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Multiple sulphur isotopic interpretations of biosynthetic pathways: implications for biological signatures in the sulphur isotope record

Farquhar, James, Johnston, David T., Wing, Boswell A., Habicht, Kirsten S., Canfield, Donald E., Airieau, Sabine, Thiemens, Mark H.·2003·Geobiology

DOI 10.1046/j.1472-4669.2003.00007.x

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Abstract

Isotopic fractionations produced by biosynthetic processes are the result of networks of individual biochemical reactions that operate at differing efficiencies and with distinct fractionation factors. These reaction networks determine the magnitude and direction of the net isotopic fractionation associated with a given process. Here we examine the ways that biological reaction networks control mass‐dependent isotopic fractionations of multiple sulphur isotopes. We describe how material‐flow through some networks can produce characteristic multiple‐sulphur‐isotope signatures that differ from those produced by their constituent steps and demonstrate that experimental results with Archaeaglobus fulgidus can be evaluated using multiple sulphur isotopes in the context of previously published models for dissimilatory sulphate reduction. Our evaluation of these data is consistent with the interpretation that the dependence of sulphur isotope fractionation on external sulphate concentration is rooted in differences between the forward and reverse ↔ adenosine‐5′‐phosphosulphate (APS) ↔ steps. The framework provided by our analysis has the potential to evaluate the biosynthetic pathways that produce the isotopic fractionations, to isolate the primary sources of isotopic fractionations (sulphate reduction or disproportionation reactions) and to establish criteria to identify the signature of specific sulphur metabolisms in the geological record. The results highlight the new types of information that can be obtained by including measurements of δ 33 S {δ 33 S = [(33 S/32 S)sample/(33 S/32 S)reference − 1]*1000} with measurements of δ 34 S.

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Brock Biology of Microorganisms
Madigan, M. T., Bender, K. S., Buckley, D. H., Sattley, W. M., & Stahl, D. A. (1996) · Cited by 5,759
The thermodynamic properties of isotopic substances
Urey, H. C. (1947) · Journal of the Chemical Society (Resumed) · doi:10.1039/jr9470000562 · Cited by 2,544
Atmospheric Influence of Earth's Earliest Sulfur Cycle
Farquhar, J., Bao, H., & Thiemens, M. (2000) · Science · doi:10.1126/science.289.5480.756 · Cited by 1,805
Self-citation
Infra-Red and Raman Spectra of Polyatomic Molecules
Thompson, H. W. (1946) · Nature · doi:10.1038/158289a0 · Cited by 1,272
A new model for Proterozoic ocean chemistry
Canfield, D. E. (1998) · Nature · doi:10.1038/24839 · Cited by 1,243
Self-citation
Kinetic and equilibrium mass-dependent isotope fractionation laws in nature and their geochemical and cosmochemical significance
Young, E., Galy, Α., & Nagahara, H. (2002) · Geochimica et Cosmochimica Acta · doi:10.1016/s0016-7037(01)00832-8 · Cited by 964
Late Proterozoic rise in atmospheric oxygen concentration inferred from phylogenetic and sulphur-isotope studies
Canfield, D. E., & Teske, A. (1996) · Nature · doi:10.1038/382127a0 · Cited by 869
Self-citation
Microbiological Fractionation of Sulphur Isotopes
Kaplan, I. R., & Rittenberg, S. C. (1964) · Journal of General Microbiology · doi:10.1099/00221287-34-2-195 · Cited by 866
Fractionation of Carbon and Hydrogen Isotopes in Biosynthetic Processes
Hayes, J. M. (2001) · Reviews in Mineralogy and Geochemistry · doi:10.2138/gsrmg.43.1.225 · Cited by 792
A Review of Hydrogen, Carbon, Nitrogen, Oxygen, Sulphur, and Chlorine Stable Isotope Fractionation Among Gaseous Molecules
Richet, P., Bottinga, Y., & Javoy, M. (1977) · Annual Review of Earth and Planetary Sciences · doi:10.1146/annurev.ea.05.050177.000433 · Cited by 773

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Herzberg G, 1962, Infrared and Raman Spectra of Polyatomic Molecules.
Madigan MT, 2003, Brock Biology of Micro organisms
Mook WG, 2000, Environmental Isotopes in the Hydrological Cycle Principles and Applications, V, I: Introduction–Theory, Methods, Review
Nakamoto K, 1997, Infrared and Raman Spectra of Inorganic and Coordination Compounds part A: Theory and Applications in Inorganic Chemistry

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Authors: Farquhar, J., Johnston, D. T., Wing, B. A., Habicht, K. S., Canfield, D. E., Airieau, S., & Thiemens, M. H.
Affiliations: Earth System Science Interdisciplinary Center (US)
University of Southern Denmark (DK)
University of California San Diego (US)
Corresponding author: Farquhar, James
ORCID: Farquhar, James
Johnston, David T.
Wing, Boswell A.
Canfield, Donald E.
Thiemens, Mark H.
Venue: Geobiology
Publisher: Wiley
Published: 2003-07
Volume: 1
Issue: 1
Pages: 27-36
ISSN: 1472-4669 (ISSN-L)
1472-4677
DOI: 10.1046/j.1472-4669.2003.00007.x
OpenAlex: W2108421893
Cited by: 256
References: 39
Citations by year: 2026: 9 · 2025: 6 · 2024: 6 · 2023: 9 · 2022: 9 · 2021: 19 · 2020: 14 · 2019: 14 · 2018: 11 · 2017: 18 · 2016: 12 · 2015: 16 · 2014: 15 · 2013: 12 · 2012: 9
FWCI: 5.81
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Geobiology (publishedVersion)
University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
Funders: NASA Astrobiology Institute
Topics: Physical Sciences › Earth and Planetary Sciences › Paleontology › Paleontology and Stratigraphy of Fossils
Physical Sciences › Earth and Planetary Sciences › Geochemistry and Petrology › Geological and Geochemical Analysis
Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
Keywords: sulfur isotope fractionation, biosynthetic pathway, mass-dependent fractionation, dissimilatory sulfate reduction, sulfate reduction

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Multiple sulphur isotopic interpretations of biosynthetic pathways: implications for biological signatures in the sulphur isotope record

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