Effect of dietary ?-carotene on the accumulation of ?-carotene and vitamin A in plasma and tissues of gilts
Open accessAbstract
The absorption of beta-carotene in pigs is limited. Nevertheless beta-carotene might positively affect reproduction. In this study the absorption and tissue distribution of beta-carotene as well as its function as precursor of vitamin A was investigated in gilts that were fed according to one of three dietary treatments: VA (4000 IU vitamin A), VA + VA (4000 IU + 8300 IU) and VA + BC (4000 IU + 100 mg beta-carotene per kg diet) for 14 weeks. Only in the VA + BC group was beta-carotene detected in plasma (1-8 ng x mL(-1)), liver, adrenals and corpora lutea, indicating that pigs absorb intact beta-carotene at low rates. Liver levels of vitamin A were higher (P < 0.01) at comparable levels in the VA + VA and VA + BC group than in the VA group, indicating a conversion rate of beta-carotene to vitamin A of 40 to 1 on the basis of weight for beta-carotene at this level (100 mg x kg(-1)) in the diet. Higher levels of vitamin A in the uterus of the VA + BC group (P < 0.01) as well as the accumulation of beta-carotene in adrenals and corpora lutea might reflect some influence of beta-carotene on local vitamin A metabolism which might be of importance for reproductive performance in gilts.
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The highest vitamin A content in the liver is usually reported in pigs.
“The values found in individual studies vary considerably, but the highest vitamin A content in the liver is usually reported in pigs [56,57,58,59,60].”
From Vitamin A Update: Forms, Sources, Kinetics, Detection, Function, Deficiency, Therapeutic Use and Toxicity (2021) · cites this paper as [60]
Section 3.2 reports vitamin A concentrations in gilt livers and says they were higher than in the other tissues examined. It does not compare liver concentrations across species, so it cannot establish that pigs usually have the highest liver vitamin A content. (LLM, conf=0.79)
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Carazo, A., Macáková, K., Matoušová, K., Krčmová, L. K., Protti, M., & Mladěnka, P. (2021) · Nutrients · doi:10.3390/nu13051703 · Cited by 418 · see citing works
- Authors
- Schweigert, F. J., Buchholz, I., Schuhmacher, A., & Gropp, J.
- Affiliations
- Leipzig University (DE)
- Venue
- Reproduction Nutrition Development
- Publisher
- EDP Sciences
- Published
- 2001-01
- Volume
- 41
- Issue
- 1
- Pages
- 47-55
- ISSN
- 0003-388X (ISSN-L)
- 0926-5287
- 1297-9708
- OpenAlex
- W2162866837
- Cited by
- 25
- References
- 29
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 5 · 2022: 1 · 2021: 2 · 2020: 1 · 2017: 2 · 2016: 1 · 2015: 1 · 2013: 1 · 2012: 1
- FWCI
- 0.60
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- annales de biologie animale biochimie biophysique (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinoids in leukemia and cellular processes
- Keywords
- beta-carotene, vitamin A, gilts, swine reproduction, plasma carotenoids, liver, uterus, corpus luteum, adrenal gland, dietary supplementation
- MeSH terms
- Absorption, Adrenal Glands, Animals, Animal Feed, Corpus Luteum, Female, Kidney, Liver, Lung, Reproduction, Swine, Tissue Distribution, Uterus, Vitamin A, beta Carotene
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