The significance of crown–rump length measurement for predicting adverse pregnancy outcome of threatened abortion
Abstract
Objectives: To determine if in women with threatened miscarriage the measurement of fetal crown–rump length (CRL) is a useful predictor of spontaneous miscarriage and small for gestational age (SGA) infants. Methods: Fetal CRL was measured in 310 singleton pregnancies with live fetuses, presenting with threatened miscarriage before 13 weeks of gestation. The relationship between fetal CRL and pregnancy outcome was investigated. Results: In fetuses with CRL < 18 mm there was a significant positive association between the deficit in CRL for gestation and the incidence of subsequent spontaneous miscarriage. In those cases with CRL deficit more than 2 standard deriations (SDs) the incidence of miscarriage was 13.7%, whereas if the CRL was between the mean and −2 SDs the incidence of miscarriage was 8.3%. In fetuses with CRL ≥ 18 mm there was a significant positive association between the deficit in CRL for gestation and the incidence of SGA. In those cases with CRL deficit of more than 2 SD the incidence of SGA was 27.3%, whereas if the CRL was between the mean and −2 SDs the incidence of SGA was 18.9%. Conclusions: The findings of this study suggest that the measurement of fetal CRL may be a useful predictor of spontaneous miscarriage and SGA in pregnancies with threatened miscarriage. Copyright © 2001 International Society of Ultrasound in Obstetrics and Gynecology
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Most existing studies investigate the individual components of the first-trimester ultrasound for predicting miscarriage.
“Most existing studies investigate the individual components of the first-trimester ultrasound for predicting miscarriage [9, 25, 26].”
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- Authors
- Reljič, M.
- Corresponding author
- Reljič, M.
- ORCID
- Reljič, M.
- Venue
- Ultrasound in Obstetrics & Gynecology
- Publisher
- Wiley
- Published
- 2001-06
- Volume
- 17
- Issue
- 6
- Pages
- 510-512
- ISSN
- 0960-7692 (ISSN-L)
- 1469-0705
- OpenAlex
- W2020536140
- Cited by
- 71
- References
- 19
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 4 · 2019: 1 · 2017: 8 · 2016: 2 · 2015: 4 · 2014: 3 · 2013: 1 · 2012: 3
- FWCI
- 1.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Ultrasound in Obstetrics and Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Screening and Diagnostics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Keywords
- crown-rump length, threatened abortion, miscarriage, small for gestational age, adverse pregnancy outcomes, fetal growth restriction, early pregnancy, second-trimester ultrasound
- MeSH terms
- Abortion, Spontaneous, Adult, Anthropometry, Female, Embryonic and Fetal Development, Humans, Infant, Newborn, Infant, Small for Gestational Age, Parity, Predictive Value of Tests, Pregnancy, Prospective Studies, Sensitivity and Specificity, Prevalence, Ultrasonography, Prenatal, Crown-Rump Length, Risk Assessment
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