Urinary Sediment Findings in Acute Interstitial Nephritis
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Nephrotic-range proteinuria is rare in AIN, and when found in the setting of AIN it should raise suspicion for NSAID-induced nephrotoxicity or underlying glomerular diseases.
“However, nephrotic-range proteinuria is rare [4, 5, 10, 28, 85, 86], and when found in the setting of AIN, it should raise suspicion for NSAID-induced nephrotoxicity or underlying glomerular diseases [5, 10, 87, 88].”
From The diagnosis of acute interstitial nephritis caused by infection versus antibiotic-induced interstitial nephritis: a narrative review (2024) · cites this paper as [85]
Hematuria is a nonspecific and insensitive laboratory test in AIN, with a mean of 50% and a range of 20%-80%.
“Hematuria is also a nonspecific and insensitive laboratory test, despite several studies indicating a mean of 50% (with a range of 20%–80%) in cases of AIN [10, 85].”
From The diagnosis of acute interstitial nephritis caused by infection versus antibiotic-induced interstitial nephritis: a narrative review (2024) · cites this paper as [85]
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“However, nephrotic-range proteinuria is rare [4 , 5 , 10 , 28 , 85 , 86 ], and when found in the setting of AIN, it should raise suspicion for NSAID-induced nephrotoxicity or underlying glomerular diseases [5 , 10 , 87 , 88 ].”
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- Authors
- Fogazzi, G. B., Ferrari, B., Garigali, G., Simonini, P., & Consonni, D.
- Affiliations
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Corresponding author
- Fogazzi, Giovanni B.
- Venue
- American Journal of Kidney Diseases
- Publisher
- Elsevier BV
- Published
- 2012-08
- Volume
- 60
- Issue
- 2
- Pages
- 330-332
- ISSN
- 0272-6386 (ISSN-L)
- OpenAlex
- W2017052406
- Cited by
- 71
- References
- 11
- Citations by year
- 2026: 3 · 2025: 7 · 2024: 7 · 2023: 8 · 2022: 10 · 2021: 8 · 2020: 3 · 2019: 7 · 2018: 1 · 2017: 2 · 2016: 4 · 2015: 6 · 2014: 2 · 2013: 2 · 2012: 1
- FWCI
- 2.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Kidney Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Nephrology › Acute Kidney Injury Research
- Health Sciences › Medicine › Nephrology › Renal Diseases and Glomerulopathies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Nephrotoxicity and Medicinal Plants
- Keywords
- acute interstitial nephritis, urine sediment, renal biopsy, acute kidney injury, urinary findings
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Nephritis, Interstitial
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