The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
The Role of Carotenoids in Human Health
Abstract
Dietary carotenoids are thought to provide health benefits in decreasing the risk of disease, particularly certain cancers and eye disease. The carotenoids that have been most studied in this regard are β‐carotene, lycopene, lutein, and zeaxanthin. In part, the beneficial effects of carotenoids are thought to be due to their role as antioxidants. β‐Carotene may have added benefits due its ability to be converted to vitamin A. Furthermore, lutein and zeaxanthin may be protective in eye disease because they absorb damaging blue light that enters the eye. Food sources of these compounds include a variety of fruits and vegetables, although the primary sources of lycopene are tomato and tomato products. Additionally, egg yolk is a highly bioavailable source of lutein and zeaxanthin. These carotenoids are available in supplement form. However, intervention trials with large doses of β‐carotene found an adverse effect on the incidence of lung cancer in smokers and workers exposed to asbestos. Until the efficacy and safety of taking supplements containing these nutrients can be determined, current dietary recommendations of diets high in fruits and vegetables are advised.
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Cites
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Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease
Omenn, G. S., Goodman, G. E., Thornquist, M. D., Balmes, J., Cullen, M. R., Glass, A., Keogh, J. P., Meyskens, F. L., Valanis, B., Williams, J. H., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605023341802 · Cited by 3,638
Validation of a self-administered diet history questionnaire using multiple diet records
Block, G., Woods, M., Potosky, A., & Clifford, C. (1990) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(90)90099-b · Cited by 1,197
Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration
Seddon, J. M. (1994) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1994.03520180037032 · Cited by 993
A case-control study of gastric cancer and diet in Italy
Buiatti, E., Palli, D., Decarli, A., Amadori, D., Avellini, C., Bianchi, S., Biserni, R., Cipriani, F., Cocco, P., Giacosa, A., et al. (1989) · International Journal of Cancer · doi:10.1002/ijc.2910440409 · Cited by 547
Antioxidant status and neovascular age-related macular degeneration
(1993) · Archives of Ophthalmology · doi:10.1001/archopht.1993.01090010108035 · Cited by 304
Concentrations of selected carotenoids and Vitamin A in human liver, kidney and lung tissue
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Cited by
Bouayed, J., & Bohn, T. (2010) · Oxidative Medicine and Cellular Longevity · doi:10.4161/oxim.3.4.12858 · Cited by 1,095
Factors Influencing the Chemical Stability of Carotenoids in Foods
Boon, C. S., McClements, D. J., Weiss, J., & Decker, E. A. (2010) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390802565889 · Cited by 828
Antioxidants in wild mushrooms
Ferreira, I., Barros, L., & Abreu, R. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709787909587 · Cited by 670
The Antioxidants and Pro-Antioxidants Network: An Overview
Vertuani, S., Angusti, A., & Manfredini, S. (2004) · Current Pharmaceutical Design · doi:10.2174/1381612043384655 · Cited by 438
Carotenoids: potential allies of cardiovascular health?
Maria, A. G., Graziano, R., & Nicolantonio, D. (2015) · Food & Nutrition Research · doi:10.3402/fnr.v59.26762 · Cited by 323
Metadata
- Authors
- Johnson, E. J.
- Venue
- Nutrition in Clinical Care
- Publisher
- Wiley
- Published
- 2002-04
- Volume
- 5
- Issue
- 2
- Pages
- 56-65
- ISSN
- 1096-6781 (ISSN-L)
- 1523-5408
- OpenAlex
- W2134882067
- Cited by
- 569
- References
- 8
- FWCI
- 5.24
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
