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Cited by 1,246

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Microsatellites: genomic distribution, putative functions and mutational mechanisms: a review

Open access
Li, You‐Chun, Korol, Abraham B., Fahima, Tzion, Beiles, Avigdor, Nevo, Eviatar·2002·Molecular Ecology
DOI 10.1046/j.1365-294x.2002.01643.x
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Abstract

Microsatellites, or tandem simple sequence repeats (SSR), are abundant across genomes and show high levels of polymorphism. SSR genetic and evolutionary mechanisms remain controversial. Here we attempt to summarize the available data related to SSR distribution in coding and noncoding regions of genomes and SSR functional importance. Numerous lines of evidence demonstrate that SSR genomic distribution is nonrandom. Random expansions or contractions appear to be selected against for at least part of SSR loci, presumably because of their effect on chromatin organization, regulation of gene activity, recombination, DNA replication, cell cycle, mismatch repair system, etc. This review also discusses the role of two putative mutational mechanisms, replication slippage and recombination, and their interaction in SSR variation.

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Metadata

Authors
Li, Y., Korol, A. B., Fahima, T., Beiles, A., & Nevo, E.
Venue
Molecular Ecology
Publisher
Wiley
Published
2002-12
Volume
11
Issue
12
Pages
2453-2465
ISSN
  • 0962-1083 (ISSN-L)
  • 1365-294X
DOI
10.1046/j.1365-294x.2002.01643.x
OpenAlex
W2134770471
Cited by
1,246
References
2
FWCI
13.01
Type
journal article
Language
en
Open access
bronze

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