The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
The contribution of melanin to microbial pathogenesis: Melanin and microbial pathogenesis
Open accessAbstract
Melanins are enigmatic pigments that are produced by a wide variety of microorganisms including several species of pathogenic bacteria, fungi and helminths. The study of melanin is difficult because these pigments defy complete biochemical and structural analysis. Nevertheless, the availability of new reagents in the form of monoclonal antibodies and melanin-binding peptides, combined with the application of various physical techniques, has provided insights into the process of melanization. Melanization is important in microbial pathogenesis because it has been associated with virulence in many microorganisms. Melanin appears to contribute to virulence by reducing the susceptibility of melanized microbes to host defence mechanisms. However, the interaction of melanized microbes and the host is complex and includes immune responses to melanin-related antigens. Production of melanin has also been linked to protection against environmental insults. Interference with melanization is a potential strategy for antimicrobial drug and pesticide development. The process of melanization poses fascinating problems in cell biology and provides a type of pathogenic strategy that is common to highly diverse pathogens.
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Citations
Cites
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Self-citationMelanin, melanin “ghosts,” and melanin composition in Cryptococcus neoformans
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Self-citationResistance of some common fungi to gamma irradiation
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The antibody response to fungal melanin in mice
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Self-citationProtein and gene structure of a blue laccase from Pleurotus ostreatus
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Cited by
Synthesis and assembly of fungal melanin
Eisenman, H. C., & Casadevall, A. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3777-2 · Cited by 711
Self-citationMedically important bacterial-fungal interactions
Peleg, A. Y., Hogan, D. A., & Mylonakis, E. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2313 · Cited by 619
Dadachova, E., Bryan, R. A., Huang, X., Moadel, T., Schweitzer, A. D., Aisen, P., Nosanchuk, J. D., & Casadevall, A. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000457 · Cited by 463
Self-citationSystematic Genetic Analysis of Virulence in the Human Fungal Pathogen Cryptococcus neoformans
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Autofluorescence of atmospheric bioaerosols – fluorescent biomolecules and potential interferences
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Metadata
- Authors
- Nosanchuk, J. D., & Casadevall, A.
- Venue
- Cellular Microbiology
- Publisher
- Hindawi Limited
- Published
- 2003-04
- Volume
- 5
- Issue
- 4
- Pages
- 203-223
- ISSN
- 1462-5814 (ISSN-L)
- OpenAlex
- W2109383062
- Cited by
- 650
- References
- 8
- FWCI
- 12.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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