M., Jarzębska, M., Gwardys, T., & Kowalski, M. L. (2007) · Allergy · doi:10.1111/j.1398-9995.2007.01457.x · Cited by 148 · see citing works

Asthma and Farm Exposures in a Cohort of Rural Iowa Children

Merchant, J. A., Naleway, A. L., Svendsen, E. R., Kelly, K. M., Burmeister, L. F., Stromquist, A. M., Taylor, C. D., Thorne, P. S., Reynolds, S. J., Sanderson, W. T., et al. (2004) · Environmental Health Perspectives · doi:10.1289/ehp.7240 · Cited by 149 · see citing works

Bacterial and fungal agents in house dust and wheeze in children: the PARSIFAL study

Schram-Bijkerk, D., Doekes, G., Douwes, J. E., Boeve, M., Riedler, J., Üblagger, E., von Mutius, E., Benz, M. R., Pershagen, G., van Hage, M., et al. (2005) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2005.02339.x · Cited by 143 · see citing works

Environmental factors associated with allergy in urban and rural children from the South African Food Allergy (SAFFA) cohort

Levin, M. E., Botha, M., Basera, W., Facey‐Thomas, H. E., Gaunt, B., Gray, C. L., Kiragu, W., Ramjith, J., Watkins, A., & Genuneit, J. (2019) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2019.07.048 · Cited by 135 · see citing works

Asthma and the westernization ‘package’

Douwes, J. E., & Pearce, N. E. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.6.1098 · Cited by 133 · see citing works

Bacterial and fungal components in house dust of farm children, Rudolf Steiner school children and reference children – the PARSIFAL Study

Schram-Bijkerk, D., Doekes, G., Boeve, M., Douwes, J. E., Riedler, J., Üblagger, E., von Mutius, E., Budde, J., Pershagen, G., Nyberg, F., et al. (2005) · Allergy · doi:10.1111/j.1398-9995.2005.00748.x · Cited by 125 · see citing works

Comparative Study of Food Allergies in Children from China, India, and Russia: The EuroPrevall-INCO Surveys

Li, J., Ogorodova, L. M., Mahesh, P. A., Wang, M. H., Fedorova, O. S., Leung, T. F., Fernández‐Rivas, M., Mills, E. N. C., Potts, J., Kummeling, I., et al. (2019) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2019.11.042 · Cited by 123 · see citing works

Which factors explain the lower prevalence of atopy amongst farmers' children?

Remes, S. T., Iivanainen, K., Koskela, H., & Pekkanen, J. (2003) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2003.01566.x · Cited by 121 · see citing works

Environmental exposure to endotoxin and other microbial products and the decreased risk of childhood atopy: evaluating developments since April 2002

Braun‐Fahrländer, C. (2003) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/00130832-200310000-00001 · Cited by 117 · see citing works

Exposure to farming environments in childhood and asthma and wheeze in rural populations: a systematic review with meta‐analysis

Genuneit, J. (2012) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2012.01312.x · Cited by 116 · see citing works

Determinants of endotoxin levels in living environments of farmers' children and their peers from rural areas

Waser, M., Schierl, R., von Mutius, E., Maisch, S., Carr, D., Riedler, J., Eder, W., Schreuer, M., Nowak, D., Braun‐Fahrländer, C., et al. (2004) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2004.01873.x · Cited by 106 · see citing works

Characterization of the Microbial Community in Indoor Environments: a Chemical-Analytical Approach

Sebastian, A., & Larsson, L. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.6.3103-3109.2003 · Cited by 104 · see citing works

The role of lipopolysaccharide in the development of atopy in humans

Simpson, A., & Martinez, F. D. (2010) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2009.03391.x · Cited by 94 · see citing works

Asthma and Allergies in Rural Areas of Europe

von Mutius, E. (2007) · Proceedings of the American Thoracic Society · doi:10.1513/pats.200701-028aw · Cited by 94 · see citing works

Asthma prevalence and morbidity among rural Iowa schoolchildren

Chrischilles, E. A., Ahrens, R. C., Kuehl, A. K., Kelly, K. M., Thorne, P. S., Burmeister, L. F., & Merchant, J. A. (2004) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2003.09.037 · Cited by 86 · see citing works

THE TWO SIDES OF THE “ENDOTOXIN COIN”

Radon, K. (2005) · Occupational and Environmental Medicine · doi:10.1136/oem.2004.017616 · Cited by 86 · see citing works

99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Farm lifestyles and the hygiene hypothesis

von Mutius, E. (2010) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2010.04138.x · Cited by 81 · see citing works

Very low prevalence of asthma and allergies in schoolchildren from rural Beijing, China

Ma, Y., Zhao, J., Han, Z., Chen, Y., Leung, T. F., & Wong, G. (2009) · Pediatric Pulmonology · doi:10.1002/ppul.21061 · Cited by 76 · see citing works

Decreased prevalence of asthma among farm-reared children compared with those who are rural but not farm-reared

Adler, A. G., Tager, I. B., & Quintero, D. R. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2004.10.008 · Cited by 74 · see citing works

Four-year incidence of allergic sensitization among schoolchildren in a community where allergy to cat and dog dominates sensitization

Rönmark, E., Perzanowski, M., Platts‐Mills, T. A. E., & Lundbäck, B. (2003) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(03)01866-9 · Cited by 71 · see citing works

Atopic and non‐atopic asthma in a farming and a general population

Eduard, W., Omenaas, E. R., Bakke, P. S., Douwes, J. E., & Heederik, D. J. J. (2004) · American Journal of Industrial Medicine · doi:10.1002/ajim.20088 · Cited by 69 · see citing works

Raw Cow’s Milk and Its Protective Effect on Allergies and Asthma

Sozańska, B. (2019) · Nutrients · doi:10.3390/nu11020469 · Cited by 66 · see citing works

Early childhood environment related to microbial exposure and the occurrence of atopic disease at school age

de Meer, G., Janssen, N., & Brunekreef, B. (2005) · Allergy · doi:10.1111/j.1398-9995.2005.00746.x · Cited by 66 · see citing works

Asthma and Atopy in Rural Children: Is Farming Protective?

Naleway, A. L. (2004) · Clinical Medicine & Research · doi:10.3121/cmr.2.1.5 · Cited by 65 · see citing works

Assessment of endotoxin levels in the home and current asthma and wheeze in school-age children

Rennie, D., Lawson, J. A., Kirychuk, S., Paterson, C. P., Willson, P. J., Senthilselvan, A., & Cockcroft, D. W. (2008) · Indoor Air · doi:10.1111/j.1600-0668.2008.00543.x · Cited by 64 · see citing works

Maintaining health by balancing microbial exposure and prevention of infection: the hygiene hypothesis versus the hypothesis of early immune challenge

Krämer, A., Bekeschus, S., Bröker, B. M., Schleibinger, H., Razavi, B., & Assadian, O. (2013) · Journal of Hospital Infection · doi:10.1016/s0195-6701(13)60007-9 · Cited by 64 · see citing works

Prevalence of symptoms of asthma, rhinitis, and atopic eczema among adolescents living in urban and rural areas in different regions of Brazil

Solé, D., Cassol, V. E., Silva, A. R., Teche, S. P., Rizzato, T. M., Bandim, L. C., Sarinho, E. S. C., & Camelo‐Nunes, I. C. (2007) · Allergologia et Immunopathologia · doi:10.1157/13112991 · Cited by 64 · see citing works

Maternal farm exposure/ingestion of unpasteurized cowʼs milk and allergic disease

von Mutius, E. (2012) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e32835955d3 · Cited by 63 · see citing works

Prevalence of Atopy and Allergic Diseases in Korean Children: Associations with a Farming Environment and Rural Lifestyle

Lee, S. Y., Kwon, J., Seo, J., Song, Y. H., Kim, B., Yu, J., Park, K. S., Kim, H., Kim, E.-K., Lee, J. S., et al. (2012) · International Archives of Allergy and Immunology · doi:10.1159/000330820 · Cited by 61 · see citing works

The Urban-Rural Gradient In Asthma: A Population-Based Study in Northern Europe

Timm, S., Frydenberg, M., Janson, C., Campbell, B., Forsberg, B., Gíslason, Þ., Holm, M., Jögi, R., Omenaas, E. R., Sigsgaard, T., et al. (2015) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph13010093 · Cited by 61 · see citing works

Exposure to ‘farming’ and objective markers of atopy: a systematic review and meta‐analysis

Campbell, B. E., Lodge, C. J., Lowe, A. J., Burgess, J. A., Matheson, M. C., & Dharmage, S. C. (2015) · Clinical & Experimental Allergy · doi:10.1111/cea.12429 · Cited by 60 · see citing works

Indoor allergens, asthma, and asthma-related symptoms among adolescents in Wuhan, China

Salo, P. M., Xia, J., Johnson, C. A., Li, Y., Avol, E. L., Gong, J., & London, S. J. (2004) · Annals of Epidemiology · doi:10.1016/j.annepidem.2003.09.015 · Cited by 60 · see citing works

Lipopolysaccharide inhalation exacerbates allergic airway inflammation by activating mast cells and promoting Th2 responses

Murakami, D., Yamada, H., Yajima, T., Masuda, A., Komune, S., & Yoshikai, Y. (2006) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2006.02633.x · Cited by 59 · see citing works

The EuroPrevall‐INCO surveys on the prevalence of food allergies in children from China, India and Russia: the study methodology

Wong, G., Mahesh, P. A., Ogorodova, L. M., Leung, T. F., Fedorova, O. S., Holla, A., Fernández‐Rivas, M., Mills, E. N. C., Kummeling, I., van Ree, R., et al. (2009) · Allergy · doi:10.1111/j.1398-9995.2009.02214.x · Cited by 58 · see citing works

Dissociation between the prevalence of atopy and allergic disease in rural China among children and adults

Kim, J. S., Ouyang, F., Pongracic, J. A., Fang, Y., Wang, B., Liu, X., Xing, H., Caruso, D., Liu, X., Zhang, S., et al. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.08.009 · Cited by 57 · see citing works

The protective effect of rural living against atopy in Mongolia

Viinanen, A., Munhbayarlah, S., Zevgee, T., Narantsetseg, L., Naidansuren, T., Koskenvuo, M., Helenius, H. Y. M., & Terho, E. O. (2007) · Allergy · doi:10.1111/j.1398-9995.2007.01279.x · Cited by 56 · see citing works

The Microbiome of the Built Environment and Human Behavior

Stamper, C. E., Hoisington, A. J., Gomez, O. M., Halweg‐Edwards, A. L., Smith, D. G., Bates, K. L., Kinney, K. A., Postolache, T. T., Brenner, L. A., Rook, G. A. W., et al. (2016) · International review of neurobiology · doi:10.1016/bs.irn.2016.07.006 · Cited by 56 · see citing works

Change in IFN-γ–producing capacity in early life and exposure to environmental microbes

Roponen, M., Hyvärinen, A., Hirvonen, M., Keski‐Nisula, L., & Pekkanen, J. (2005) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2005.08.039 · Cited by 53 · see citing works

Hygiene, atopy and wheeze–eczema–rhinitis symptoms in schoolchildren from urban and rural Ecuador

Cooper, P. J., Vaca, M. G., Rodríguez, A., Chico, M. E., dos Santos, D. N., Rodrigues, L. C., & Barreto, M. L. (2013) · Thorax · doi:10.1136/thoraxjnl-2013-203818 · Cited by 52 · see citing works

The effects of growing up on a farm on adult lung function and allergic phenotypes: an international population-based study

Campbell, B., Rahérison, C., Lodge, C., Lowe, A. J., Gíslason, Þ., Heinrich, J., Sunyer, J., Real, F. G., Norbäck, D., Matheson, M. C., et al. (2016) · Thorax · doi:10.1136/thoraxjnl-2015-208154 · Cited by 52 · see citing works

A review of bio-aerosol exposures and associated health effects in veterinary practice.

Samadi, S., Wouters, I. M., & Heederik, D. J. J. (2013) · PubMed · Cited by 51 · see citing works

ENVIRONMENTAL FACTORS AND GENE–ENVIRONMENT INTERACTIONS IN THE AETIOLOGY OF ASTHMA

Marks, G. B. (2006) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2006.04360.x · Cited by 51 · see citing works

Effects of Migration on Allergic Diseases

Tham, E. H., Loo, E. X. L., Zhu, Y., & Shek, L. P. (2018) · International Archives of Allergy and Immunology · doi:10.1159/000494129 · Cited by 50 · see citing works

Immune Evasion, Immunopathology and the Regulation of the Immune System

Sorci, G., Cornet, S., & Faivre, B. (2013) · Pathogens · doi:10.3390/pathogens2010071 · Cited by 49 · see citing works

Halting the March: Primary Prevention of Atopic Dermatitis and Food Allergies

Bawany, F., Beck, L. A., & Järvinen, K. M. (2020) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2019.12.005 · Cited by 48 · see citing works

Environmental influences on childhood allergies and asthma — The Farm effect

Frei, R., Heye, K., & Roduit, C. (2022) · Pediatric Allergy and Immunology · doi:10.1111/pai.13807 · Cited by 45 · see citing works

Agricultural lung disease

Spurzem, J. R., Romberger, D. J., & Essen, S. G. V. (2002) · Clinics in Chest Medicine · doi:10.1016/s0272-5231(02)00024-2 · Cited by 46 · see citing works

Childhood asthma and continuous exposure to cats since the first year of life with cats allowed in the child's bedroom

Oberle, D., von Mutius, E., & von Kries, R. (2003) · Allergy · doi:10.1034/j.1398-9995.2003.00285.x · Cited by 44 · see citing works

Gene-Environment Interaction in Childhood Asthma

Rigoli, L. C., Briuglia, S., Caimmi, S. M. E., Ferraù, V., Gallizzi, R., Leonardi, S., Rosa, M. L., & Salpietro, C. D. (2011) · International Journal of Immunopathology and Pharmacology · doi:10.1177/03946320110240s409 · Cited by 44 · see citing works

The role of the farm environment and animal contact for the development of asthma and allergies

Braun‐Fahrländer, C. (2001) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2001.01269.x · Cited by 44 · see citing works

Cord Blood Derived CD4+CD25high T Cells Become Functional Regulatory T Cells upon Antigen Encounter

Mayer, E., Bannert, C., Gruber, S., Klunker, S., Spittler, A., Akdiş, C. A., Szépfalusi, Z., & Eiwegger, T. (2012) · PLoS ONE · doi:10.1371/journal.pone.0029355 · Cited by 41 · see citing works

Effect of farming environment on sensitisation to allergens continues after childhood

Koskela, H. O., Happonen, K. K., Remes, S., & Pekkanen, J. (2005) · Occupational and Environmental Medicine · doi:10.1136/oem.2004.014852 · Cited by 40 · see citing works

Regional variation in infant hypoallergenic formula prescriptions in Australia

Mullins, R. J., Clark, S., & Camargo, C. A. (2009) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2009.00962.x · Cited by 39 · see citing works

Increased sensitization in urban vs. rural environment – Rural protection or an urban living effect?

Priftis, K. Ν., Anthracopoulos, M. Β., Nickolaou, A., Mantziou, V., Paliatsos, A. G., Tzavelas, G., Nicolaidou, P., & Mantzouranis, E. C. (2007) · Pediatric Allergy and Immunology · doi:10.1111/j.1399-3038.2006.00514.x · Cited by 39 · see citing works

Hope for the Hygiene Hypothesis: When the Dirt Hits the Fan

Borchers, A. T., Keen, C. L., & Gershwin, M. E. (2005) · Journal of Asthma · doi:10.1081/jas-200051302 · Cited by 39 · see citing works

Contact with livestock – a protective effect against allergies and asthma?

Dimich‐Ward, H., Chow, Y., Chung, J., & Trask, C. (2006) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2006.02556.x · Cited by 38 · see citing works

The effect of atopy, childhood crowding, and other immune-related factors on non-Hodgkin lymphoma risk

Cozen, W., Cerhan, J. R., Martı́nez-Maza, O., Ward, M. H., Linet, M. S., Colt, J. S., Davis, S., Severson, R. K., Hartge, P. A., & Bernstein, L. (2007) · Cancer Causes & Control · doi:10.1007/s10552-007-9025-5 · Cited by 38 · see citing works

Increased Prevalence of Self-Reported Asthma Among Korean Adults: An Analysis of KNHANES I and IV Data

Kim, S. Y., Jung, J. Y., Park, M. S., Kang, Y. A., Kim, E. Y., Kim, S. I., Chang, J., & Kim, Y. S. (2013) · Lung · doi:10.1007/s00408-013-9453-9 · Cited by 36 · see citing works

The effects of farming and birth order on asthma and allergies

Zekveld, C., Bibakis, I., Bibaki‐Liakou, V., Pedioti, A., Dimitroulis, J., Harris, J., Taylor, A. J. N., & Cullinan, P. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00021305 · Cited by 36 · see citing works

Associations of Doctor-Diagnosed Asthma with Immigration Status, Age at Immigration, and Length of Residence in the United States in a Sample of Mexican American School Children in Chicago

Eldeirawi, K. M., McConnell, R., Furner, S. E., Freels, S. A., Stayner, L. T., Hernández, E., Amoruso, L., Torres, S., & Persky, V. (2009) · Journal of Asthma · doi:10.3109/02770900903114572 · Cited by 35 · see citing works

Asthma and allergies: is the farming environment (still) protective in P oland? The GABRIEL Advanced Studies

MacNeill, S., Sozańska, B., Danielewicz, H., Dębińska, A., Kosmeda, A., Boznański, A., Illi, S., Depner, M., Strunz‐Lehner, C., Waser, M., et al. (2013) · Allergy · doi:10.1111/all.12141 · Cited by 34 · see citing works

Socio‐economic status, geographic remoteness and childhood food allergy and anaphylaxis in Australia

Mullins, R. J., Clark, S., & Camargo, C. A. (2010) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2010.03573.x · Cited by 34 · see citing works

Correlation between pollen counts and symptoms in two different areas of the Iberian Peninsula: Cordoba (Spain) and Evora (Portugal).

Mesa, J. A. S., Brandao, R. M., Lopes, L., & Galán, C. (2005) · PubMed · Cited by 33 · see citing works

Another explanation for the low allergy rate in the rural Alpine foothills

Wjst, M. (2005) · Clinical and Molecular Allergy · doi:10.1186/1476-7961-3-7 · Cited by 31 · see citing works

Comparison of local risk factors for children's atopic symptoms in Hanoi, Vietnam

Chai, S. K., Nga, N. N., Checkoway, H., Takaro, T. K., Redding, G. J., Keifer, M., Trung, L. V., & Barnhart, S. (2004) · Allergy · doi:10.1111/j.1398-9995.2004.00463.x · Cited by 30 · see citing works

Characterisation of asthma among adults with and without childhood farm contact

Schulze, A., Strien, R. T. V., Praml, G., Nowak, D., & Radon, K. (2007) · European Respiratory Journal · doi:10.1183/09031936.00127906 · Cited by 29 · see citing works

The role of parasitic infections in atopic diseases in rural schoolchildren

Karadag, B. T., Ege, M. J., Bradley, J. E., Braun‐Fahrländer, C., Riedler, J., Nowak, D., & von Mutius, E. (2006) · Allergy · doi:10.1111/j.1398-9995.2006.01107.x · Cited by 29 · see citing works

Ecological associations between asthma prevalence and potential exposure to farming

Elliott, L., Yeatts, K., & LOOMIS, D. P. (2004) · European Respiratory Journal · doi:10.1183/09031936.04.00006404 · Cited by 30 · see citing works

Airborne Bacteria and Endotoxin

Thorne, P. S., & Duchaine, C. (2007) · Wiley eBooks · doi:10.1128/9781555815882.ch78 · Cited by 28 · see citing works

Reduced Risk of Atopic Sensitization among Farmers: The Humboldt Study

Chen, Y., Rennie, D., Cormier, Y. F., McDuffie, H. H., Pahwa, P., & Dosman, J. A. (2007) · International Archives of Allergy and Immunology · doi:10.1159/000106460 · Cited by 27 · see citing works

The role of respiratory viruses in the origin and exacerbations of asthma

Papadopoulos, N. G., Psarras, S., Manoussakis, E., & Saxoni‐Papageorgiou, P. (2003) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/00130832-200302000-00007 · Cited by 27 · see citing works

TLRs, NLRs and RLRs: Innate sensors and their impact on allergic diseases – A current view

Heine, H. (2011) · Immunology Letters · doi:10.1016/j.imlet.2011.04.010 · Cited by 26 · see citing works

Farming and asthma

Schenker, M. B. (2005) · Occupational and Environmental Medicine · doi:10.1136/oem.2004.019109 · Cited by 26 · see citing works

Oral administration of bovine colostrum stimulates intestinal intraepithelial lymphocytes to polarize Th1-type in mice

Yoshioka, Y., Kudo, S., Nishimura, H., Yajima, T., Kishihara, K., Saito, K., Suzuki, T., Suzuki, Y., Kuroiwa, S., & Yoshikai, Y. (2004) · International Immunopharmacology · doi:10.1016/j.intimp.2004.11.005 · Cited by 25 · see citing works

What should we tell allergic families about pets?

Marks, G. B. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.119383 · Cited by 25 · see citing works

Mechanism of asthmatic exacerbation by ambient air pollution particles

Ghio, A. J. (2008) · Expert Review of Respiratory Medicine · doi:10.1586/17476348.2.1.109 · Cited by 24 · see citing works

Prevalence and determinants of atopy and allergic diseases among school-age children in rural Saskatchewan, Canada

Chu, L. M., Rennie, D., Cockcroft, D. W., Pahwa, P., Dosman, J. A., Hagel, L. M., Karunanayake, C. P., Pickett, W., & Lawson, J. A. (2014) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2014.07.003 · Cited by 22 · see citing works

Primary prevention of asthma

Becker, A. B., & Chan-Yeung, M. M. W. (2002) · Current Opinion in Pulmonary Medicine · doi:10.1097/00063198-200201000-00004 · Cited by 21 · see citing works

Microbial Air Contamination in Farmhouses – Quantitative Aspects

Lis, D. O., Mainelis, G., & Górny, R. L. (2008) · CLEAN - Soil Air Water · doi:10.1002/clen.200800003 · Cited by 20 · see citing works

Epidemiology of bronchial asthma among preparatory school children in Assiut district

Abdallah, A. M., Sanusy, K. A., Said, W. S., Mahran, D. G., & Hussein, A. A. R. M. (2012) · The Egyptian Journal of Pediatric Allergy and Immunology · Cited by 20 · see citing works

Differences between preschoolers with asthma and allergies in urban and rural environments

Marfortt, D., Josviack, D., Lozano, A., Cuestas, E., Agüero, L., & Castro-Rodríguez, J. A. (2017) · Journal of Asthma · doi:10.1080/02770903.2017.1339800 · Cited by 20 · see citing works

Small nonspecialized farming as a protective factor against immediate‐type occupational respiratory allergy?

Walusiak‐Skorupa, J., Krawczyk-Adamus, P., Hanke, W., Wittczak, T., & Palczynski, C. M. (2004) · Allergy · doi:10.1111/j.1398-9995.2004.00560.x · Cited by 19 · see citing works

Reduced risk of hay fever and asthma among children of farmers

Ehrenstein, V., Mutius, V., Illi, Baumann, Böhm, & Kries, V. (2000) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2000.00801.x · Cited by 718 · see citing works

Prevalence and determinants of atopy and allergic diseases among school-age children in rural Saskatchewan, Canada

Chu, L. M., Rennie, D., Cockcroft, D. W., Pahwa, P., Dosman, J. A., Hagel, L. M., Karunanayake, C. P., Pickett, W., & Lawson, J. A. (2014) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2014.07.003 · Cited by 22 · see citing works

Influence Of Farm Childhood On Allergic Diseases And Atopy

Lee, S., Song, Y., Park, K., Kwon, J., Kim, B., Kim, H., Lee, C., Yu, J., & Hong, S. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2009.12.818

Prevalence of wheezing and atopic diseases in Austrian schoolchildren in conjunction with urban, rural or farm residence

on behalf of the GABRIEL Study Group, Horak, E., Morass, B., Ulmer, H., Genuneit, J., Braun‐Fahrländer, C., & von Mutius, E. (2014) · Wiener klinische Wochenschrift · doi:10.1007/s00508-014-0571-z · Cited by 22 · see citing works

Does Living on a Farm During Childhood Protect Against Asthma, Allergic Rhinitis, and Atopy in Adulthood?

Williams, L. W. (2002) · PEDIATRICS · doi:10.1542/peds.110.s2.432b