The DOI matches its Crossref record; 42 of the 43 references it cites were found in a registry or an index.
Heart Rate and Heart Rate Variability Changes in the Intracarotid Sodium Amobarbital Test
Open accessAbstract
PURPOSE: Changes in heart rate and heart rate variability have been found in prior studies performed during the intracarotid sodium amobarbital (ISA) test. However, these results are not entirely consistent with current models of differential cerebral involvement in the modulation of the heart. This study was designed to re-investigate this topic with a larger N than has heretofore been used. METHODS: The electrocardiogram was recorded during left and right ISAs in 73 subjects. Raw heart rate and heart rate variability were calculated. RESULTS: Raw heart rate increased during inactivation of either hemisphere, but more so for the right hemisphere. Heart rate variability changes consistent with decreasing parasympathetic tone also were found to occur during either ISA, but to a significant degree, only during right ISA. CONCLUSIONS: The right hemisphere appears to have a greater role in cerebral regulation of cardiac function, perhaps by virtue of the modification of parasympathetic effects.
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“The stress response is mediated by subcortical areas in the brain, i.e. the so called limbic structures, including the amygdala, and it is normally under continuous ('tonic') inhibition by the prefrontal cortex (PFC; Ahern et al., 2001), more specifically by the ventromedial PFC (vmPFC; Motzkin et al., 2015).”
From Exposed to events that never happen: generalized unsafety, the default stress response, and prolonged autonomic activity (2017) · cites this paper as Ahern et al., 2001
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“the stress response is a default response”
From Exposed to events that never happen: generalized unsafety, the default stress response, and prolonged autonomic activity (2017) · cites this paper as Ahern et al., 2001
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Heart Rate Variability: Standards of Measurement, Physiological Interpretation, and Clinical Use
Electrophysiology, T. F. O. T. E. S. O. C. T. N. A. (1996) · Circulation · doi:10.1161/01.cir.93.5.1043 · Cited by 17,159
Heart rate variability: Standards of measurement, physiological interpretation, and clinical use
Malik, M., Bigger, J. T., Camm, A. J., Kleiger, R. E., Malliani, A., Moss, A. J., & Schwartz, P. J. (1996) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a014868 · Cited by 15,289
A model of neurovisceral integration in emotion regulation and dysregulation
Thayer, J. F., & Lane, R. D. (2000) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00338-4 · Cited by 3,092
Mayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416
Intracarotid Injection of Sodium Amytal for the Lateralization of Cerebral Speech Dominance
Wada, J., & Rasmussen, T. (1960) · Journal of neurosurgery · doi:10.3171/jns.1960.17.2.0266 · Cited by 1,576
The Central Autonomic Network: Functional Organization, Dysfunction, and Perspective
BENARROCH, E. E. (1993) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)62272-1 · Cited by 1,534
Katirji, M. B. (1993) · Neurology · doi:10.1212/wnl.43.11.2429 · Cited by 590
Gender- and age-related differences in heart rate dynamics: Are women more complex than men?
Ryan, S. M., Goldberger, A. L., Pincus, S. M., Mietus, J. E., & Lipsitz, L. A. (1994) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)90177-5 · Cited by 454
Hypoarousal in patients with the neglect syndrome and emotional indifference
Heilman, K. M., Schwartz, H. D., & Watson, R. T. (1978) · Neurology · doi:10.1212/wnl.28.3.229 · Cited by 411
Cortical Modulation of theCardiovascular System
Verberne, A. J. M., & Owens, N. C. (1998) · Progress in Neurobiology · doi:10.1016/s0301-0082(97)00056-7 · Cited by 351
Research works printed but not linked: 4
- Rosen AD, 1982, Hemispheric asymmetry in the control of heart rate., Soc Neurosci Abstr, 8, 917
- Mehta C, 1995, StatXact 3 user manual
- Preston E, 1995, Physiological correlates of vagus nerve innervation in lower vertebrates., Am J Physiol, 268, 1249
- 10.1037//0033-2909.120.2.163 · DOI
Cited by
Sorted by citations
Thayer, J. F., & Lane, R. D. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.08.004 · Cited by 2,040
Thayer, J. F., Hansen, A. L., Saus-Rose, E., & Johnsen, B. H. (2009) · Annals of Behavioral Medicine · doi:10.1007/s12160-009-9101-z · Cited by 1,872
The role of vagal function in the risk for cardiovascular disease and mortality
Thayer, J. F., & Lane, R. D. (2007) · Biological Psychology · doi:10.1016/j.biopsycho.2005.11.013 · Cited by 1,033
Self-citationHeart rate variability as a transdiagnostic biomarker of psychopathology
Beauchaine, T. P., & Thayer, J. F. (2015) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2015.08.004 · Cited by 870
Neural correlates of heart rate variability during emotion
Lane, R. D., Kateri Mcrae, A., Reiman, E. M., Chen, K., Ahern, G. L., & Thayer, J. F. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.07.056 · Cited by 687
Metadata
- Authors
- Ahern, G. L., Sollers, J. J., Lane, R. D., Labiner, D. M., Herring, A. M., Weinand, M. E., Hutzler, R., & Thayer, J. F.
- Affiliations
- University of Arizona (US)
- National Institute on Aging (US)
- Corresponding author
- Ahern, Geoffrey L.
- Venue
- Epilepsia
- Publisher
- Wiley
- Published
- 2001-07-07
- Volume
- 42
- Issue
- 7
- Pages
- 912-921
- ISSN
- 0013-9580 (ISSN-L)
- 1528-1167
- OpenAlex
- W1988655270
- Cited by
- 195
- References
- 43
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 6 · 2023: 9 · 2022: 7 · 2021: 10 · 2020: 8 · 2019: 3 · 2018: 7 · 2017: 4 · 2016: 11 · 2015: 12 · 2014: 9 · 2013: 12 · 2012: 17
- FWCI
- 4.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Epilepsia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
- Keywords
- heart rate, heart rate variability, hemispheric lateralization, parasympathetic activity, electrocardiogram
- MeSH terms
- Adolescent, Adult, Aged, Amobarbital, Analysis of Variance, Autonomic Nervous System, Brain, Carotid Artery, Internal, Electrocardiography, Epilepsy, Female, Heart, Heart Rate, Humans, Infusions, Intra-Arterial, Functional Laterality, Male, Middle Aged, Vagus Nerve
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